Search results for "Lee"

showing 10 items of 1847 documents

Associations between sleep deficit and academic achievement - triangulation across time and subject domains among students and teachers in TIMSS in N…

2022

Abstract Background Sufficient sleep is important to an individual’s health and well-being, but also for school achievement among adolescents. This study investigates the associations between sleepiness, sleep deficits, and school achievements among adolescents. Methods This trend study involved a representative sample of Norwegian adolescents based on the “Trends in International Mathematics and Science Study” (TIMSS), N = 4499 (2015) and N = 4685 (2019) and their teachers. The students were 9th graders from a Norwegian compulsory secondary school. The survey included questions on students’ sleepiness as students reported in 2019 and sleep deficits among students that limited teaching in c…

Academic SuccessSchoolsSleepinessAdolescentPublic Health Environmental and Occupational HealthHumansVDP::Medisinske Fag: 700SleepStudentsMathematics
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A controlled clinical study of periodontal health in anticoagulated patients : assessment of bleeding on probing

2017

Background According to the Spanish Society of Cardiology, 700,000 patients receive oral anticoagulants, and in these cases bleeding on probing (BOP) could be altered. However, no studies have analyzed the periodontal status of these patients and the effects anticoagulants may have upon BOP. A study was made of the possible relationship between plaque index, probing depth, INR (International Normalized Ratio) and acenocoumarol dose versus the clinical signs of BOP in a sample of anticoagulated patients. Likewise, an analysis was made of oral hygiene habits and attitude towards bleeding in these patients. Material and Methods A controlled observational clinical study was made in La Ribera Ho…

Acenocoumarolmedicine.medical_specialtybusiness.industryResearchBleeding on probing030206 dentistry030230 surgeryBleed:CIENCIAS MÉDICAS [UNESCO]Oral hygieneClinical study03 medical and health sciences0302 clinical medicineHomogeneousInternal medicineUNESCO::CIENCIAS MÉDICASmedicineLack of knowledgeObservational studyPeriodontologymedicine.symptombusinessGeneral Dentistrymedicine.drug
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Data from: Assessing metabolic constraints on the maximum body size of actinopterygians: locomotion energetics of Leedsichthys problematicus (Actinop…

2019

Maximum sizes attained by living actinopterygians are much smaller than those reached by chondrichthyans. Several factors, including the high metabolic requirements of bony fishes, have been proposed as possible body-size constraints but no empirical approaches exist. Remarkably, fossil evidence has rarely been considered despite some extinct actinopterygians reaching sizes comparable to those of the largest living sharks. Here, we have assessed the locomotion energetics of Leedsichthys problematicus, an extinct gigantic suspension-feeder and the largest actinopterygian ever known, shedding light on the metabolic limits of body size in actinopterygians and the possible underlying factors th…

Actinopterygiansmedicine and health careLeedsichthys problematicusmetabolic constraintsLife SciencesMedicinegigantismPachycormiformes
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Is the nonREM–REM sleep cycle reset by forced awakenings from REM sleep?

2002

In selective REM sleep deprivation (SRSD), the occurrence of stage REM is repeatedly interrupted by short awakenings. Typically, the interventions aggregate in clusters resembling the REM episodes in undisturbed sleep. This salient phenomenon can easily be explained if the nonREM–REM sleep process is continued during the periods of forced wakefulness. However, earlier studies have alternatively suggested that awakenings from sleep might rather discontinue and reset the ultradian process. Theoretically, the two explanations predict a different distribution of REM episode duration. We evaluated 117 SRSD treatment nights recorded from 14 depressive inpatients receiving low dosages of Trimipram…

