Search results for "LTR"

showing 10 items of 6853 documents

Endometrial carcinoma and its precursors: Early detection and treatment

1990

Endometrial carcinoma is the most frequent genital neoplasia in women. Precursors of this condition include endometrial hyperplasia, particularly when cytologic atypia occurs. Among the frequent early clinical manifestations of endometrial carcinoma is abnormal uterine bleeding that must be differentiated from bleeding associated with benign conditions. Early detection of endometrial carcinoma and its precursors in women at risk is the best prophylactic measure in the final therapeutic outcome. In this review, the accuracy of methods of early diagnosis of endometrial carcinoma and its precursors is assessed, in order to provide early therapy and optimum prognosis. The epidemiology of endome…

medicine.medical_specialtyTime FactorsBiopsyHysteroscopyEarly TherapyEndometriumDilatation and CurettageRisk FactorsmedicineCarcinomaHumansUltrasonographyGynecologymedicine.diagnostic_testEpitheliomabusiness.industryObstetrics and GynecologyGeneral MedicineHyperplasiamedicine.diseaseEndometrial hyperplasiaEndoscopymedicine.anatomical_structureHysteroscopyEndometrial HyperplasiaUterine NeoplasmsFemalebusinessInternational Journal of Gynecology & Obstetrics
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Short- and long-term effects of vinblastine on the rat adrenal medulla

1979

The effects of a single high dose (10mg/kg) of vinblastine (vb) sulfate (“Velbe”, Lilly) on the ultrastructure, catecholamine (CA) content and activity of CA-synthesizing enzymes of the rat adrenal medulla were studied for up to 120h after intravenous injection of the drug.

medicine.medical_specialtyTime FactorsHistologyChemical PhenomenaVinblastinePathology and Forensic MedicineInternal medicineSingle high doseEnterochromaffin CellsmedicineAnimalsCells Culturedchemistry.chemical_classificationCell BiologyMolecular medicineRatsVinblastineChemistryEnzymemedicine.anatomical_structureEndocrinologychemistryAdrenal MedullaUltrastructureCatecholamineFemaleAdrenal medullamedicine.drugCell and Tissue Research
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Low-frequency ultrasound induces nonenzymatic thrombolysis in vitro.

2002

To evaluate whether ultrasound, applied over a distance of several centimeters and in the absence of thrombolytic agents, may have a thrombolytic effect on blood clots.Low-frequency (20 kHz) continuous wave ultrasound at different intensity levels (0.15-1.2 W/cm2) and exposure times (5, 10, and 20 minutes) was assessed for its potential to induce thrombolysis of fresh human blood clots. The ultrasound effect was also studied in combination with recombinant tissue-type plasminogen activator-mediated thrombolysis. Experiments were carried out in a flow model in degassed sodium phosphate buffer at 37 degrees C at a distance of 3 cm from the ultrasonic probe to the blood clots. Regardless of ul…

medicine.medical_specialtyTime FactorsRadiological and Ultrasound Technologybusiness.industrymedicine.medical_treatmentUltrasonic TherapyUltrasoundHemodynamicsThrombolysismedicine.diseaseThrombosisRecombinant ProteinsSurgeryThrombolytic drugTissue Plasminogen ActivatorFibrinolysismedicineThrombolytic AgentHumansRadiology Nuclear Medicine and imagingThrombolytic TherapybusinessNuclear medicinePlasminogen activatorJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
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Elimination of hexamethylene diisocyanate cross-linked polypeptides in patients with normal or impaired renal function

1978

Infusions of 3.5% isocyanate cross-linked polypeptide solution 500 ml were given to 52 patients with normal or impaired renal function: glomerular filtration rate (GFR)=0–133 ml/min. The serum concentration and urinary excretion of hydroxyproline were measured and the equivalent polypeptide concentrations were calculated from the results. In patients with normal renal function (GFR>90 ml/min) the proportion of polypeptide excreted in the urine up to 12 h was 45.4±2.6% ( $$\bar X$$ ±SEM), up to 24 h 47.7±2.9% and up to 48 h 49.3±3.4%. In patients with moderate renal insufficiency (GFR=30–90 ml/min) there was no decrease in polypeptide excretion and even in patients with more serious impairme…

medicine.medical_specialtyTime FactorsUrinary systemPlasma SubstitutesRenal functionUrine030204 cardiovascular system & hematologyurologic and male genital diseasesExcretion03 medical and health sciencesHydroxyprolinechemistry.chemical_compound0302 clinical medicinePharmacokineticsRenal Dialysis030202 anesthesiologyInternal medicinemedicineHumansPharmacology (medical)CyanatesPharmacologyChemistryHalf-lifeGeneral Medicine3. Good healthKineticsEndocrinologyKidney DiseasesPeptidesHaemaccelGlomerular Filtration RateHalf-LifeEuropean Journal of Clinical Pharmacology
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Chick embryo retina development in vitro: the effect of insulin.

