Search results for "Lavandula"

showing 10 items of 34 documents

Dynamics of Monoterpene Formation in Spike Lavender Plants

2017

The metabolic cross-talk between the mevalonate (MVA) and the methylerythritol phosphate (MEP) pathways was analyzed in spike lavender (Lavandula latifolia Med) on the basis of 13CO2-labelling experiments using wildtype and transgenic plants overexpressing the 3-hydroxy-3-methylglutaryl CoA reductase (HMGR), the first and key enzyme of the MVA pathway. The plants were labelled in the presence of 13CO2 in a gas chamber for controlled pulse and chase periods of time. GC/MS and NMR analysis of 1,8-cineole and camphor, the major monoterpenes present in their essential oil, indicated that the C5-precursors, isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) of both monoterpenes …

0106 biological sciences0301 basic medicineLavenderEndocrinology Diabetes and MetabolismMonoterpeneLavandula latifolialcsh:QR1-502Reductase01 natural sciencesBiochemistryArticlelcsh:Microbiologylaw.inventionessential oils; isotopologue profiling; lamiaceae; <i>Lavandula latifolia</i>; spike lavender; terpenoid biosynthesis; mevalonate; CO<sub>2</sub>terpenoid biosynthesislamiaceae03 medical and health sciencesCamphorchemistry.chemical_compoundmevalonatelawMolecular Biologyessential oilsEssential oilchemistry.chemical_classificationbiologyChemistrybiology.organism_classificationddc:spike lavender030104 developmental biologyEnzymeisotopologue profilingBiochemistryLamiaceaeCO2Lavandula latifolia010606 plant biology & botanyMetabolites
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Phytotoxic Effects of Commercial Eucalyptus citriodora, Lavandula angustifolia, and Pinus sylvestris Essential Oils on Weeds, Crops, and Invasive Spe…

2019

Background: essential oils are well known for their pharmacological effectiveness as well as their repellent, insecticide, and herbicide activities. The emergence of resistant weeds, due to the overuse of synthetic herbicides, makes it necessary to find natural alternatives for weed control. The aim of this study was to evaluate the phytotoxic effects of Eucalyptus citriodora, Lavandula angustifolia, and Pinus sylvestris, three common commercial essential oils, on weeds (Portulaca oleracea, Lolium multiflorum, and Echinochloa crus-galli), food crops (tomato and cucumber), and the invasive species Nicotiana glauca. Methods: to determine herbicidal effects, essential oils were tested at diffe…

0106 biological sciencesE. citriodoraPlant WeedsPharmaceutical Sciencephytotoxicity<i>E. citriodora</i>01 natural sciencesAnalytical Chemistrylaw.inventionlawDrug DiscoveryRadicleGC–MSLavandula angustifoliaEucalyptusbiologyfood and beveragesPinus sylvestris<i>L. angustifolia</i>HorticultureLavandulaChemistry (miscellaneous)GerminationEucalyptus citriodoraMolecular MedicineCrops AgriculturalWeed ControlGerminationL. angustifoliaArticleGas Chromatography-Mass Spectrometrylcsh:QD241-441lcsh:Organic chemistryP. sylvestrisOils VolatilePhysical and Theoretical Chemistryessential oilsEssential oil<i>P. sylvestris</i>HerbicidesfungiOrganic ChemistryLolium multiflorumbiology.organism_classification0104 chemical sciences010404 medicinal & biomolecular chemistrySeedlingsSeedlingIntroduced SpeciesWeed010606 plant biology & botanyMolecules
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Essential Oils Extracted from Different Species of the Lamiaceae Plant Family as Prospective Bioagents against Several Detrimental Pests

2020

On the basis of the side effects of detrimental synthetic chemicals, introducing healthy, available, and effective bioagents for pest management is critical. Due to this circumstance, several studies have been conducted that evaluate the pesticidal potency of plant-derived essential oils. This review presents the pesticidal efficiency of essential oils isolated from different genera of the Lamiaceae family including Agastache Gronovius, Hyptis Jacquin, Lavandula L., Lepechinia Willdenow, Mentha L., Melissa L., Ocimum L., Origanum L., Perilla L., Perovskia Kar., Phlomis L., Rosmarinus L., Salvia L., Satureja L., Teucrium L., Thymus L., Zataria Boissier, and Zhumeria Rech. Along with acute to…

