Search results for "Lasers"

showing 10 items of 316 documents

The Greenland shark Somniosus microcephalus—Hemoglobins and ligand-binding properties

2017

A large amount of data is currently available on the adaptive mechanisms of polar bony fish hemoglobins, but structural information on those of cartilaginous species is scarce. This study presents the first characterisation of the hemoglobin system of one of the longest-living vertebrate species (392 +/- 120 years), the Arctic shark Somniosus microcephalus. Three major hemoglobins are found in its red blood cells and are made of two copies of the same a globin combined with two copies of three very similar beta subunits. The three hemoglobins show very similar oxygenation and carbonylation properties, which are unaffected by urea, a very important compound in marine elasmobranch physiology.…

---0301 basic medicinegenetic structuresProtein ConformationGreenlandlcsh:MedicineRESONANCE RAMAN-SPECTRAHETERODONTUS-PORTUSJACKSONISpectrum Analysis RamanBiochemistrychemistry.chemical_compoundHemoglobinsProtein structureAMINO-ACID SEQUENCEAnimal CellsSequence Analysis ProteinRed Blood CellsUreaNOTOTHENIOID FISHESPost-Translational Modificationlcsh:ScienceHemeChondrichthyesMultidisciplinarybiologyChemistryOrganic CompoundsChemical ReactionsVertebrateEukaryotaMOLECULAR ADAPTATIONSMicrocephalusGlobinsChemistryBiochemistryOptical EquipmentVertebratesPhysical SciencesEngineering and TechnologyCellular TypesResearch ArticleEnvironmental MonitoringProtein BindingQUATERNARY STRUCTURESAllosteric regulationEquipmentSTRETCHING FREQUENCIESHeme03 medical and health sciencesOXYGEN-BINDINGbiology.animalAnimals14. Life underwaterGlobinHemoglobinPhotolysisBlood Cells030102 biochemistry & molecular biologyLaserslcsh:ROrganic ChemistryOrganismsChemical CompoundsBiology and Life SciencesProteinsxxxCell Biologybiology.organism_classificationCARTILAGINOUS FISHOxygen030104 developmental biologySomniosusFishSharkslcsh:QHemoglobinProtein MultimerizationELASMOBRANCH HEMOGLOBINElasmobranchiiPLoS ONE
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Optimisation of refractory coatings realised with cored wire addition using a high-power diode laser

2005

Laser; Cladding; Refractory alloys; Factorial experiments; International audience; The objective or our research was to obtain refractory alloys using the high-power diode laser (HPDL) coating technique. After optimisation using factorial experiments, two different cladding regimes were clearly distinguished. It was also shown that a very narrow transition zone exists between the two regimes, and, inside this zone, clad layers having a satisfactory compromise between the response functions (surface aspect and cavity presence) were obtained. The main objective of our study, namely, the control of the operating parameters (geometrical and kinematical) to realise adequate coatings, without cav…

0209 industrial biotechnologyMaterials science[ PHYS.COND.CM-MS ] Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]02 engineering and technologyWeldingengineering.materiallaw.invention020901 industrial engineering & automationCoatinglawMaterials ChemistryComposite materialDiodeHigh power lasersSurfaces and InterfacesGeneral ChemistryFactorial experiment021001 nanoscience & nanotechnologyCondensed Matter PhysicsLaserCladding (fiber optics)Surfaces Coatings and FilmsPower diodeengineering[PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]0210 nano-technology
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Antimicrobial photodynamic therapy using diode laser activated indocyanine green as an adjunct in the treatment of chronic periodontitis: A randomize…

2016

Abstract Introduction Clinical studies have shown the usefulness of antimicrobial photodynamic therapy (aPDT) as an adjunctive in periodontal therapy. These studies did not utilize indocyanine green (ICG) as a recently introduced photosensitizer. The aim of this study was to perform a full-mouth double-blind randomized controlled clinical study to test the efficacy of adjunctive aPDT with ICG compared with scaling and root planing (SRP) alone in chronic periodontitis treatment. Materials and methods Fifty patients were selected for this study. All patients received SRP. Then, each patient was randomly assigned to either the test group (aPDT + SRP) or the control group (SRP). aPDT was perfor…

0301 basic medicineAdultIndocyanine GreenMale030103 biophysicsGingival and periodontal pocketmedicine.medical_treatmentBleeding on probingBiophysicsDentistryPhotodynamic therapyDermatologylaw.invention03 medical and health scienceschemistry.chemical_compound0302 clinical medicineScaling and root planingRandomized controlled triallawmedicineHumansPharmacology (medical)Photosensitizing Agentsbusiness.industryReproducibility of Results030206 dentistryMiddle AgedReference Standardsmedicine.diseaseChronic periodontitisOncologychemistryClinical attachment lossPhotochemotherapyChronic PeriodontitisFemalemedicine.symptomLasers SemiconductorbusinessIndocyanine greenPhotodiagnosis and photodynamic therapy
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Generation and Coherent Control of Pulsed Quantum Frequency Combs