1995

In this paper we study the development of chick embryo retina cultured in vitro and the effects exerted by insulin. Retinas were removed from 7-day embryos and cultured in serum- and hormone-free medium for 7 additional days. Under these conditions retinal cells survived and underwent cholinergic differentiation, as previously ascertained by Hausman et al. (Dev. Brain Res., 1991, 59: 31-37). However, a great retardation of development was noted compared to uncultured control, 14-day retina. In fact both wet weight and DNA and protein content increased much slower than in ovo and the tubulin content decreased below even the starting value. In addition, although after 7 days in culture retina…

medicine.medical_specialtyTime Factorsmedicine.medical_treatmentBlotting WesternChick EmbryoIn ovoBiochemistryCulture Media Serum-FreeRetinaCholine O-AcetyltransferaseCellular and Molecular Neurosciencechemistry.chemical_compoundParacrine signallingOrgan Culture TechniquesLeucineTubulinInternal medicinemedicineAnimalsInsulinAspartate AminotransferasesAutocrine signallingRetinabiologyDose-Response Relationship DrugInsulinEmbryoRetinalCell DifferentiationGeneral MedicineDNAInsulin receptorKineticsEndocrinologymedicine.anatomical_structurechemistryPhosphopyruvate HydrataseProtein Biosynthesisbiology.proteinThymidineNeurochemical research
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Learning curve for piezosurgery in well-trained otological surgeons

2009

Abstract Objective Piezosurgery is an ultrasound instrument (24.7-29.5 kHz) capable of cutting bone without necrosis and nonmineralized tissue damage. The aim of this work has been to determine the time required for a well-trained surgeon to perform otological surgery with the piezoelectric device. Study Design Case series with planned data collection. Sixty-three patients affected by otosclerosis and 63 by chronic otitis media were enrolled. For each disease, patients were divided into three numerically equal groups, with each group assigned to a well-trained otological surgeon. Patients underwent stapedotomy (n = 63) and intact canal wall tympanoplasty (n = 63) with the piezoelectric devi…

medicine.medical_specialtyTime Factorsmedicine.medical_treatmentUltrasonic TherapypiezosurgeryOtoacoustic emissionOsteotomyotologic surgerymedicineTrainingHumanspiezosurgery otologic surgeryChronic otitis mediaPiezosurgeryPiezosurgery; Otosclerosis; Chronic otitis media; Training; Surgerymedicine.diagnostic_testbusiness.industrypiezosurgery; otologic surgeryUltrasoundEquipment DesignTympanometryTympanoplastymedicine.diseaseSurgeryOtitis MediaSettore MED/31 - OtorinolaringoiatriaOtosclerosisOtorhinolaryngologyOtosclerosisSurgeryAudiometrybusiness
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Ultrasound observation of tissue fluid infiltration causing stridor in a woman undergoing shoulder arthroscopy

2012

Respiratory stridor developed rapidly during an interscalene brachial plexus block for shoulder arthroscopy in an obese woman. Extensive cervicothoracic edema due to tissue diffusion of the arthroscopic fluid was suspected. The outcome of patient after conservative management was satisfactory. We give a brief review of how this complication develops, the ultrasound findings, and briefly discuss similar cases.

medicine.medical_specialtyTissue fluidStridorCritical Care and Intensive Care MedicineArthroscopyEdemamedicineEdemaHumansRespiratory SoundsUltrasonographyShoulder arthroscopyShoulder JointInterscalene brachial plexus blockbusiness.industryUltrasoundMiddle Agedmedicine.diseaseSurgeryAnesthesiology and Pain MedicineFemalemedicine.symptomComplicationbusinessInfiltration (medical)NeckRevista Española de Anestesiología y Reanimación
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Three-dimensional transvaginal ultrasound in gynecological diagnosis

1999

medicine.medical_specialtyTransvaginal ultrasoundReproductive MedicineRadiological and Ultrasound Technologybusiness.industrymedicineObstetrics and GynecologyRadiology Nuclear Medicine and imagingGeneral MedicineRadiologybusinessSurgeryUltrasound in Obstetrics and Gynecology
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Imaging of hepatocellular carcinoma: a pilot international survey

2020

Purpose To perform an international survey on current practices in imaging-based surveillance, diagnosis, staging, and assessment of treatment response for HCC. Materials and methods Three themes were covered in this international survey: demographics of respondents and liver imaging expertise; imaging practices for screening, surveillance, diagnosis, staging, and assessment of treatment response for HCC; and diagnostic imaging systems used. Descriptive summaries were created. Results Of 151 respondents, 22.5% were from Asia, 6.0% from Europe, 19.9% from North America, 26.5% from South America, and 25.2% from Australasia; 57.0% respondents worked in academic and 34.4% in private or mixed se…

medicine.medical_specialtyTreatment responseCarcinoma HepatocellularDemographicsHepatocellular carcinomaUrologyContrast MediaComputed tomographyClinical practiceImaging030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesDiagnosismedicineMedical imagingHumansRadiology Nuclear Medicine and imagingMedical physicsUltrasonographyLiver imagingRadiological and Ultrasound Technologymedicine.diagnostic_testbusiness.industryLiver NeoplasmsGastroenterologyInternational surveymedicine.diseaseMagnetic Resonance ImagingStandardizationEurope030220 oncology & carcinogenesisHepatocellular carcinomaNorth AmericabusinessRegional differencesAbdominal Radiology
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Re: Clinical implementation of routine screening for fetal trisomies in the UK NHS: cell-free DNA test contingent on results from first-trimester com…

2016

medicine.medical_specialtyTrisomyPrenatal diagnosis030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinePregnancyPrenatal DiagnosismedicineHumansRadiology Nuclear Medicine and imagingGynecologyFetusPregnancy030219 obstetrics & reproductive medicineRoutine screeningRadiological and Ultrasound TechnologyMaternal Serum Screening TestsObstetricsbusiness.industryObstetrics and GynecologyDNAGeneral Medicinemedicine.diseaseTest (assessment)Pregnancy Trimester FirstReproductive MedicineCell-free fetal DNACombined testFemaleDown SyndromeChromosomes Human Pair 18businessMaternal Serum Screening TestsUltrasound in Obstetrics & Gynecology
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