0106 biological sciencesfood.ingredientHyptisLavandulaPhytochemicalsPharmaceutical ScienceReviewacute toxicitysublethal effectsSatureja01 natural sciencesRosmarinusessential oilAnalytical Chemistrylaw.inventionTeucriumlcsh:QD241-441foodlcsh:Organic chemistrylawDrug DiscoveryOils Volatilesublethal effectPesticidesPhysical and Theoretical ChemistrymonoterpenoidsEssential oilLamiaceaeMolecular StructurebiologyTraditional medicineOrganic ChemistryOriganumbiology.organism_classification010602 entomologyChemistry (miscellaneous)Insect RepellentsSettore BIO/03 - Botanica Ambientale E ApplicataMolecular MedicineLamiaceae010606 plant biology & botanyMolecules
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Pharmacological basis of the anxiolytic and antidepressant properties of Silexan®, an essential oil from the flowers of lavender.

2021

Silexan®, a proprietary essential oil manufactured by steam distillation from Lavandula angustifolia flowers showed pronounced anxiolytic effects in patients with subthreshold anxiety disorders and was also efficacious in patients with Generalized Anxiety disorder (GAD). Moreover, evidences for antidepressant-like properties of Silexan® have been observed in anxious patients suffering from comorbid depressive symptoms and in patients with mixed anxiety-depression disorder (ICD-10 F41.2). In accordance with the clinical data Silexan® is active in several behavioral models in rodents at rather low concentrations indicating potent anxiolytic and antidepressive properties. As possible mechanism…

0301 basic medicineMAPK/ERK pathwayGeneralized anxiety disordermedicine.drug_classPregabalinFlowersPharmacologyAnxietyCREBAnxiolytic03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicinemedicineOils VolatileAnimalsHumansPlant OilsbiologyVoltage-dependent calcium channelChemistryDepressionCell Biologymedicine.diseaseCalcium Channel BlockersAntidepressive Agents030104 developmental biologyLavandulaMechanism of actionAnti-Anxiety Agentsbiology.proteinAntidepressantCalcium Channelsmedicine.symptom030217 neurology & neurosurgerymedicine.drugNeurochemistry international
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Bioactivity of essential oils in phytopathogenic and post-harvest fungi control

2017

[EN] Commercial thyme and lavender essential oils were analysed by GC/MS. Sixty-six compounds accounting for 98.6¿99.6% of total essential oil were identified. Thymol (52.14 ± 0.21%), followed by pcymene (32.24 ± 0.16%), carvacrol (3.71 ± 0.01%) and ¿-terpinene (3.34 ± 0.02%), were the main compounds in thyme essential oil, while large amounts of oxygenated monoterpenes linalool acetate (37.07 ± 0.24%) and linalool (30.16 ± 0.06%) were found in lavender one. In vitro antifungal activity of the essential oils was evaluated at 200 and 300 ¿g/mL against 10 phytopathogenic and post-harvest fungi, which significantly affect agriculture. Micelial growth inhibition was calculated for each tested f…

AntifungalLavendermedicine.drug_classAcyclic MonoterpenesBOTANICAPlant ScienceFungusCyclohexane MonoterpenesMicrobial Sensitivity Tests01 natural sciencesBiochemistryGas Chromatography-Mass SpectrometryAnalytical Chemistrylaw.inventionThymus Plantchemistry.chemical_compoundLinaloollawLavenderBotanymedicineOils VolatilePlant OilsCarvacrolFood scienceAntifungal activityThymolEssential oilBIOLOGIA VEGETALbiology010405 organic chemistryOrganic ChemistryFungiThymebiology.organism_classificationThymol0104 chemical sciencesFungicides Industrial010404 medicinal & biomolecular chemistryLavandulachemistryEssential oilsMonoterpenesCymenesGrowth inhibition
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Plant regeneration from isolated cells ofLavandula latifolia medicus

