Search results for "Lep"

showing 10 items of 3622 documents

Intronic Variant in CNTNAP2 Gene in a Boy With Remarkable Conduct Disorder, Minor Facial Features, Mild Intellectual Disability, and Seizures

2020

Introduction: Mutations in the contactin-associated protein-like 2 (CNTNAP2) gene (MIM#604569) encoding for CASPR2, a cell adhesion protein of the neurexin family, are known to be associated with autism, intellectual disability, and other neuropsychiatric disorders. A set of intronic deletions of CNTNAP2 gene has also been suggested to have a causative role in individuals with a wide phenotypic spectrum, including Pitt-Hopkins syndrome, cortical dysplasia–focal epilepsy syndrome, Tourette syndrome, language dysfunction, and abnormal behavioral manifestations. Case presentation: A 10-years-old boy was referred to the hospital with mild intellectual disability and language impairment. Moreove…

CNTNAP2conduct disorder (CD)030204 cardiovascular system & hematologyBioinformaticsPediatricsTourette syndrome03 medical and health sciencesEpilepsy0302 clinical medicine030225 pediatricsIntellectual disabilitymedicineCopy-number variationintellectual disability (ID)CNTNAP2geneintronic copy number variantbusiness.industrylcsh:RJ1-570lcsh:PediatricsBrief Research Reportmedicine.diseaseConduct disorderPediatrics Perinatology and Child HealthEpilepsy syndromesCNTNAP2 geneAutismepilepsybusiness
researchProduct

Search for anomalous production of events with two photons and additional energetic objects at CDF

2010

27 páginas, 17 figuras, 5 tablas.-- CDF Collaboration: et al.

COLLIDER DETECTORNuclear and High Energy PhysicsParticle physicsMEDIATED SUPERSYMMETRY-BREAKINGPhysics beyond the Standard ModelP(P)OVER-BAR COLLISIONSFOS: Physical sciencesElementary particleddc:500.2GAMMA PRODUCTION114 Physical sciences01 natural sciences7. Clean energyHigh Energy Physics - ExperimentMEDIATED SUPERSYMMETRY-BREAKING; CENTRAL ELECTROMAGNETIC CALORIMETER; ELECTROWEAK SYMMETRY-BREAKING; LARGE EXTRA DIMENSIONS; P(P)OVER-BAR COLLISIONS; COLLIDER DETECTOR; GAMMA PRODUCTION; ROOT-S=1.96 TEV; QCD; PYTHIA-5.7Nuclear physicsHigh Energy Physics - Experiment (hep-ex)13.85Rm; 13.85Qk; 18.80.-j; 14.80.Ly0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]PYTHIA-5.7010306 general physicsPhysicsMuonLuminosity (scattering theory)hep-ex010308 nuclear & particles physicsPhysicsLARGE EXTRA DIMENSIONSQCDCENTRAL ELECTROMAGNETIC CALORIMETERROOT-S=1.96 TEVLarge extra dimensionHigh Energy Physics::ExperimentELECTROWEAK SYMMETRY-BREAKINGCollider Detector at FermilabEvent (particle physics)Lepton
researchProduct

Measurement of the lifetime of tau-lepton

1996

The tau lepton lifetime is measured with the L3 detector at LEP using the complete data taken at centre-of-mass energies around the Z pole resulting in tau_tau = 293.2 +/- 2.0 (stat) +/- 1.5 (syst) fs. The comparison of this result with the muon lifetime supports lepton universality of the weak charged current at the level of six per mille. Assuming lepton universality, the value of the strong coupling constant, alpha_s is found to be alpha_s(m_tau^2) = 0.319 +/- 0.015(exp.) +/- 0.014 (theory). The tau lepton lifetime is measured with the L3 detector at LEP using the complete data taken at centre-of-mass energies around the Z pole resulting in τ τ =293.2 ± 2.0 (stat) ± 1.5 (syst) fs . The c…