Activity CyclesMaleSelective REM sleep deprivationPolysomnographyAudiologyBehavioral NeuroscienceNIGHTSleep onset REM episodeDEPRIVATIONSlow-wave sleepmedia_commonDEPRESSIVE PATIENTSmedicine.diagnostic_testDepressionmusculoskeletal neural and ocular physiologyTRIMIPRAMINEMiddle AgedAntidepressive AgentsAnesthesiaLATENCIESFemaleWakefulnessArousalPsychologyAlgorithmspsychological phenomena and processesmedicine.drugVigilance (psychology)Adultmedicine.medical_specialtyREM episodePolysomnographymedia_common.quotation_subjectRapid eye movement sleepSleep REMExperimental and Cognitive PsychologyNon-rapid eye movement sleepmental disordersmedicineHumansWakefulnessMODULATIONUltradian rhythmINTERRUPTIONARTIFICIAL NEURAL NETWORKSRECOGNITIONTrimipramineUltradian processSleep cycleSleepEYE-MOVEMENT SLEEPPhysiology & Behavior
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Sonographic biometry of liver and spleen size in childhood.

1983

In 194 healthy children of all ages, sonographic measurements of the liver and spleen were performed on standardized section planes and normal values established. These measurement values showed an approximately linear increase in the course of development and correlated best with the body length. For a rapid orientational evaluation of the liver size, sonographic nomograms of the individual measurements were developed. The spleen size was determined by volume calculation. On the basis of an index of liver size, which was calculated from the individual measurements, a diagram for simultaneous determination of liver and spleen size could be developed. These nomograms permit objective morphom…

AdolescentStatistics as TopicSpleenNormal valuesReference ValuesMedicineHumansRadiology Nuclear Medicine and imagingChildLiver sizeUltrasonographyAnthropometrybusiness.industryUltrasoundInfant NewbornInfantAnatomyNomogramAnthropometrymedicine.anatomical_structureLiverReference valuesChild PreschoolPediatrics Perinatology and Child HealthUltrasonographybusinessSpleenPediatric radiology
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Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells

2009

AbstractTo study B-cell development from bone marrow (BM), we generated recombination-activating gene 1 (Rag1)–targeted mice lacking mature lymphocytes. B-cell development can be induced in such mice by B cell–specific restoration of a functional Rag1 transcription unit. Follicular and marginal zone B cells populated the spleen when Rag1 expression was permitted. Notably, the peritoneal cavity was dominated by bona fide B-1a cells, as judged by surface markers and functional properties. These BM-derived B-1a cells exhibited a polyclonal VDJ repertoire with substantial N nucleotide insertions. Nevertheless, physiologic frequencies of phosphatidylcholine-specific B cells were detected. Import…

Adoptive cell transfer1303 BiochemistryGenes RAG-1Immunology2720 HematologyB-Lymphocyte SubsetsSpleenBone Marrow CellsEnzyme-Linked Immunosorbent AssayMice Transgenic610 Medicine & healthBiology10263 Institute of Experimental ImmunologyBiochemistryPolymerase Chain ReactionRecombination-activating gene1307 Cell BiologyPeritoneal cavityMicemedicineAnimalsB cellB-Lymphocytes2403 ImmunologyStem CellsCell DifferentiationCell BiologyHematologyMarginal zoneFlow CytometryMolecular biologyAdoptive Transfermedicine.anatomical_structureImmunoglobulin MImmunologybiology.protein570 Life sciences; biologyBone marrow
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Interleukin-7 or Interleukin-15 Enhances Survival ofMycobacterium tuberculosis-Infected Mice

2000

ABSTRACTBoth antigen-presenting cells and immune effector cells are required to effectively eradicate or containMycobacterium tuberculosis-infected cells. A variety of cytokines are involved to ensure productive “cross talk” between macrophages and T lymphocytes. For instance, infection of macrophages with mycobacteria leads to effective interleukin-7 (IL-7) and IL-15 secretion, and both cytokines are able to maintain strong cellular immune responses of α/β and γ/δ T cells. Here we show that either cytokine is able to enhance survival ofM. tuberculosis-infected BALB/c mice significantly compared to application of IL-2, IL-4, or phosphate-buffered saline (as a control). Enhanced survival cou…