1988

Single cells were obtained from hypocotyl-derived callus ofLavandula latifolia Medicus. Cells were plated in Murashige and Skoog medium supplemented with indoleacetic acid (IAA), benzyladenine (BA), and several IAA-BA combinations. Cell division required the simultaneous presence of IAA and BA in the culture medium, but callus formation was only achieved with 0.1 or 1 mg/liter IAA and 2 mg/liter BA. To induce organogenesis, calli were transferred to various regeneration media. Shoot-bud differentiation efficiency depended on the composition of both the callus induction and the shoot regeneration media, best results being obtained when calli grown in 1 mg/liter IAA and 2 mg/liter BA were sub…

Callus formationClinical BiochemistryLavandula latifoliaOrganogenesisPlant ScienceCell BiologyBiologybiology.organism_classificationMurashige and Skoog mediumCell cultureCallusShootBotanyComposition (visual arts)BiotechnologyDevelopmental BiologyIn Vitro Cellular &amp; Developmental Biology
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Lavandula angustifolia Essential Oil and Linalool Counteract Social Aversion Induced by Social Defeat

2018

Many vegetable extracts, essential oils, and their main constituents are active on the Central Nervous System (CNS). In fact, they have been used as sedatives, hypnotics, or tranquilizers for their activity in treating CNS disorders. In this research, we studied the possible activities of Lavandula angustifolia (LA) essential oil and of its main constituent, linalool, as anti-stress compounds on anxiety and social interaction and their in vitro effects on proteins (pERK and PKA) involved in the transmission of the signal. An acute intraperitoneal injection of linalool (100 mg/kg) and of LA essential oil (200 mg/kg) reduced motor activity without any anxiolytic effect, but significantly incr…

Central Nervous System30030301 basic medicinelinaloolLavandulaVolatilePharmaceutical SciencePharmacologyAnalytical Chemistrylaw.inventionSocial defeatMicechemistry.chemical_compound0302 clinical medicineAnti-Anxiety AgentsLinaloolCentral Nervous System Diseasessocial defeatlawDrug DiscoveryHypnotics and SedativesEssential oil; Lavandula angustifolia; Linalool; Social defeat; Animals; Anti-Anxiety Agents; Antidepressive Agents; Central Nervous System; Central Nervous System Diseases; Humans; Hypnotics and Sedatives; Interpersonal Relations; Lavandula; Mice; Monoterpenes; Oils Volatile; Analytical Chemistry; Chemistry (miscellaneous); Molecular Medicine; 3003; Drug Discovery3003 Pharmaceutical Science; Physical and Theoretical Chemistry; Organic ChemistryLavandula angustifolia<i>Lavandula angustifolia</i>Antidepressive AgentsLavandulaChemistry (miscellaneous)Molecular MedicineAntidepressantmedicine.drug_classAnxiolyticArticleessential oillcsh:QD241-44103 medical and health scienceslcsh:Organic chemistrymedicineAnimalsHumansInterpersonal RelationsPhysical and Theoretical ChemistryEssential oilbusiness.industryDrug Discovery3003 Pharmaceutical ScienceOrganic Chemistry030104 developmental biologyAnti-Anxiety AgentschemistryLavandula angustifoliaMonoterpenesbusinessOils030217 neurology & neurosurgeryMolecules
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Up-regulation of 1-deoxy-D-xylulose-5-phosphate synthase enhances production of essential oils in transgenic spike lavender.

