Search results for "Lava"

Neurotrophic Properties of Silexan, an Essential Oil from the Flowers of Lavender-Preclinical Evidence for Antidepressant-Like Properties.

2020

Abstract Background Silexan, a special essential oil from flowering tops of lavandula angustifolia, is used to treat subsyndromal anxiety disorders. In a recent clinical trial, Silexan also showed antidepressant effects in patients suffering from mixed anxiety-depression (ICD-10 F41.2). Since preclinical data explaining antidepressant properties of Silexan are missing, we decided to investigate if Silexan also shows antidepressant-like effects in vitro as well as in vivo models. Methods We used the forced swimming test (FST) in rats as a simple behavioral test indicative of antidepressant activity in vivo. As environmental events and other risk factors contribute to depression through conve…

Murine model of interstitial cytomegalovirus pneumonia in syngeneic bone marrow transplantation: persistence of protective pulmonary CD8-T-cell infil…

2000

ABSTRACTInterstitial pneumonia (IP) is a severe organ manifestation of cytomegalovirus (CMV) disease in the immunocompromised host, in particular in recipients of bone marrow transplantation (BMT). Diagnostic criteria for the definition of CMV-IP include clinical evidence of pneumonia together with CMV detected in bronchoalveolar lavage or lung biopsy. We have used the model of syngeneic BMT and simultaneous infection of BALB/c mice with murine CMV for studying the pathogenesis of CMV-IP by controlled longitudinal analysis. A disseminated cytopathic infection of the lungs with fatal outcome was observed only when reconstituting CD8 T cells were depleted. Neither CD8 nor CD4 T cells mediated…

Bronchoalveolar Lavage and Oleic Acid-Injection in Pigs as a Double-Hit Model for Acute Respiratory Distress Syndrome (ARDS).

2020

The treatment of ARDS continues to pose major challenges for intensive care physicians in the 21st century with mortality rates still reaching up to 50% in severe cases. Further research efforts are needed to better understand the complex pathophysiology of this disease. There are different well-established animal models to induce acute lung injury but none has been able to adequately mimic the complex pathomechanisms of ARDS. The most crucial factor for the development of this condition is the damage to the alveolar capillary unit. The combination of two well-established lung injury models allow us to mimic in more detail the underlying pathomechanism. Bronchoalveolar lavage (BAL) leads to…

Induction of accessory cell function of human alveolar macrophages by inhalation of human natural interleukin-2.

1996

Accessory function allows antigen-presenting cells to produce sufficient secondary signals for optimum T cell proliferation and interleukin-2 (IL-2) production. Alveolar macrophages are inferior accessory cells compared to monocytes (PBM). We report here that the accessory index (AI) of alveolar macrophages and PBM of patients with lung metastases of solid tumors treated with inhalations of human natural IL-2 (hnIL-2) increased following its administration (P0.005). The accessory index was significantly elevated from baseline values after 2 weeks of inhalation of 300,000 IU hnIL-2/day (8.2 +/- 10.2 compared to 1.1 +/- 1; P0.001). The inhalation of 150,000 IU also induced increases in the in…

A late Precambrian (∼ 710 Ma) high volcanicity rift in the southern Eastern Desert of Egypt

1991

The late Precambrian Shadli Metavolcanics of SE Egypt constitute a slightly metamorphosed bimodal sequence that has been previously interpreted as manifesting volcanic activity at an island arc. We report the first Rb-Sr geochronologic, trace element (including REE), and Nd isotopic data for these rocks. Two types of basalt are recognized, the stratigraphically lower suite having compositions like N-MORB ferrobasalt while the overlying basalt is similar to slightly fractionated E-MORB. The two basalt types were derived from melting of a strongly depleted source, most likely within the upper 60–75 km of the upper mantle. The origin of the felsic melts is problematic, and these could either h…

Darbības vārds Krāslavas, Aulejas, Skaistas un Izvaltas izloksnē

1993

Advisor: Rudzīte, Marta

Zvaigžņotā Debess: 2017, Vasara (236)

2017

Contents: In MEMORIAM of ANDREJS ALKSNIS: Curriculum Vitae of Andrejs Alksnis (1928-2017) ; Condolences and Parting Words ; List of Publications by Professor Andrejs Alksnis ; “ZVAIGŽŅOTĀ DEBESS” FORTY YEARS AGO: J.Francmanis. Enigma of Saturn’s Rings Brightness (abridged) ; E.Mūkins. Crater on Mercury Named After Rainis (abridged) ; Ā.Alksne. The Starry Sky in the Summer of 1977 (abridged) ; DEVELOPMENTS in SCIENCE: K.Schwartz. Early Universe Through the Eyes of Telescopes ; DISCOVERIES: K.Schwartz. Dwarf Galaxy Henize 2-10 with a Massive Black Hole ; J.Kuzmanis. Hot Topic – FRB 121102 ; SPACE RESEARCH and EXPLORATION: J.Kalvāns. Are Earth's Oceans of Interstellar Origin? ; J.Jaunbergs. ‘D…

Zvaigžņotā Debess: 60.gadskārta

2019

Contents: In Remembrance of Jānis Ikaunieks, Arturs Balklavs and Andrejs Alksnis: I.Pundure. «ZVAIGŽŅOTĀ DEBESS» Was Leading to the Truth … ; I.Pundure. Astronomers of Latvian Origin in IAU Management ; DISCOVERIES: I.Pundure. Gaia’s Most Accurate Star Map of Milky Way and Its Surroundings ; SPACE RESEARCH and EXPLORATION: I.Pundure. ESA Selects Three New Missions to Explore the Universe ; LATVIAN SCIENTISTS: The List of Popular Science Papers (1958-2016) by Professor Andrejs Alksnis (concluded) ; In memoriam: Dr.sc.ing. Edgars Bervalds (1936-2019) ; In memoriam: Dr.phys. Natālija Cimahoviča (1926-2019) ; FLASHBACK: I.Pundure. On Hawking’s Publication in the Vatican’s Commentarii Series ; F…

Kalmbergin kartasto R Va : List 4

1856

Proleg

2008

Sull'opera di A.E. Solàa come traduttore in lingua catalana del poeta greco C.P:Kavafis, e in particolare delle sue poesie incompiute edite da R.Lavagnini