Search results for "Lee"

Granger causality analysis of sleep brain-heart interactions

2014

We studied the networks of Granger causality (GC) between the time series of cardiac vagal autonomic activity and brain wave activities, measured respectively as the normalized high frequency (HF) component of heart rate variability and EEG power in the δ, θ, α, σ, β bands, computed in 10 healthy subjects during sleep. GC analysis was performed by vector autoregressive modeling, and significance of each link in the network was assessed using F-statistics. The whole-night analysis revealed the existence of a fully connected network of brain-heart and brain-brain interactions, with the ß EEG power acting as a hub which conveys the largest number of GC links between the heart and brain n…

Evaluation of different transvaginal sonographic diagnostic parameters in women with postmenopausal bleeding

1998

Objective To determine whether the accuracy of transvaginal sonography to detect endometrial pathology is enhanced by assessing endometrial morphology and the regularity of the endometrial border in addition to measurement of endometrial thickness in women with postmenopausal bleeding. Design and methods A total of 159 women with post-menopausal bleeding were included in a prospective study performed at the Clinic of Obstetrics and Gynecology, University of Mainz. The results obtained on transvaginal sonographic assessment of the endometrium were compared with the histological evaluation of the operative endometrial specimen. Results A cut-off level for endometrial thickness of 5 mm had a s…

Zur therapie der �sophagusvarizenblutung in der Bundesrepublik Deutschland (West) ? Ergebnisse einer Urnfrage

1991

An 1076 chirurgischen und internistischen Abteilung in der BRD (West) wurde eine Umfrage zur Behandlung der Osophagusvarizenblutung durchgefuhrt. Es uberwiegt die Akutsklerosierung bzw. die Ballonsondenbehandlung mit nachfolgender Sklerosierung bei der aktiven Blutung. Die abdominelle Sperroperation wird bei der konservativ nicht stillbaren Blutung noch vor dem portokavalen Notshunt bevorzugt. Betablocker werden vor allem in internistischen Abteilungen zur Rezidivprophylaxe eingesetzt. Erst nach mehrfacher Rezidivblutung trotz Sklerosierung sehen etwa die Halfte der Abteilungen eine Indikation zum elektiven Shunt. Der distale splenorenale Shunt nach Warren and die portokavale Anastomose dom…

Adolescent use of social media and associations with sleep patterns across 18 European and North American countries

2023

Objective Over the past decade, concurrent with increasing social media use (SMU), there has been a shift toward poorer sleep among adolescents in many countries. The purpose of this study was to examine the cross-national associations between adolescent SMU and sleep patterns, by comparing 4 different categories of SMU (nonactive, active, intense, and problematic use). Design, setting, and participants Data were from 86,542 adolescents in 18 European and North American countries that participated in the 2017/18 Health Behaviour in School-aged study. Measurements Mixed-effects linear regression models were used to examine cross-national associations between 4 SMU categories and adolescent s…

“TRAVERSA FERROVIARIA HP-BB” (HIGH PERFORMANCE BI-BLOCK SLEEPER)”

2011

LA PREVENZIONE ED IL TRATTAMENTO DELLE PATOLOGIE HPV-CORRELATE: FOLLOW-UP E PERFORMANCE RIPRODUTTIVA

2007

Relationship between HPV-infection and reproductive performance includes patients who during trial become pregnant. Main chapter indeed represents genital lesions treatments sequelae. Clinical phase 3 studies showed that spontaneous abortion rate in both groups (Gardasil and placebo respectively) was comparable (33% vs 31.6%). Moreover, there were 25 cases of congenital abnormalities among newborns and live foetuses, and congenital abnormalities global rate was similar than normal population. Therefore, there is no evidence that Gardasil adversely influences fertility, pregnancy and neonatal outcome. Cold-cut conization, laser-conization, laser-ablation, LEEP or LLETZ are conservative techn…

Non-Thermal Ultrasonic Extraction of Polyphenolic Compounds from Red Wine Lees

2020

This study presents the results of conventional aqueous (CE) and non-conventional ultrasound-assisted (UAE) extractions of polyphenolic compounds from lees extracts of red wine varieties (Merlot and Vranac). The effect of ultrasound extraction time (t, s), and amplitude (A,%) from a 400 W ultrasound processor with different ultrasonic probes diameters (Ds, mm) on the amount and profile of polyphenolic compounds in the obtained extracts was investigated and compared to CE. The optimal conditions resulting in maximum extraction of phenolic compounds were: Probe diameter of 22 mm, amplitude 90% and extraction time for Vranac wine lees 1500 s and for Merlot wine lees extraction time of 1361 s. …

Neuroplasticity and environment: A pharmacotherapeutic approach toward preclinical and clinical understanding

2021

International audience; Emerging research in the field of behavioral neuroscience has demonstrated the fundamental role of the cerebral organization. For brain development, various important functions are required for instance synaptic plasticity and neurogenesis. This property is described in terms of neuroplasticity. Neuroplasticity denotes the extraordinary ability of the brain for the recognition of its structure and function after an experience with some external stimuli and involves in the various behavioral processes of the brain such as cognitive functions. It has multiple factors that can range from gene alteration to environmental factors. Environmental factors exert both negative…

Do different models induce changes in mortality indicators? That is a key question for extending the Lee-Carter model

2021

[EN] The parametric model introduced by Lee and Carter in 1992 for modeling mortality rates in the USA was a seminal development in forecasting life expectancies and has been widely used since then. Different extensions of this model, using different hypotheses about the data, constraints on the parameters, and appropriate methods have led to improvements in the model's fit to historical data and the model's forecasting of the future. This paper's main objective is to evaluate if differences between models are reflected in different mortality indicators' forecasts. To this end, nine sets of indicator predictions were generated by crossing three models and three block-bootstrap samples with …

Digestive vacuole of Plasmodium falciparum released during erythrocyte rupture dually activates complement and coagulation.

2012

Abstract Severe Plasmodium falciparum malaria evolves through the interplay among capillary sequestration of parasitized erythrocytes, deregulated inflammatory responses, and hemostasis dysfunction. After rupture, each parasitized erythrocyte releases not only infective merozoites, but also the digestive vacuole (DV), a membrane-bounded organelle containing the malaria pigment hemozoin. In the present study, we report that the intact organelle, but not isolated hemozoin, dually activates the alternative complement and the intrinsic clotting pathway. Procoagulant activity is destroyed by phospholipase C treatment, indicating a critical role of phospholipid head groups exposed at the DV surfa…