2006

Abstract Spike lavender (Lavandula latifolia) is an aromatic shrub cultivated worldwide for the production of essential oils. The major constituents of these oils are monoterpenes, which are obtained from isopentenyl diphosphate and dimethylallyl diphosphate precursors through the plastidial methylerythritol phosphate (MEP) pathway and/or the cytosolic mevalonate pathway. 1-Deoxy-d-xylulose-5-P synthase (DXS) catalyzes the first step of the MEP pathway. A cDNA coding for the Arabidopsis (Arabidopsis thaliana) DXS was constitutively expressed in spike lavender. Gas chromatography/mass spectrometry analyses revealed that transgenic plants accumulated significantly more essential oils compared…

ChlorophyllPhysiologyTransgeneMolecular Sequence DataLavandula latifoliaPlant ScienceGenetically modified cropslaw.inventionlawGene Expression Regulation PlantTransferasesArabidopsisBotanyGeneticsOils VolatileArabidopsis thalianaEssential oilbiologyATP synthasefood and beveragesbiology.organism_classificationPlants Genetically ModifiedCarotenoidsUp-RegulationPlant LeavesLavandulaBiochemistrybiology.proteinMevalonate pathwayResearch ArticlePlant physiology
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Deoxyxylulose 5-phosphate reductoisomerase is not a rate-determining enzyme for essential oil production in spike lavender

2014

[EN] Spike lavender (Lavandula latifolia) is an economically important aromatic plant producing essential oils, whose components (mostly monoterpenes) are mainly synthesized through the plastidial methylerythritol 4-phosphate (MEP) pathway. 1-Deoxy-d-xylulose-5-phosphate (DXP) synthase (DXS), that catalyzes the first step of the MEP pathway, plays a crucial role in monoterpene precursors biosynthesis in spike lavender. To date, however, it is not known whether the DXP reductoisomerase (DXR), that catalyzes the conversion of DXP into MEP, is also a rate-limiting enzyme for the biosynthesis of monoterpenes in spike lavender. To investigate it, we generated transgenic spike lavender plants con…

ChlorophyllPhysiologyTransgeneMonoterpeneLavandula latifoliaMonoterpeneGene ExpressionFlowersPlant ScienceEssential oillaw.inventionchemistry.chemical_compoundBiosynthesisTransferaseslawBIOQUIMICA Y BIOLOGIA MOLECULAROils VolatilePlant OilsArabidopsis thalianaAldose-Ketose IsomerasesEssential oilPlant ProteinsATP synthasebiologyArabidopsis ProteinsDXR enzymeDXS enzymeSpike lavenderPlants Genetically Modifiedbiology.organism_classificationCarotenoidsDXP reductoisomerasePlant LeavesErythritolLavandulaPhenotypechemistryBiochemistryMonoterpenesbiology.proteinSugar PhosphatesAgronomy and Crop ScienceJournal of Plant Physiology
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Up-regulation of an N-terminal truncated 3-hydroxy-3-methylglutaryl CoA reductase enhances production of essential oils and sterols in transgenic Lav…

2007

Spike lavender (Lavandula latifolia) essential oil is widely used in the perfume, cosmetic, flavouring and pharmaceutical industries. Thus, modifications of yield and composition of this essential oil by genetic engineering should have important scientific and commercial applications. We generated transgenic spike lavender plants expressing the Arabidopsis thaliana HMG1 cDNA, encoding the catalytic domain of 3-hydroxy-3-methylglutaryl CoA reductase (HMGR1S), a key enzyme of the mevalonic acid (MVA) pathway. Transgenic T0 plants accumulated significantly more essential oil constituents as compared to controls (up to 2.1- and 1.8-fold in leaves and flowers, respectively). Enhanced expression …

ChlorophyllTransgeneArabidopsisStigmasterolLavandula latifoliaMevalonic AcidPlant ScienceMevalonic acidReductaselaw.inventionchemistry.chemical_compoundlawBotanyOils VolatileArabidopsis thalianaCarotenoidEssential oilchemistry.chemical_classificationStigmasterolbiologyPhytosterolsfood and beveragesPigments BiologicalPlants Genetically Modifiedbiology.organism_classificationCarotenoidsSitosterolsUp-RegulationPlant LeavesLavandulachemistryBiochemistryMonoterpenesHydroxymethylglutaryl CoA ReductasesSesquiterpenesAgronomy and Crop ScienceBiotechnologyPlant Biotechnology Journal
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