COLLISIONSNuclear and High Energy PhysicsParticle physicsLUND MONTE-CARLOPAIR PRODUCTIONElectron–positron annihilationFOS: Physical sciencesElementary particleddc:500.201 natural sciences7. Clean energyResonance (particle physics)JET FRAGMENTATIONDECAYSHigh Energy Physics - ExperimentNuclear physicsParticle decayHigh Energy Physics - Experiment (hep-ex)0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]SILICON MICROVERTEX DETECTORPRECISE MEASUREMENTLimit (mathematics)QCD ANALYSIS010306 general physicsL3 EXPERIMENTCoupling constantPhysicsMuonAnnihilationTEST BEAME+E-PHYSICS010308 nuclear & particles physicsALPHA(S)High Energy Physics::PhenomenologyDetectorPair productionSPECTRAL FUNCTIONSComputingMethodologies_DOCUMENTANDTEXTPROCESSINGHigh Energy Physics::ExperimentParticle Physics - ExperimentLeptonNuclear and Particle Physics Proceedings
researchProduct

Search for neutral heavy leptons produced in Z decays

1997

Weak isosinglet Neutral Heavy Leptons ($\nu_m$) have been searched for using data collected by the DELPHI detector corresponding to $3.3\times 10^{6}$ hadronic~Z$^{0}$ decays at LEP1. Four separate searches have been performed, for short-lived $\nu_m$ production giving monojet or acollinear jet topologies, and for long-lived $\nu_m$ giving detectable secondary vertices or calorimeter clusters. No indication of the existence of these particles has been found, leading to an upper limit for the branching ratio $BR($Z$^0\rightarrow \nu_m \overline{\nu})$ of about $1.3\times10^{-6}$ at 95\% confidence level for $\nu_m$ masses between 3.5 and 50 GeV/$c^2$. Outside this range the limit weakens rap…

COLLISIONSParticle physicsE+E ANNIHILATIONPhysics and Astronomy (miscellaneous)Electron–positron annihilationHadronMASSJet (particle physics)HIGH-ENERGY-PHYSICS; MONOJET PRODUCTION; E+E ANNIHILATION; MONTE-CARLO; BOSON; LIMITS; MASS; LEP; PERFORMANCE; COLLISIONSHIGH-ENERGY-PHYSICS01 natural sciences7. Clean energyMONOJET PRODUCTIONNuclear physicsLIMITSMONTE-CARLO0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]010306 general physicsDELPHIBosonPhysics010308 nuclear & particles physicsBranching fractionHigh Energy Physics::PhenomenologyBOSONLEPPERFORMANCELARGE ELECTRON POSITRON COLLIDERPARTICLE PHYSICS; LARGE ELECTRON POSITRON COLLIDER; DELPHILarge Electron–Positron ColliderPARTICLE PHYSICSHigh Energy Physics::ExperimentNeutrinoParticle Physics - ExperimentLepton
researchProduct

Abelian realization of phenomenological two-zero neutrino textures

2014

In an attempt at explaining the observed neutrino mass-squared differences and leptonic mixing, lepton mass matrices with zero textures have been widely studied. In the weak basis where the charged lepton mass matrix is diagonal, various neutrino mass matrices with two zeros have been shown to be consistent with the current experimental data. Using the canonical and Smith normal form methods, we construct the minimal Abelian symmetry realizations of these phenomenological two-zero neutrino textures. The implementation of these symmetries in the context of the seesaw mechanism for Majorana neutrino masses is also discussed.

