Search results for "Letter to the Editor"

showing 10 items of 155 documents

In Reply – Association of Renin Angiotensin System Blockers with Outcomes in Patients With COVID-19

2020

2019-20 coronavirus outbreakmedicine.medical_specialtyhypertensionCoronavirus disease 2019 (COVID-19)business.industrySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Renin-Angiotensin COVID-19 hypertensionCOVID-19General MedicineRenin-Angiotensin SystemBetacoronavirusInternal medicineRenin–angiotensin systemHumansMedicineIn patientCoronavirus InfectionsbusinessPandemicsRenin-AngiotensinLetter to the EditorMayo Clinic Proceedings
researchProduct

CD1a-positive infiltrating-dendritic cell density and 5-year survival from human breast cancer.

2003

Infiltrating CD1a(+) dendritic cells (DCs) have been associated with increased survival in a number of human cancers. This study investigated DC infiltration within breast cancers and the association with survival. Classical established prognostic factors, of tumour size, lymph node status, histological grade, lympho-vascular invasion, the KI-67 (MIB-1) fraction and the Nottingham Prognostic Index (NPI) were also compared. A total of 48 breast cancer patients were followed from the time of surgery and CD1a density analysis for 5 years or until death. Our data set validated previous studies, which show a relationship between survival and the NPI (P0.001), tumour size (P0.01) and lymph node s…

AdultCancer ResearchCellular immunityPathologymedicine.medical_specialtyMammary glandBreast NeoplasmsCD1asurvivalAntigens CD1Breast cancerbreast cancerPredictive Value of Testsmental disordersmedicineHumansskin and connective tissue diseasesAntigen-presenting cellLetter to the EditorSurvival analysisAgedAged 80 and overintegumentary systembusiness.industryMolecular and Cellular PathologyCancerDendritic cellDendritic CellsDuctal carcinomaMiddle Agedmedicine.diseasePrognosisSurvival Analysismedicine.anatomical_structureOncologyCancer researchFemalebusinessBritish journal of cancer
researchProduct

Addressing the impact of SARS-CoV-2 infection in persons with congenital bleeding disorders: The Italian MECCOVID-19 study

2021

congenital bleeding disorders

AdultInheritedMalePediatricsmedicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)congenital bleeding disorderscongenital bleeding disorderSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)haemophiliaHemorrhageHaemophiliaLetter to the EditorsSARS‐CoV‐2Young AdultBlood Coagulation Disorders InheritedCOVID‐19congenital bleeding disorders; COVID-19; epidemiology; haemophilia; observational study; SARS-CoV-2; Adult; Aged; Blood Coagulation Disorders Inherited; COVID-19; Child Preschool; Disease Management; Female; Hemorrhage; Humans; Italy; Male; Middle Aged; SARS-CoV-2; Young AdultEpidemiologymedicineHumansYoung adultDisease management (health)ChildPreschoolLetter to the EditorGenetics (clinical)Agedbusiness.industrySARS-CoV-2COVID-19Disease ManagementHematologyGeneral MedicineBlood Coagulation DisordersMiddle Agedmedicine.diseaseItalySARS-CoV-2.Child PreschoolObservational studyepidemiologyobservational studyFemalebusiness
researchProduct

Rickettsia typhi and Haemophagocytic Syndrome

2017

Appropriate therapy (dexamethasone, cyclosporin, and etoposide) could save the patient in those cases in which the pathogen-direct therapy has not been sufficient by itself to control the disease.

AdultMaleFeverVomiting030231 tropical medicineTime-to-Treatment03 medical and health sciences0302 clinical medicineFatal OutcomeVirologyRickettsia typhiMedicineAnimalsHumansTreatment FailureRickettsia prowazekiiRickettsia typhileishmaniasisLetter to the EditorTransaminasesAgedAged 80 and overbiologybusiness.industryNauseaTyphus Endemic Flea-BorneExanthemaMiddle Agedbiology.organism_classificationVirologyTexasThrombocytopeniaAnti-Bacterial AgentsInfectious Diseases030211 gastroenterology & hepatologyParasitologyFemalebusinessTyphus Epidemic Louse-BorneThe American Journal of Tropical Medicine and Hygiene
researchProduct

Updating semen analysis: a subpopulation approach

2019

AdultMaleInfertilityMultivariate analysisUrologyDNA FragmentationSemen analysisBiologylcsh:RC870-923Andrology03 medical and health sciences0302 clinical medicinemedicineHumansLetter to the EditorInfertility MaleSperm motilityPrincipal Component Analysis030219 obstetrics & reproductive medicineSperm Countmedicine.diagnostic_test0402 animal and dairy science04 agricultural and veterinary sciencesGeneral MedicineHydrogen-Ion ConcentrationMiddle Agedmedicine.diseaselcsh:Diseases of the genitourinary system. UrologySpermatozoa040201 dairy & animal scienceChromatinChromatinSemen AnalysisMultivariate AnalysisPrincipal component analysisSperm MotilityDNA fragmentationAsian Journal of Andrology
researchProduct

Predictive factors of immune tolerance treatment response in severe haemophilia A patients with inhibitors: A real‐world report from a single centre,…

2019

AdultMalePediatricsmedicine.medical_specialtyTreatment responseOnline LettersMEDLINEHemophilia AImmune toleranceHumansMedicineProspective StudiesTreatment FailureChildLetters to the EditorProspective cohort studyLetter to the EditorGenetics (clinical)Retrospective StudiesFactor VIIIbusiness.industryRetrospective cohort studyHematologyGeneral MedicineSingle centreLong term learningFemaleSevere haemophilia AbusinessHaemophilia
researchProduct

Artificial Versus Video-Based Immersive Virtual Surroundings: Analysis of Performance and User's Preference.

