Search results for "Large"
showing 10 items of 2197 documents
Spatial transcriptome of a germinal center plasmablastic burst hints at MYD88/CD79B mutants-enriched diffuse large B-cell lymphomas
2022
The GC reaction results in the selection of B cells acquiring effector Ig secreting ability by progressing toward plasmablastic differentiation. This transition is associated with exclusion from the GC microenvironment. The aberrant expansion of plasmablastic elements within the GC fringes configures an atypical condition, the biological characteristics of which have not been defined yet. We investigated the in situ immunophenotypical and transcriptional characteristics of a nonclonal germinotropic expansion of plasmablastic elements (GEx) occurring in the tonsil of a young patient. Compared to neighboring GC and perifollicular regions, the GEx showed a distinctive signature featuring key r…
Large-Eddy Simulation of Flow and Heat Transfer in Compact Heat Exchangers
1994
LES results are presented for different heat exchanger geometries. Subgrid terms were usually computed by the Smagorinsky model; preliminary comparative results are also given for the ‘dynamic’ subgrid model. The numerical methods used were those implemented in a commercial general-purpose code (CFDS-FLOW3D); they included a finite-volume approach, colocated body-fitted grids, central differencing for the advection terms, the SIMPLEC algorithm, and Crank-Nicolson time stepping. Predictions arc compared with experimental measurements (including local Nu distributions), and with results from a low-Reynolds number k-e model. In most cases, LES was more ‘robust’ and required little more CPU tim…
X-Ritz Solution for Nonlinear Free Vibrations of Plates with Embedded Cracks
2019
The analysis of large amplitude vibrations of cracked plates is considered in this study. The problem is addressed via a Ritz approach based on the first-order shear deformation theory and von Karman’s geometric nonlinearity assumptions. The trial functions are built as series of regular orthogonal polynomial products supplemented with special functions able to represent the crack behaviour (which motivates why the method is dubbed as eXtended Ritz); boundary functions are used to guarantee the fulfillment of the kinematic boundary conditions along the plate edges. Convergence and accuracy are assessed to validate the approach and show its efficiency and potential. Original results are then…
The ATHENA X-ray Integral Field Unit (X-IFU)
2018
Event: SPIE Astronomical Telescopes + Instrumentation, 2018, Austin, Texas, United States.
Development of a questionnaire to assay recalled liking for salt, sweet and fat
2012
Abstract Liking for a sweet, salty or fatty diet may induce overconsumption of simple carbohydrates, sodium or lipids. Measuring overall liking of the corresponding sensory sensations contributes to understanding the determinants of dietary behaviours. However, no standardized validated questionnaire assaying these sensations is currently available. In the present study, we developed a web-based questionnaire, “PrefQuest”, which measures recalled liking for the following four sensations: salt, fat and salt, sweet, fat and sweet. PrefQuest included four types of items: (1) liking for sweet, fatty-sweet and fatty-salty foods, (2) preferences in the level of seasoning by adding salt, sweetener…
New facets and an enhanced branch-and-cut for the min-max K -vehicles windy rural postman problem
2011
[EN] The min-max windy rural postman problem is a multiple vehicle version of the windy rural postman problem, WRPP, which consists of minimizing the length of the longest route to find a set of balanced routes for the vehicles. In a previous paper, an ILP formulation and a partial polyhedral study were presented, and a preliminary branch-and-cut algorithm that produced some promising computational results was implemented. In this article, we present further results for this problem. We describe several new facet-inducing inequalities obtained from the WRPP, as well as some inequalities that have to be satisfied by any optimal solution. We present an enhanced branch-and-cut algorithm that t…
Flow and Heat Transfer in Corrugated Passages: Direct and Large Eddy Simulation and Comparison with Experimental Results
1993
Direct and large-eddy numerical simulations are presented for the transitional and turbulent flow with heat transfer in corrugated passages, representative of compact heat exchangers such as rotary air preheaters (regenerators), at Reynolds number ranging from 103 to 104. Pressure drop and heat transfer results are compared with wind-tunnel experimental data; the agreement is quite satisfactory, and superior to that obtained by more traditional methods.
Measurement of upsilon production in 7 TeV pp collisions at ATLAS
2013
Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAM
Propeller Flaps: A Review of Indications, Technique, and Results
2014
In the last years, propeller flaps have become an appealing option for coverage of a large range of defects. Besides having a more reliable vascular pedicle than traditional flap, propeller flaps allow for great freedom in design and for wide mobilization that extend the possibility of reconstructing difficult wounds with local tissues and minimal donor-site morbidity. They also allow one-stage reconstruction of defects that usually require multiple procedures. Harvesting of a propeller flap requires accurate patient selection, preoperative planning, and dissection technique. Complication rate can be kept low, provided that potential problems are prevented, promptly recognized, and adequate…
Evaluation of the impact of therapeutic management on the survival and quality of life of patients with follicular lymphoma or diffuse large B cell l…
2014
In France, hematologic malignancies, which are the sixthmost common cancers, are amajor public healthproblem. This work aimed to study the impact of the therapeutic management on survival and healt-relatedquality of life (HRQoL) in patients with these hematologic malignancies. The first objective of this work is topresent an overview of the epidemiology of lymphoid malignancies with a study of changes in the incidenceand net survival in the Côte d’Or department between 1980 and 2009. The incidence, which has increased since1980, seems to have stabilized since the 2000s for some entities, including follicular lymphoma (FL) and diffuselarge B-cell lymphoma (DLBCL). Overall, we observed an imp…