Search results for "Leonurus"

showing 4 items of 4 documents

Cytotoxicity of South-African medicinal plants towards sensitive and multidrug-resistant cancer cells

2016

Abstract Ethnopharmacological relevance Traditional medicine plays a major role for primary health care worldwide. Cancer belongs to the leading disease burden in industrialized and developing countries. Successful cancer therapy is hampered by the development of resistance towards established anticancer drugs. Aim In the present study, we investigated the cytotoxicity of 29 extracts from 26 medicinal plants of South-Africa against leukemia cell lines, most of which are used traditionally to treat cancer and related symptoms. Material and methods We have investigated the plant extracts for their cytotoxic activity towards drug-sensitive parental CCRF-CEM leukemia cells and their multidrug-r…

0301 basic medicineLeonotis leonurusCell SurvivalPlectranthusPharmacologyMagnoliopsidaSouth Africa03 medical and health sciences0302 clinical medicineCell Line TumorNeoplasmsDrug DiscoveryPlectranthus barbatusmedicineHumansMedicinal plantsMedicine African TraditionalPharmacologyLeonurusPlants MedicinalbiologyPlant ExtractsCancerbiology.organism_classificationmedicine.diseaseAntineoplastic Agents PhytogenicDrug Resistance MultipleLeukemia030104 developmental biologyDrug Resistance Neoplasm030220 oncology & carcinogenesisCancer cellJournal of Ethnopharmacology
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Suitability of a native South African shrub as pot plant

2006

Leonotis leonurus (L.) Br. Pubesc., also known as “lion’s ear” is a perennial shrub belonging to the Labiatae family and native to South Africa. The name of the genus derives from the Greek words leon (lion) and otòs (ear). The esthetic ornamental value of its bright orange inflorescence and its adaptation to a wide range of conditions have led a research to evaluate the suitability of L. leonurus as pot plant. Pot plants from one year rooted cuttings were grown in the Northern coast of Sicily; at the end of December, plants were pruned to 30 cm length and then moved to an unheated plastic greenhouse. Flowering started in April under protected cultivation and continued throughout the summer…

GeographyPot plantved/biologyAgroforestryved/biology.organism_classification_rank.speciesLeonotis leonurus Lion¿s ear ornamental plantForestrySettore AGR/04 - Orticoltura E FloricolturaHorticultureShrub
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Structure and Biological Activity of the Furan-Diterpenoids from the Genera Leonotis and Leonurus

2007

The present review, covering the literature up to 2006, reports the chemistry and the biological activities of the diterpenoids occurring in the aerial parts of species belonging to the genera Leonotis and Leonurus, family Lamiaceae.

PharmacologyFamily Lamiaceaenatural productLeonurusLeonuruNatural productbiologyOrganic Chemistrybiological activityBiological activitybiology.organism_classificationAnalytical ChemistryLabdanechemistry.chemical_compoundchemistryFuranLeonotiBotanyLabdaneLeonotisHETEROCYCLES
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Labdane Diterpenoids from Marrubium globosum ssp. libanoticum

2006

From the aerial parts of Marrubium globosum ssp. libanoticum, seven labdane diterpenoids were isolated. Three of them are new natural products [(13R)-9alpha,13alpha-epoxylabda-6beta(19),16(15)-diol dilactone (2), deacetylvitexilactone (7), marrulanic acid (8)], whereas the other four, namely, (13S)-9alpha,13alpha-epoxylabda-6beta(19),16(15)-diol dilactone (1), cyllenin A (3), 15-epi-cyllenin A (4), and marrulibanoside, are previously known compounds. The structures of 2, 7, and 8 were determined by spectroscopic and chemical methods.

StereochemistryLEONURUSPharmaceutical SciencePharmacognosyAnalytical ChemistryLabdanechemistry.chemical_compoundDrug DiscoveryBotanyLebanonNuclear Magnetic Resonance BiomolecularPharmacologychemistry.chemical_classificationFolk medicinePlants MedicinalMolecular StructurebiologyOrganic Chemistrybiology.organism_classificationTerpenoidComplementary and alternative medicinechemistryMolecular MedicineDiterpenesDiterpeneLactoneMarrubiumMarrubiumJournal of Natural Products
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