Search results for "Lability"
showing 10 items of 802 documents
Naturally occurring hemolysins in the coelomic fluid of Holothuria polii delle chiaie (Echinodermata).
1979
Abstract The coelomic fluid of Holothuria polii D.Ch contains hemolytic activity against erythrocytes of several vertebrate species. The hemolytic potency depends upon calcium ion concentration and varies according to erythrocyte source and cell number in the reaction mixture. Absorption experiments with formalinized rabbit erythrocytes suggest that hemolytic activity is not specific. Its heat lability, water insolubility at low pH values, and sensitivity to proteolytic enzymes suggest that hemolytic activity resides in protein molecules. The activity, maximal in alkaline media, appears to depend up time and temperature.
Design of an exact data deduplication cluster
2012
Data deduplication is an important component of enterprise storage environments. The throughput and capacity limitations of single node solutions have led to the development of clustered deduplication systems. Most implemented clustered inline solutions are trading deduplication ratio versus performance and are willing to miss opportunities to detect redundant data, which a single node system would detect. We present an inline deduplication cluster with a joint distributed chunk index, which is able to detect as much redundancy as a single node solution. The use of locality and load balancing paradigms enables the nodes to minimize information exchange. Therefore, we are able to show that, …
A fault-tolerant protocol for railway control systems
2006
Railway control systems are largely based on data communication and network technologies. With the adoption of Ethernet-IP as the main technology for building end-to-end real-time networks on railway control systems, the requirement to deliver high availability, quality and secure services over Ethernet has become strategic. Critical real-time traffic is generally penalized and the maximum restoration time of 50 msec sometimes is exceeded because of real-time applications hangings, so passengers' safety could be committed. It occurs on more than twenty percent of critical fail tests performed. Our main goal is to minimize restoration time from the application point of view. This article des…
Polymeric microcontainers improve oral bioavailability of furosemide.
2016
Microcontainers with an inner diameter of 223 μm are fabricated using the polymer SU-8, and evaluated in vitro, in situ and in vivo for their application as an advanced oral drug delivery system for the poorly water soluble drug furosemide. An amorphous sodium salt of furosemide (ASSF) is filled into the microcontainers followed by applying a lid using Eudragit L100. It is possible to control the drug release in vitro, and in vitro absorption studies show that the microcontainers are not a hindrance for absorption of ASSF. In situ perfusion studies in rats are performed with ASSF-filled microcontainers coated with Eudragit and compared to a furosemide solution. The absorption rate constant …
Evaluating the impact of friends in predicting user’s availability in online social networks
2017
In recent years, Online Social Networks (OSNs) have changed the way people connect and interact with each other. Indeed, most people have registered an account on some popular OSNs (such as Facebook, or Google+) which is used to access the system at different times of the days, depending on their life and habits. In this context, understanding how users connect to the OSNs is of paramount importance for both the protection of their privacy and the OSN’s provider (or third-party applications) that want to exploit this information. In this paper, we study the task of predicting the availability status (online/offline) of the OSNs’ users by exploiting the availability information of their frie…
Performance of LoRa for Bike-Sharing Systems
2019
Today bike sharing systems are becoming popular in many cities as short-distance transit vehicles. More than 18 million bicycles are available worldwide for public use and one of the main problems that afflicts such sharing systems is the loss of bikes, which can be stolen or simply left in unknown locations. Thus, many bikes are docked or tracked using GPS and costly cellular connections. In this paper, we consider the emerging Long Range (LoRa) technology for use in bike sharing systems. LoRa exploits free ISM bands and has been conceived for low power and low data rate applications. Additionally, LoRa is characterized by large cells and heterogeneous application domains, which may lead t…
Improving prostate whole gland segmentation in t2-weighted MRI with synthetically generated data
2021
Whole gland (WG) segmentation of the prostate plays a crucial role in detection, staging and treatment planning of prostate cancer (PCa). Despite promise shown by deep learning (DL) methods, they rely on the availability of a considerable amount of annotated data. Augmentation techniques such as translation and rotation of images present an alternative to increase data availability. Nevertheless, the amount of information provided by the transformed data is limited due to the correlation between the generated data and the original. Based on the recent success of generative adversarial networks (GAN) in producing synthetic images for other domains as well as in the medical domain, we present…
Investigating Low Level Protocols for Wireless Body Sensor Networks
2016
The rapid development of medical sensors has increased the interest in Wireless Body Area Network (WBAN) applications where physiological data from the human body and its environment is gathered, monitored, and analyzed to take the proper measures. In WBANs, it is essential to design MAC protocols that ensure adequate Quality of Service (QoS) such as low delay and high scalability. This paper investigates Medium Access Control (MAC) protocols used in WBAN, and compares their performance in a high traffic environment. Such scenario can be induced in case of emergency for example, where physiological data collected from all sensors on human body should be sent simultaneously to take appropria…
Finding k -dissimilar paths with minimum collective length
2018
Shortest path computation is a fundamental problem in road networks. However, in many real-world scenarios, determining solely the shortest path is not enough. In this paper, we study the problem of finding k-Dissimilar Paths with Minimum Collective Length (kDPwML), which aims at computing a set of paths from a source s to a target t such that all paths are pairwise dissimilar by at least \theta and the sum of the path lengths is minimal. We introduce an exact algorithm for the kDPwML problem, which iterates over all possible s-t paths while employing two pruning techniques to reduce the prohibitively expensive computational cost. To achieve scalability, we also define the much smaller set …
Capture Aware Sequential Waterfilling for LoraWAN Adaptive Data Rate
2020
LoRaWAN (Long Range Wide Area Network) is emerging as an attractive network infrastructure for ultra low power Internet of Things devices. Even if the technology itself is quite mature and specified, the currently deployed wireless resource allocation strategies are still coarse and based on rough heuristics. This paper proposes an innovative "sequential waterfilling" strategy for assigning Spreading Factors (SF) to End-Devices (ED). Our design relies on three complementary approaches: i) equalize the Time-on-Air of the packets transmitted by the system's EDs in each spreading factor's group; ii) balance the spreading factors across multiple access gateways, and iii) keep into account the c…