Adoptive cell transfermedicine.medical_treatmentImmunologySpleenBiologyMicrobiologyMiceImmune systemmedicineAnimalsTuberculosisInterleukin-15Mice Inbred BALB CInterleukin-7InterleukinMycobacterium tuberculosisT lymphocyteAdoptive TransferDisease Models AnimalInfectious Diseasesmedicine.anatomical_structureCytokineInterleukin 15Microbial Immunity and VaccinesImmunologyCytokinesFemaleParasitologyTumor necrosis factor alphaSpleenInfection and Immunity
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Sexual disorders and dyspnoea among women with obstructive sleep apnea

2020

Abstract Purpose We aimed to assess sexual function, sexual distress and the prevalence of female sexual dysfunction (FSD) among women with obstructive sleep apnea syndrome (OSA), and to assess if the presence of OSA and dyspnea influences the prevalence of FSD, body image during sexual activity and sexual function. Methods We assessed 23 women with new OSA diagnosis and 23 healthy age and body mass index (BMI) matched controls. Sexual functions were evaluated by Changes in Sexual Functioning Questionnaire (CSFQ), sexual dysfunction was diagnosed based on DSM-5 criteria during the semi-structured sexual interview, whereas body image was evaluated by Body Exposure during Sexual Activities Qu…

AdultAdolescentVisual analogue scaleFemale sexual dysfunctionSeverity of Illness IndexBody Mass IndexOSA03 medical and health sciencesYoung Adult0302 clinical medicineRisk FactorsSurveys and QuestionnairesPrevalenceMedicineHumans030212 general & internal medicineAgedSleep Apnea Obstructivebusiness.industrySexual functioningsexual function determinantsGeneral MedicineMiddle Ageddyspneamedicine.diseasePrognosisObstructive sleep apneaDistressSexual Dysfunction PhysiologicalSexual dysfunction030220 oncology & carcinogenesisCase-Control StudiesFemalePolandmedicine.symptombusinessSexual functionBody mass indexClinical psychologyFollow-Up StudiesAdvances in Medical Sciences
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Management of Patients With Nonvariceal Upper Gastrointestinal Bleeding

2011

*Division of Gastroenterology, and Division of Clinical Epidemiology, McGill University and the McGill University Health Centre, Montreal, Quebec, Canada; INSERM IC-P 803, CHU du Bocage, Dijon, France; Universite de Bourgogne, Dijon, France; **Department of Medicine, Division of Gastroenterology, Farncombe Family igestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada; Guelph General Hospital, Guelph and McMaster University, Guelph, Ontario, Division of Gastroenterology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; Division of Gastroenterology, Medical University Canada; f South Carlolina, Charleston, South Carolina; and the Departmen…

AdultAged 80 and overMaleSouth carolinamedicine.medical_specialtyHepatologybusiness.industryGastroenterologyClinical epidemiologyMiddle Agedmedicine.diseaseHealth centreSurgeryFamily medicinemedicineHumansFemaleUpper gastrointestinal bleedingGeneral hospitalGastrointestinal HemorrhagebusinessAgedClinical Gastroenterology and Hepatology
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A combined treatment regimen for chronic desquamative gingivitis in patients with oral lichen planus

2007

Background: Chronic desquamative gingivitis (DG) is a condition characterized by erythema, ulceration, and desquamation of the free and attached gingiva, usually expression of a district-systemic disease, such as oral lichen planus (OLP). Methods: A combined protocol of oral hygiene and topic corticosteroid therapy was applied in 30 patients with DG associated with OLP. Plaque index (PI) and bleeding on probing (BoP) were evaluated at baseline and after 3 months. Results: PI scoring was significantly lower after treatment in anterior, posterior, and all sites (P < 0.0001) as well as in vestibular and lingual ones (P < 0.0001 and P = 0.0001, respectively). BoP measures were found to be reduc…

AdultAged 80 and overMalechronic desquamative gingivitiDental Plaque IndexMiddle AgedCombined Modality TherapyStatistics NonparametricGingivitis Necrotizing Ulcerativeoral lichen planusAdrenal Cortex Hormonesbleeding gingival statuDental ScalingHumansFemaleSingle-Blind MethodPeriodontal Indexdental plaque controlAgedLichen Planus Oral
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