CP ViolationPhysicsSterile neutrinoParticle physicsNuclear and High Energy Physics010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyFOS: Physical sciences01 natural sciencesZerosHigh Energy Physics - PhenomenologyMAJORANAHigh Energy Physics - Phenomenology (hep-ph)Seesaw mechanismMass Matrix0103 physical sciencesCP violationlcsh:QC770-798High Energy Physics::Experimentlcsh:Nuclear and particle physics. Atomic energy. RadioactivityAbelian groupNeutrino010306 general physicsNeutrino oscillationLeptonNuclear Physics B
researchProduct

Oral Manifestations of Wolf-Hirschhorn Syndrome: Genotype-Phenotype Correlation Analysis

2020

Background: Wolf-Hirschhorn syndrome (WHS) is a rare disease caused by deletion in the distal moiety of the short arm of chromosome 4. The objectives of this study were to report the most representative oral findings of WHS, relate them with other clinical characteristics of the disease, and establish possible phenotype-genotype correlation. Methods: The study was conducted at 6 reference centers distributed throughout Spain during 2018&ndash

Candidate genePediatricsmedicine.medical_specialtyGenotypegenotypelcsh:MedicineOligodontiaDiseaseContiguous gene syndromeOdontologiaArticle03 medical and health sciencesEpilepsy0302 clinical medicineGenotypemedicineOral manifestationsWolf–Hirschhorn syndrome0303 health sciencesWolf-Hirschhorn syndromebusiness.industry030305 genetics & hereditylcsh:RGeneral MedicineStomatognathic diseasesmedicine.disease4p-Patologiaoral manifestationsstomatognathic diseasesbusiness030217 neurology & neurosurgeryRare diseasestomatognathic diseasesJournal of Clinical Medicine
researchProduct

Letter to the Editor Regarding the Article Whole-Exome Sequencing in NF1-Related West's Syndrome Leads to the Identification of KCNC2 as a Novel Cand…

2020

Candidate geneShaw Potassium ChannelsLetter to the editorEpilepsybusiness.industryMEDLINEWest's syndromeGeneral MedicineComputational biologymedicine.diseaseSettore MED/39 - Neuropsichiatria InfantileEpilepsyShaw Potassium ChannelsPediatrics Perinatology and Child HealthExome SequencingMedicineHumansIdentification (biology)Neurology (clinical)businessSpasms InfantileExome sequencing
researchProduct

Neurosecretion in the Frontal Ganglion of the Stick Insect, Carausius morosus

1978

The presence of neurosecretory cells in the frontal ganglion (FG) has been demonstrated only in the Lepidoptera Bombyx (BOUNHIOL et al., 1953), Manduca (BORG et al., 1973; BELL et al., 1974), and Diatraea (YIN and CHIPPENDALE, 1975). In Manduca and Diatraea the neurosecretory material of the FG is apparently involved in the regulation of diapause.

Carausius morosusDiatraeaLepidoptera genitaliabiologymedia_common.quotation_subjectInsectDiapauseManducabiology.organism_classificationNeurosecretionBombyxmedia_commonCell biology
researchProduct

Effect of genetics polymorphism of carbamazepine – metabolizing enzymes in epileptic patients

2013

Carbamazepine epilepsy
researchProduct

In vitro effect of leptin on human cardiac contractility

2019

AbstractLeptin, a hormone produced by adipose tissue, has been linked to many regulatory pathways. Its role in the complex relationship between obesity and CVD is not yet clear. The aim of the present study was to evaluate whether leptin interferes directly with cardiac function regulation, altering its contractile force character, and hence contributing to different pathological processes. Muscle samples were obtained from human atrial myocardium. Each trial included two samples from the same patient. They were simultaneously electrically stimulated under sustained perfusion to perform isometric contractions. One sample was treated with a high concentration of human recombinant leptin (1 µ…

Cardiac function curveLeptinmedicine.medical_specialtyContraction (grammar)Endocrinology Diabetes and MetabolismAdipose tissue030209 endocrinology & metabolismIsometric exercise030204 cardiovascular system & hematologyContractility03 medical and health sciences0302 clinical medicineInternal medicinemedicineObesityContraction forceNutrition and Dieteticsbusiness.industryLeptinCD contraction durationEndocrinologyCardiac contractilityCF maximal isometric contraction forcebusinessPerfusionKH Krebs–HenseleitFood ScienceHormoneResearch ArticleJournal of Nutritional Science
researchProduct