Search results for "Lectin"

ChemInform Abstract: Syntheses of Sialyl Lewis A Glycopeptides - A Partial Sequence of the P-Selectin Ligand PSGL-1.

2000

S-type lectins occur also in invertebrates: high conservation of the carbohydrate recognition domain in the lectin genes from the marine sponge Geodi…

1993

The marine sponge Geodia cydonium contains several lectins. The main component, called lectin-1, is composed of three to four identical subunits. The subunits of the lectins were cloned from a cDNA library; two clones were obtained. From the deduced aa sequence of one clone, LECT-1, a mol. wt of 15,313 Da is calculated; this value is in good agreement with mass spectrometric analysis of 15,453 +/- 25 Da. The sequence of another clone, LECT-2, was analysed and the aa sequence was deduced (15,433 Da). The two subunits have a framework sequence of 38 conserved aa which are characteristic for the carbohydrate-binding site of vertebrate S-type lectins. Clustering of lectin sequences of various s…

A Collector Deceives—About the Ways of Deceiving Women by Men and Men by Women as far as Spending Money on Collecting Items Is Concerned

2022

The presented research shows that neither women nor men are honest with their partners when informing them about the amount of money spent on collecting items. Their behaviour may show signs of addiction to collecting. Men in comparison to women spend more and are less likely to lower the amounts of money spent on collected items. Those who earn more spend more on their collections. Women and men also use different techniques of hiding their expenses. Women do not inform about their expenses using denying techniques (such as saying that it was bought/borrowed a long time ago, etc.), whereas men inform about expenses but use preventive techniques (such as exchange). What is more, men tend to…

Preservation in Disaster Situations: a case study of the Valvilla Wool Mill Museum, Finland

2013

This article discusses the role of documentation and rescue planning in minimizing collection damages in disaster situations. The topic is surveyed through a case study of a fire that occurred in 2003 at the Valvilla Wool Mill museum in Hyvinkää, in Southern Finland. This incident caused significant damage to the authenticity and integrity of the museum’s archival collection. Both the fire and the extinguishing of the fire caused severe damage to items in the archival collection. Deterioration continued during aftercare, causing serious secondary collection damage because the methods of the first aid and aftercare were spontaneously planned and applied. By using the Valvilla Wool Mill museu…

Spine and test skeletal matrices of the Mediterranean sea urchinArbacia lixula- a comparative characterization of their sugar signature

2015

15 pages; International audience; Calcified structures of sea urchins are biocomposite materials that comprise a minor fraction of organic macromolecules, such as proteins, glycoproteins and polysaccharides. These macromolecules are thought to collectively regulate mineral deposition during the process of calcification. When occluded, they modify the properties of the mineral. In the present study, the organic matrices (both soluble and insoluble in acetic acid) of spines and tests from the Mediterranean black sea urchin Arbacia lixula were extracted and characterized, in order to determine whether they exhibit similar biochemical signatures. Bulk characterizations were performed by mono-di…

Analysis of the Sponge [Porifera] Gene Repertoire: Implications for the Evolution of the Metazoan Body Plan

2003

Sponges [phylum Porifera] form the basis of the metazoan kingdom and represent the evolutionary earliest phylum still extant. Hence, as living fossils, they are the taxon closest related to the hypothetical ancestor of all Metazoa, the Urmetazoa. Until recently, it was still unclear whether sponges are provided with a defined body plan. Only after the cloning, expression and functional studies of characteristic metazoan genes, could it be demonstrated that these animals comprise the structural elements which allow the sponge cells to organize themselves according to a body plan. Adhesion molecules involved in cell—cell and cell—matrix interactions have been identified. Among the cell—cell a…

La intervención de Cenicienta en la construcción de las pirámides. Un tipo iconográfico en la primera serie litográfica de las Maravillas del mundo

2020

En el siglo XVI se realiza la primera serie de litografías de las Maravillas del mundo. En ellas se representan las arquitecturas más emblemáticas de la Antigüedad. Pero en la relativa a las pirámides de Egipto se esconde un tipo iconográfico que pasa desapercibido si no se conocen las fuentes historiográficas griegas. Alude a Rhodopis, la primera Cenicienta, y su papel clave en la construcción de las pirámides. Maarten Van Heemskerck y Philips Galle nos guían hasta los historiadores clásicos Heródoto y Estrabón a través de la iconografía, para hacernos conocedores de la historia de la joven Rhodopis, una joven griega cuyo zapato toma un águila y deja caer en el regazo del faraón egipcio. D…

Transgenic overexpression of corticotropin releasing hormone provides partial protection against neurodegeneration in an in vivo model of acute excit…

2008

Abstract Corticotropin releasing hormone (CRH) is the central modulator of the mammalian hypothalamic–pituitary–adrenal (HPA) axis. In addition, CRH affects other processes in the brain including learning, memory, and synaptic plasticity. Moreover, CRH has been shown to play a role in nerve cell survival under apoptotic conditions and to serve as an endogenous neuroprotectant in vitro . Employing mice overexpressing murine CRH in the CNS, we observed a differential response of CRH-overexpressing mice (CRH-COE hom -Nes) to acute excitotoxic stress induced by kainate compared with controls (CRH-COE con -Nes). Interestingly, CRH-overexpression reduced the duration of epileptic seizures and pre…

EVOLUTION, ADAPTATION AND IMMUNE FUNCTIONS OF FISH LECTINS

2019

Fish are equipped with a complex lectin repertoire that, like mammals, are involved almost all the immune reactions. Carbohydrate recognition and interactions mediated by lectins have been recognized involved in vertebrate innate immunity, not only for recognition of potential pathogens, but also acting in the agglutination, immobilization and other functional steps. In fish, C, F types galectins, Rhamnose-bind- ing lectin (RBL) and pentraxin have been identified in both car- tilaginous and bony fish. In addition, selectins and other genes have been found in the currently available fish genomes. On the basis of our results about F-type and RBL lectins we showed that: lectin repertoires in f…

F-type lectin from the sea bass (Dicentrarchus labrax): purification, cDNA cloning, tissue expression and localization, and opsonic activity.

2009

Recently described biochemical and structural aspects of fucose-binding lectins from the European eel (Anguilla anguilla) and striped bass (Morone saxatilis) led to the identification of a novel lectin family ("F-type" lectins) characterized by a unique sequence motif and a characteristic structural fold. The F-type fold is shared not only with other members of this lectin family, but also with apparently unrelated proteins ranging from prokaryotes to vertebrates. Here we describe the purification, biochemical and molecular properties, and the opsonic activity of an F-type lectin (DlFBL) isolated from sea bass (Dicentrarchus labrax) serum. DlFBL exhibits two tandemly arranged carbohydrate-r…