2018

Introduction. Immersive virtual reality (VR) laparoscopy simulation connects VR simulation with head-mounted displays to increase presence during VR training. The goal of the present study was the comparison of 2 different surroundings according to performance and users’ preference. Methods. With a custom immersive virtual reality laparoscopy simulator, an artificially created VR operating room (AVR) and a highly immersive VR operating room (IVR) were compared. Participants (n = 30) performed 3 tasks (peg transfer, fine dissection, and cholecystectomy) in AVR and IVR in a crossover study design. Results. No overall difference in virtual laparoscopic performance was obtained when comparing …

AdultMaleSurgeonsEducation Medicalbusiness.industryVirtual RealityMiddle Aged03 medical and health sciencesYoung Adult0302 clinical medicine030220 oncology & carcinogenesisSurveys and QuestionnairesLaparoscopic simulatorImmersion (virtual reality)MedicineHumans030211 gastroenterology & hepatologySurgeryFemaleLaparoscopyClinical CompetencebusinessVideo basedLetter to the EditorSimulationSurgical innovation
researchProduct

Telemedicine allows quantitative measuring of olfactory dysfunction in COVID‐19

2020

AdultMaleTelemedicine2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)SARS-CoV-2business.industrySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ImmunologyCOVID-19VirologyTelemedicineOlfaction DisordersHumansMedicineImmunology and AllergyFemaleLetters to the EditorbusinessLetter to the EditorAllergy
researchProduct

Value of whole-body magnetic resonance imaging for screening multifocal osteonecrosis in patients with polymyositis/dermatomyositis

2017

To assess the value of coronal short-tau inversion recovery whole-body MRI (STIR-WBMRI) for screening osteonecrosis in patients with polymyositis (PM)/dermatomyositis (DM).The imaging and medical records of 129 patients with PM/DM who met the Bohan and Peter diagnostic criteria were retrospectively analyzed. STIR-WBMRI was performed in all patients. 18 patients had follow-up STIR-WBMRI. 12 patients underwent regional knee and/or hip MRI while 25 patients underwent radiography of the lower extremities.STIR-WBMRI detected osteonecrosis in 15 (11.6%) patients. 38 joints were affected (mean, 2.5 per patient; range, 1-5 joints). Of the 38 joints affected by osteonecrosis, 33 had no clinical symp…

AdultMalemedicine.medical_specialtyAdolescentRadiographyWhole body imagingPolymyositisDermatomyositis030218 nuclear medicine & medical imaging03 medical and health sciencesYoung Adult0302 clinical medicinemedicineHumansRadiology Nuclear Medicine and imagingWhole Body ImagingChildLetter to the EditorAgedRetrospective Studies030203 arthritis & rheumatologyAged 80 and overmedicine.diagnostic_testFull Paperbusiness.industryMedical recordOsteonecrosisRetrospective cohort studyMagnetic resonance imagingGeneral MedicineDermatomyositisMiddle Agedmedicine.diseaseMagnetic Resonance ImagingSurgeryEarly DiagnosisCoronal planeFemaleRadiologybusiness
researchProduct

Amplification of human β-glucoronidase gene for appraising the accuracy of negative SARS-CoV-2 RT-PCR results in upper respiratory tract specimens

2020

Real-time reverse transcription polymerase-chain reaction (RT-PCR) is the mainstay of Covid-19 diagnosis. False-negative RT-PCR results may hamper clinical management of patients and hinder the adoption of epidemiological measures to control the pandemic. The current study was aimed at assessing whether amplification of β-glucoronidase (GUSB) gene would help estimate the accuracy of SARS-CoV-2 RT-PCR negative results in upper respiratory tract (URT) specimens. URT specimens that tested negative by SARS-CoV-2 RT-PCR displayed higher GUSB RT-PCR cycle thresholds (CT) (P=0.070) than those testing positive (median, 30.7; range, 27.0-40.0, and median 29.7; range 25.5-36.8, respectively), this re…

AdultMalemedicine.medical_specialtyAdolescentSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Respiratory SystemSensitivity and SpecificityGastroenterologyYoung Adult03 medical and health sciences0302 clinical medicineVirologyInternal medicinemedicineHumansIn patient030212 general & internal medicineRespiratory systemChildLetter to the EditorGeneAgedGlucuronidaseAged 80 and overReceiver operating characteristicClinical Laboratory TechniquesReverse Transcriptase Polymerase Chain ReactionSARS-CoV-2business.industryCurve analysisCOVID-19Middle AgedVirologyReverse transcriptaseGlucuronidaseTrue negativeInfectious Diseasesmedicine.anatomical_structureReal-time polymerase chain reactionChild PreschoolRNA ViralFemale030211 gastroenterology & hepatologybusinessRespiratory tract
researchProduct