2018

We present a method for the generation and coherent manipulation of pulsed quantum frequency combs. Until now, methods of preparing high-dimensional states on-chip in a practical way have remained elusive due to the increasing complexity of the quantum circuitry needed to prepare and process such states. Here, we outline how high-dimensional, frequency-bin entangled, two-photon states can be generated at a stable, high generation rate by using a nested-cavity, actively mode-locked excitation of a nonlinear micro-cavity. This technique is used to produce pulsed quantum frequency combs. Moreover, we present how the quantum states can be coherently manipulated using standard telecommunications…

0301 basic medicineDensity matrixOptics and PhotonicsPhotonGeneral Chemical EngineeringSettore ING-INF/01 - ElettronicaGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesEngineering0302 clinical medicineQuantum stateQuantum DotsQuantumQCQuantum opticsPhysicsGeneral Immunology and Microbiologybusiness.industryGeneral NeuroscienceNonlinear opticsSettore ING-INF/02 - Campi Elettromagnetici030104 developmental biologyCoherent controlQuantum optics Integrated photonic devices Mode-locked lasers Nonlinear optics Four-wave mixing Frequency combs High- dimensional statesFrequency domainOptoelectronicsbusiness030217 neurology & neurosurgeryJournal of Visualized Experiments
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Early adjustment of empirical antibiotic therapy of bloodstream infections on the basis of direct identification of bacteria by matrix-assisted laser…

2020

Abstract Introduction To assess the potential added value of rapid MALDI-TOF MS-based identification of bacteria in positive blood cultures to the information provided by Gram staining for adequate empirical antibiotic treatment adjustments in patients with bloodstream infections (BSI). Methods We conducted a retrospective, single-center, pre-post quasi-experimental study. In the pre-MALDI-TOF MS phase of the study antibiotic adjustments were made on the basis of Gram stain results, whereas in the MALDI-TOF MS phase they were based on information provided by Gram staining and MALDI-TOF MS results. No antimicrobial stewardship program for BSI was in place within the study period. Antibiotic …

0301 basic medicineMicrobiology (medical)EnterobacterialesBacillimedicine.medical_specialtymedicine.drug_class030106 microbiologyAntibioticsBacteremialaw.invention03 medical and health sciences0302 clinical medicinelawSepsisInternal medicinemedicineHumansAntimicrobial stewardshipPharmacology (medical)Blood culture030212 general & internal medicineRetrospective StudiesBacteriaStaining and Labelingbiologymedicine.diagnostic_testbusiness.industryLasersbiology.organism_classificationmedicine.diseaseAnti-Bacterial AgentsInfectious DiseasesGram stainingSpectrometry Mass Matrix-Assisted Laser Desorption-IonizationBacteremiabusinessBacteriaJournal of Infection and Chemotherapy
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Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein

2016

Many biological processes depend on detecting and responding to light. The response is often mediated by a structural change in a protein that begins when absorption of a photon causes isomerization of a chromophore bound to the protein. Pande et al. used x-ray pulses emitted by a free electron laser source to conduct time-resolved serial femtosecond crystallography in the time range of 100 fs to 3 ms. This allowed for the real-time tracking of the trans-cis isomerization of the chromophore in photoactive yellow protein and the associated structural changes in the protein.Science, this issue p. 725A variety of organisms have evolved mechanisms to detect and respond to light, in which the re…

0301 basic medicinePhotoreceptorsTime FactorsPhotoisomerizationLightProtein ConformationPhotochemistryPhotoreceptors MicrobialMYOGLOBINProtein structureMicrobialX-RAY-DIFFRACTIONPHOTOISOMERIZATIONMOTIONSchromophoresta116MultidisciplinarySPECTROSCOPYCrystallographyChemistryPhotochemical ProcessesTime resolved crystallographyTIMEMultidisciplinary SciencesPicosecondFemtosecondphotoactive proteinsScience & Technology - Other Topicsddc:500IsomerizationStereochemistryGeneral Science & TechnologyConjugated systemArticle03 medical and health sciencesBacterial ProteinsIsomerismEXCITATIONx-ray crystallographyPhotonsScience & TechnologyPHOTOCYCLEta114CHROMOPHOREta1182PATHWAYSChromophore030104 developmental biologyfree-electron laserssense organstrans-cis isomerization
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Ultrafast structural changes within a photosynthetic reaction centre

2021

Nature <London> / Physical science 589, 310 - 314 (2021). doi:10.1038/s41586-020-3000-7

