Search results for "Lead"
showing 10 items of 1360 documents
Narrativa dei Caraibi nel nuovo millennio
2020
L’etichetta “Letterature franco-caraibica” utilizzata, per convenzione, dalla critica per indicare unitariamente la produzione letteraria in lingua francese della regione centrale del Continente americano è assai impropria. La regione dei Caraibi abbraccia, infatti, sia alcune delle isole dell’arcipelago delle Piccole Antille (Martinica, Guadalupa), sia l’isola di Haïti, che fa parte delle Grandi Antille, che la Guiana incastonata sulla costa orientale dell’America meridionale. Pur nella diversità dei movimenti ideologici e degli avvenimenti storici che si sono succeduti nella regione, le opere letterarie degli scrittori caraibici francofoni, nel loro insieme, hanno oscillato, e continuano …
Caraibi: un "archipel inachevé"
2018
L’etichetta “Letterature franco-caraibica” utilizzata, per convenzione, dalla critica per indicare unitariamente la produzione letteraria in lingua francese della regione centrale del Continente americano è assai impropria. La regione dei Caraibi abbraccia, infatti, sia alcune delle isole dell’arcipelago delle Piccole Antille (Martinica, Guadalupa), sia l’isola di Haïti, che fa parte delle Grandi Antille, che la Guiana incastonata sulla costa orientale dell’America meridionale. Pur nella diversità dei movimenti ideologici e degli avvenimenti storici che si sono succeduti nella regione, le opere letterarie degli scrittori caraibici francofoni, nel loro insieme, hanno oscillato, e continuano …
A simple method for preoperative assessment of the best fitting electrode length in single lead VDD pacing.
1996
For single lead VDD pacing, electrodes with various distances between the lead tip and the floating atrial dipole (AV distance) are available. Using different AV distances allows positioning of the atrial dipole in the mid- to high right atrium, regardless of the size of the right heart. In this position, reliable atrial sensing and rejection of ventricular far-field potentials can be expected. A simple test for the preoperative assessment of the best fitting AV distance in the individual patient was tested. We studied 24 consecutive patients prior to implantation of a VDD pacemaker. With the patient in supine position, a test electrode with an AV distance of 13 cm was taped onto the thorax…
Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects.
2012
Up-regulation of the folding machinery of the heat-shock protein 90 (Hsp90) chaperone protein is crucial for cancer progression. The two Hsp90 isoforms (α and β) play different roles in response to chemotherapy. To identify isoform-selective inhibitors of Hsp90(α/β)/cochaperone p23 interactions, we developed a dual-luciferase (Renilla and Firefly) reporter system for high-throughput screening (HTS) and monitoring the efficacy of Hsp90 inhibitors in cell culture and live mice. HTS of a 30,176 small-molecule chemical library in cell culture identified a compound, N -(5-methylisoxazol-3-yl)-2-[4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-ylthio]acetamide (CP9), that binds to Hsp90(α/β) an…
Mobility determination of lead isotopes in glass for retrospective radon measurements
2008
In retrospective radon measurements, the 22-y half life of (210)Pb is used as an advantage. (210)Pb is often considered to be relatively immobile in glass after alpha recoil implanted by (222)Rn progenies. The diffusion of (210)Pb could, however, lead to uncertain wrong retrospective radon exposure estimations if (210)Pb is mobile and can escape from glass, or lost as a result of cleaning-induced surface modification. This diffusion was studied by a radiotracer technique, where (209)Pb was used as a tracer in a glass matrix for which the elemental composition is known. Using the ion guide isotope separator on-line technique, the (209)Pb atoms were implanted into the glass with an energy of …
Combination of measurements of the top-quark pair production cross section from the Tevatron Collider
2014
We combine six measurements of the inclusive top-quark pair (tt̄) production cross section (σtt̄) from data collected with the CDF and D0 detectors at the Fermilab Tevatron with proton-antiproton collisions at s=1.96TeV. The data correspond to integrated luminosities of up to 8.8fb-1. We obtain a value of σtt̄=7.60±0.41pb for a top-quark mass of mt=172.5GeV. The contributions to the uncertainty are 0.20 pb from statistical sources, 0.29 pb from systematic sources, and 0.21 pb from the uncertainty on the integrated luminosity. The result is in good agreement with the standard model expectation of 7.35-0.33+0.28pb at next-to-next-to-leading order and next-to-next-to leading logarithms in pert…
Electroweak measurements in electron-positron collisions at W-boson-pair energies at LEP
2013
The ALEPH, DELPHI, L3, OPAL collaborations and LEP Electroweak Working Group.-- arXiv:1302.3415
Leadership ethical dimension: a requirement in TQM implementation
2002
Deals with theoretical arguments that justify why the leadership of managers and its ethical dimension is a powerful enabler for TQM efforts to sustain, together with a systematic management. Starts by setting out a multidimensional conception of leadership in which the ethical sphere is explicitly considered. The principles articulating TQM are then analysed, studying the role of leadership and its ethical dimension, in their implementation. Concludes with five propositions, stating that the explicit consideration of leadership’s ethical dimension is required in order to achieve a complete, deep and sustained deployment of TQM principles. Draws implications for managers and researchers.
Conventional and transactional authenticities in small-culture tourism
2016
T-bet and mucosal Th1 responses in the gastrointestinal tract
2002
T cells play an essential role in regulating mucosal immune responses in the gastrointestinal tract. Recent observations on T helper cell differentiation and activation by regulatory transcription factors-especially T-bet-in chronic inflammatory diseases have provided new perspectives for understanding mucosal immunity. Here we summarise recent advances in the field of transcription factors and discuss the implications of these findings for future therapeutic approaches in inflammatory bowel diseases. In particular, we have focused on the role of T-bet in controlling mucosal Th1 responses in the gastrointestinal tract.