Search results for "Large"
showing 10 items of 2197 documents
Ribosome Heterogeneity in Plant and Animal Organisms. Its Relationship to Ribosomal Ambiguity and to Ribosome Evolution
1970
Abstract The data presented and discussed in this report summarize evidence showing that ribosomes isolated from several eucaryotic (plant and animal) organisms exhibit ample variations of the composition of their protein moiety and that the degree of dissimilarity correlates with the degree of taxonomic kinship of the organisms from which the ribosomes were derived. They also provide evidence that (a) the 80-S ribosomes isolated from the cytoplasmic matrix of higher plants and yeast and the 70-S ribosomes derived from both chloroplasts and mitochondria are endowed with highly dissimilar protein complements, (b) the organellar (67-S) ribosomes derived from the chloroplasts of more or less d…
A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome
2010
Richter syndrome (RS) represents the transformation of chronic lymphocytic leukaemia (CLL) to aggressive lymphoma. Risk factors of CLL transformation to RS are only partly known. We explored the role of the host genetic background as a risk factor for RS occurrence. Forty-five single nucleotide polimorphisms (SNPs) known to be relevant for CLL prognosis were genotyped in a consecutive cohort of 331 CLL, of which 21 had transformed to RS. After correcting for multiple testing and adjusting for previously reported RS risk factors, the LRP4 rs2306029 TT variant genotype was the sole SNP independently associated with a higher risk of RS transformation (Hazard Ratio: 4·17; P = 0·001; q = 0·047).…
Antennas for the detection of radio emission pulses from cosmic-ray induced air showers at the Pierre Auger Observatory.
2012
The Pierre Auger Observatory is exploring the potential of the radio detection technique to study extensive air showers induced by ultra-high energy cosmic rays. The Auger Engineering Radio Array (AERA) addresses both technological and scientific aspects of the radio technique. A first phase of AERA has been operating since September 2010 with detector stations observing radio signals at frequencies between 30 and 80 MHz. In this paper we present comparative studies to identify and optimize the antenna design for the final configuration of AERA consisting of 160 individual radio detector stations. The transient nature of the air shower signal requires a detailed description of the antenna s…
Performance of jet substructure techniques for large-$R$ jets in proton-proton collisions at $\sqrt{s}$ = 7 TeV using the ATLAS detector
2013
This paper presents the application of a variety of techniques to study jet substructure. The performance of various modified jet algorithms, or jet grooming techniques, for several jet types and event topologies is investigated for jets with transverse momentum larger than 300 GeV. Properties of jets subjected to the mass-drop filtering, trimming, and pruning algorithms are found to have a reduced sensitivity to multiple proton-proton interactions, are more stable at high luminosity and improve the physics potential of searches for heavy boosted objects. Studies of the expected discrimination power of jet mass and jet substructure observables in searches for new physics are also presented.…
Structure Effect of Imidazolium-Based Dicationic Ionic Liquids on Claisen Rearrangement
2014
A large group of imidazolium-based dicationic ionic liquids (DILs) has been prepared in good yields. Thermal stability of all DILs has been determined. The effects of the reaction time, cation, imidazolium C2–H acidity, and anion on the Claisen rearrangement of allyl phenyl ether have been investigated. Type of anion and the presence of the acidic C2–H bond in the imidazolium moieties have proven to be essential for this reaction. The simple procedure and the possibility of avoiding the use catalysts and volatile organic solvents make this synthetic method environmentally benign and adaptable for large-scale applications.
Identifying individual differences using log-file analysis: Distributed learning as mediator between conscientiousness and exam grades
2018
Abstract Online learning poses major challenges on students' self-regulated learning. This study investigated the role of learning strategies and individual differences in cognitive abilities, high school GPA and conscientiousness for successful online learning. We used longitudinal log-file data to examine learning strategies of a large cohort (N = 424) of university students taking an online class. Distributed learning, the use of self-tests and a better high school GPA was associated with better exam grades. The positive effect of conscientiousness on exam grades was mediated by distributed learning. Conscientious students distributed their studying over the course of the semester, which…
Search for supersymmetry in events with large missing transverse momentum, jets, and at least one tau lepton in 7 TeV proton-proton collision data wi…
2012
A search for supersymmetry (SUSY) in events with large missing transverse momentum, jets, and at least one hadronically decaying τ lepton, with zero or one additional light lepton (e/μ), has been performed using 4.7 fb[superscript −1] of proton-proton collision data at √s = 7 TeV recorded with the ATLAS detector at the Large Hadron Collider. No excess above the Standard Model background expectation is observed and a 95 % confidence level visible cross-sectionupper limit for new phenomena is set. In the framework of gauge-mediated SUSY-breaking models, lower limits on the mass scale Λ are set at 54 TeV in the regions where the [bar over τ]1 is the next-to-lightest SUSY particle (tanβ > 20). …
On Fine and Wilf's theorem for bidimensional words
2003
AbstractGeneralizations of Fine and Wilf's Periodicity Theorem are obtained for the case of bidimensional words using geometric arguments. The domains considered constitute a large class of convex subsets of R2 which include most parallelograms. A complete discussion is provided for the parallelogram case.
Efficient formulation of a two-noded geometrically exact curved beam element
2021
The article extends the formulation of a 2D geometrically exact beam element proposed by Jirasek et al. (2021) to curved elastic beams. This formulation is based on equilibrium equations in their integrated form, combined with the kinematic relations and sectional equations that link the internal forces to sectional deformation variables. The resulting first-order differential equations are approximated by the finite difference scheme and the boundary value problem is converted to an initial value problem using the shooting method. The article develops the theoretical framework based on the Navier-Bernoulli hypothesis, with a possible extension to shear-flexible beams. Numerical procedures …
A symmetric tangent stiffness approach to cohesive mechanical interfaces in large displacements
2022
The present article proposes a formulation for a cohesive interface element in large displacement conditions. Theoretical and computational aspects, useful for an effective and efficient finite element implementation, are examined in details. A six-node (or higher) isoparametric interface element for two dimensional cohesive fracture propagation problems is developed. The element operators are consistently derived by a variational approach enforced in the current configuration, where a current frame is defined with axes tangential and normal to the middle line of the interface opening displacement gap. Under the constitutive assumption of small value of the modulus of the vector product bet…