0301 basic medicinePhotosynthetic reaction centreChlorophyllModels MolecularklorofylliCytoplasmUbiquinonePhotosynthetic Reaction Center Complex ProteinsElectrons02 engineering and technologyPhotochemistrymedicine.disease_cause530yhteyttäminenbakteeritElectron Transport03 medical and health sciencesElectron transfermedicineMoleculeddc:530BacteriochlorophyllsbioenergetiikkaComputingMilieux_MISCELLANEOUSHyphomicrobiaceaeMultidisciplinaryBinding SitesCrystallography[SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry Molecular Biology/Structural Biology [q-bio.BM]ChemistryBlastochloris viridisLaserskalvot (biologia)PheophytinsBiological membraneVitamin K 2021001 nanoscience & nanotechnologyAcceptor030104 developmental biologyPicosecondFemtosecondsense organsProtons0210 nano-technologyOxidation-Reductionröntgenkristallografia
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Confocal scanning laser ophthalmoscopy versus modified conventional fundus camera for fundus autofluorescence.

2016

Fundus autofluorescence (FAF) is a noninvasive imaging method to detect fundus endogenous fluorophores, mainly lipofuscin located in the retinal pigment epithelium (RPE). The FAF provides information about lipofuscin distribution and RPE health, and consequently an increased accumulation of lipofuscin has been correlated with ageing and development of certain retinal conditions. Areas covered: An exhaustive literature search in MEDLINE (via OVID) and PUBMED for articles related to ocular FAF in retinal diseases and different devices used for acquiring FAF imaging was conducted. Expert commentary: This review aims to show an overview about autofluorescence in the RPE and the main devices use…

0301 basic medicinemedicine.medical_specialtygenetic structuresFundus OculiBiomedical EngineeringFundus (eye)Fundus cameraFluorescenceLipofuscin03 medical and health scienceschemistry.chemical_compound0302 clinical medicineOpticsOphthalmologymedicinePhotographyHumansFluorescent DyesRetinal pigment epitheliumbusiness.industryLasersRetinalGeneral Medicineeye diseasesFundus autofluorescenceConfocal scanning laser ophthalmoscopyOphthalmoscopyAutofluorescence030104 developmental biologymedicine.anatomical_structurechemistry030221 ophthalmology & optometrySurgerysense organsbusinessExpert review of medical devices
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Nonlinear femtosecond pulse propagation in an all-solid photonic bandgap fiber

2009

Nonlinear femtosecond pulse propagation in an all-solid photonic bandgap fiber is experimentally and numerically investigated. Guiding light in such fiber occurs via two mechanisms: photonic bandgap in the central silica core or total internal reflection in the germanium doped inclusions. By properly combining spectral filtering, dispersion tailoring and pump coupling into the fiber modes, we experimentally demonstrate efficient supercontinuum generation with controllable spectral bandwidth.

060.2400;190.4370Materials scienceOptical fiberPhysics::OpticsPolarization-maintaining optical fiber02 engineering and technologySensitivity and Specificity01 natural sciences7. Clean energyGraded-index fiberlaw.invention010309 opticsCondensed Matter::Materials Science020210 optoelectronics & photonicsOpticslaw0103 physical sciences0202 electrical engineering electronic engineering information engineeringScattering RadiationDispersion-shifted fiberNonlinear Sciences::Pattern Formation and SolitonsOptical FibersPhotonic crystalPhotonsbusiness.industryLasersReproducibility of ResultsSignal Processing Computer-AssistedEquipment DesignMicrostructured optical fiberAtomic and Molecular Physics and OpticsSupercontinuumEquipment Failure AnalysisNonlinear DynamicsComputer-Aided DesignOptoelectronicsbusinessElectromagnetic pulse; energy gap; fibersPhotonic-crystal fiber
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Porous 3D Printed Scavenger Filters for Selective Recovery of Precious Metals from Electronic Waste

2018

Selective laser sintering (SLS) 3D printing is used to fabricate highly macroporous ion scavenger filters for recovery of Pd and Pt from electronic waste. The scavengers are printed by using a mixture of polypropylene with 10 wt% of type‐1 anion exchange resin. Porosities and the flow‐through properties of the filters are controlled by adjusting the SLS printing parameters. The cylinder‐shaped filters are used in selective recovery of Pd and Pt from acidic leachate of electronic waste simply by passing the solution through the object. Under such conditions, the scavenger filters are able to capture Pd and Pt as anionic complexes with high efficiency from a solution containing mixture of dif…

3d printedMaterials science3D printing02 engineering and technology010402 general chemistry01 natural sciences7. Clean energyElectronic wastelaw.inventionelectronic wastejalometallitsuodattimetlaw3D-tulostusmetallitPorosityta116General Environmental SciencesintrausRenewable Energy Sustainability and the Environmentbusiness.industryprecious metals021001 nanoscience & nanotechnologyporous 3D printed scavenger filtersScavenger (chemistry)0104 chemical sciencesSelective laser sinteringChemical engineeringtalteenottoSelektiivinen lasersintraus (SLS)sähkö- ja elektroniikkaromu0210 nano-technologybusiness
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