Search results for "LSA"
showing 10 items of 832 documents
Sääksmäen ja Hollolan kihlakuntien rajakiista
1733
The NMDA receptor complex: a promising target for novel antiepileptic strategies.
2001
Antiepileptic drugs (AEDs) cover a broad spectrum of pathological conditions ranging from seizures following congenital or acquired brain disorders to behavioural and psychiatric disorders and recently neuropathic pain. The need for novel antiepileptics raises from the expanding field of indications as well as from the fact, that special seizure types are refractory to common AEDs. In addition, many of the conventional antiepileptic drugs exhibit an unfavourable side-effect profile. Since there is growing evidence, that NMDA receptor activation might play a crucial role in epilepsy, NMDA receptor antagonists have become compounds of interest in preventing and treating seizures. This review …
Action of anticonvulsants on hippocampal slices in Mg-free medium
1989
The effects of six prototype anticonvulsant drugs were investigated on epileptiform field potential discharges evoked in hippocampal slices of rats by removing magnesium ions from the perfusion fluid in order to reveal a possible interaction with N-methyl-D-aspartate (NMDA) receptor activation. All drugs reduced the multiple discharges with the following order of potency: midazolam greater than carbamazepine = phenytoin = phenobarbital greater than ethosuximide = valproate. They had a stronger depressant effect on the later population spikes but none of them abolished the epileptiform discharge. These effects can be explained by known mechanisms of action of the anticonvulsants tested and l…
BPS Dionu BIoni, Neekstremālie atrisinājumi AdS_5 × S^5 telpā un AdS/CFT duāli objekti
2019
Dotajā darbā tiek meklēti neekstremālie atrisinājumi, kuri atbilst Dionu BIoniem vai citiem solitonu tipa atrisinājumiem. Kā zināms Dž. Švarca \cite{Schwarz:2014zsa}, H. Maldasena \cite{Maldacena:1998im} un R. Maijersa \cite{Myers:1999ps} darbos tiek analizēti dažādi ekstremālie atrisinājumi, dotajā darbā sākumā tiek analizēta D3 zondes brānas ekstremālā konstrukcija $ AdS_{5} \times S^{5} $ telpā. Nākamajā posma šī ģeometrija tiek deformēta ieviešot metrikā melnos faktorus, kas arī attīsta notikuma horizonta jēdzienu (melnā brāna) un noved pie problēmas galīgo temperatūras atrisinājumu eksistenci un to interpretācijas. Ekstremālajā gadījumā ($ T = 0 $) tiek dots neatkarīgs jauns izvedums, …
Swings between rotation and accretion power in a binary millisecond pulsar
2013
It is thought that neutron stars in low-mass binary systems can accrete matter and angular momentum from the companion star and be spun-up to millisecond rotational periods1, 2, 3. During the accretion stage, the system is called a low-mass X-ray binary, and bright X-ray emission is observed. When the rate of mass transfer decreases in the later evolutionary stages, these binaries host a radio millisecond pulsar4, 5 whose emission is powered by the neutron star’s rotating magnetic field6. This evolutionary model is supported by the detection of millisecond X-ray pulsations from several accreting neutron stars7, 8 and also by the evidence for a past accretion disc in a rotation-powered milli…
Unilateral multicystic dysplastic kidney in infants exposed to antiepileptic drugs during pregnancy
2007
Prenatal exposure to antiepileptic drugs (AEDs) increases the risk of major congenital malformations (MCM) in the fetus. AED-related abnormalities include heart and neural tube defects, cleft palate, and urogenital abnormalities. Among the various congenital anomalies of the kidney and urinary tract (CAKUT), multicystic dysplastic kidney (MCDK) disease is one of the most severe expressions. Although prenatal ultrasound (US) examination has increased the prenatal diagnosis of MCDK, the pathogenesis is still unclear. We report on four cases of MCDK in infants of epileptic women treated with AEDs during pregnancy. From October 2003 to June 2006, we observed four infants with unilateral MCDK bo…
L'Agrément governativo e il controllo giurisdizionale sugli atti di provvista nei Dipartimenti dell'Alsazia-Mosella.
2015
Il nodo problematico su cui il presente saggio si sofferma concerne l'impugnabilità innanzi ai giudici amministrativi francesi del provvedimento vescovile di nomina di un parroco, emanato a seguito dell’‘agrément’ della competente autorità civile, da parte di chi ne abbia uno specifico interesse. The problematic node on which this essay focuses concerns the admissibility of the appointment of a parish priest before the French administrative judges of the bishop's office issued by the competent civil authority on behalf of those who have a specific interest.
El capitalismo, contra el planeta / 6
2007
Festival mediático
2007
Spatially resolved X-ray study of supernova remnants that host magnetars: Implication of their fossil field origin
2019
Magnetars are regarded as the most magnetized neutron stars in the Universe. Aiming to unveil what kinds of stars and supernovae can create magnetars, we have performed a state-of-the-art spatially resolved spectroscopic X-ray study of the supernova remnants (SNRs) Kes 73, RCW 103, and N49, which host magnetars 1E 1841-045, 1E 161348-5055, and SGR 0526-66, respectively. The three SNRs are O- and Ne-enhanced and are evolving in the interstellar medium with densities of >1--2 cm$^{-3}$. The metal composition and dense environment indicate that the progenitor stars are not very massive. The progenitor masses of the three magnetars are constrained to be < 20 Msun (11--15 Msun for Kes 73, …