Search results for "Letter to the Editor"

showing 10 items of 155 documents

Stevens-Johnson syndrome on treatment with sulfasalazine for Crohn’s disease: Need for a multidisciplinary approach

2019

Letter to editor

Adultmedicine.medical_specialtyMEDLINEMedical illustrationGastrointestinal AgentsCrohn DiseaseMultidisciplinary approachSulfasalazineGastrointestinal AgentMedical IllustrationmedicineHumansIntensive care medicinePatient Care TeamCrohn's diseasePatient care teambusiness.industryGastroenterologyStevens johnsonmedicine.diseaseLetter To The EditorSulfasalazineAdult Crohn Disease Female Gastrointestinal Agents Humans Medical Illustration Patient Care Team Stevens-Johnson Syndrome SulfasalazineStevens-Johnson SyndromeFemalebusinessHumanmedicine.drug
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Ceftolozane Pharmacokinetics in a Septic Critically Ill Patient under Different Extracorporeal Replacement Therapies

2019

Ceftolozane-tazobactam (C/T), a novel fifth-generation cephalosporin/β-lactamase inhibitor combination active against multidrug-resistant (MDR) Pseudomonas aeruginosa, is currently approved by the U.S. Food and Drug Administration (FDA) to treat complicated intra-abdominal and urinary tract

Adultmedicine.medical_specialtymedicine.drug_classCritical IllnessUrinary systemCephalosporinHemodiafiltrationMicrobial Sensitivity TestsOff-label usemedicine.disease_causeExtracorporealPharmacokineticspolycyclic compoundsmedicineHumansPseudomonas InfectionsPharmacology (medical)Intensive care medicineLetter to the EditorPharmacologyCritically illbusiness.industryPseudomonas aeruginosaPrecursor Cell Lymphoblastic Leukemia-Lymphomabacterial infections and mycosesAnti-Bacterial AgentsCephalosporinsInfectious DiseasesPseudomonas aeruginosaFemaleCeftolozanebusinessAntimicrobial Agents and Chemotherapy
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Hypertonic Stress and Amino Acid Deprivation Both Increase Expression of mRNA for Amino Acid Transport System A

2004

The activity of amino acid transport system A ([Oxender and Christensen, 1963][1]) is regulated in a variety of different ways, the best studied being the increases of its activity caused by starving cells of amino acids or by exposing them to hypertonicity (for review see [McGivan and Pastor-

Amino Acid Transport System APhysiologyCHO CellsBiologyCricetulusOsmotic PressureCricetinaeAnimalsHumansOsmotic pressureRNA MessengerAmino AcidsLetter to the Editorchemistry.chemical_classificationRegulation of gene expressionMessenger RNAChinese hamster ovary cellbiology.organism_classificationAmino acidGene Expression RegulationHypotonic SolutionschemistryBiochemistryHypertonic StressTonicityCricetulusJournal of General Physiology
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Lessons from uncertainty on antifungal treatment in ICU

2017

We read with great interest the Editorial from Moghnieh et al. on the EMPIRICUS trial and antifungal use in intensive care unit (ICU) (1). Authors described nicely the trial and some background evidence on untargeted antifungal treatment in non-neutropenic critically ill patients in ICU (2,3). However, we believe that some points may be further clarified. First, it may be useful to cite the study from Knitsch et al. among those evaluating empiric antifungal treatment in ICU (4). Knitsch et al. enrolled 252 critically ill patients with localized/generalized intra-abdominal infection either of community or of nosocomial origin requiring emergency surgery.

AntifungalPulmonary and Respiratory Medicinemedicine.medical_specialtybusiness.industryCritically illmedicine.drug_classMEDLINE030208 emergency & critical care medicinesepsis fungal infectionIntensive care unitlaw.invention03 medical and health sciences0302 clinical medicineEditorialEmergency surgerylawMedicineCommunity or030212 general & internal medicineMED/41 - ANESTESIOLOGIAbusinessIntensive care medicineLetter to the Editor
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Letter to the Editor Regarding the Article Whole-Exome Sequencing in NF1-Related West's Syndrome Leads to the Identification of KCNC2 as a Novel Cand…

2020

Candidate geneShaw Potassium ChannelsLetter to the editorEpilepsybusiness.industryMEDLINEWest's syndromeGeneral MedicineComputational biologymedicine.diseaseSettore MED/39 - Neuropsichiatria InfantileEpilepsyShaw Potassium ChannelsPediatrics Perinatology and Child HealthExome SequencingMedicineHumansIdentification (biology)Neurology (clinical)businessSpasms InfantileExome sequencing
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LETTER TO THE EDITOR. CUNICULUS 'RABBIT' - A CELTIC ETYMOLOGY

2010

Celtic languagesLetter to the editorPhilosophyEtymologyAnimal Science and ZoologyRabbit (nuclear engineering)Ancient historyWorld Rabbit Science
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Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen

2019

BACKGROUND: Although diabetic kidney disease demonstrates both familial clustering and single nucleotide polymorphism heritability, the specific genetic factors influencing risk remain largely unknown.METHODS: To identify genetic variants predisposing to diabetic kidney disease, we performed genome-wide association study (GWAS) analyses. Through collaboration with the Diabetes Nephropathy Collaborative Research Initiative, we assembled a large collection of type 1 diabetes cohorts with harmonized diabetic kidney disease phenotypes. We used a spectrum of ten diabetic kidney disease definitions based on albuminuria and renal function.RESULTS: Our GWAS meta-analysis included association result…

Collagen Type IVMale0301 basic medicineEXPRESSIONNEPHROPATHY030232 urology & nephrologyPROTEINGenome-wide association studyRECEPTOR TYROSINE KINASESBiologySUSCEPTIBILITYBioinformaticsurologic and male genital diseasesAutoantigensNephropathyEnd stage renal diseaseCohort StudiesDiabetic nephropathy03 medical and health sciences0302 clinical medicineSDG 3 - Good Health and Well-beingDiabetes mellitusGlomerular Basement MembranemedicineHumansDiabetic NephropathiesAlport syndromeLetter to the EditorCOMPLICATIONSNITRIC-OXIDEMUTATIONS1184 Genetics developmental biology physiologyGeneral Medicinemedicine.diseaseGENE3. Good healthDiabetes Mellitus Type 1030104 developmental biologyNephrology3121 General medicine internal medicine and other clinical medicineMutationAlbuminuria/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemale3111 Biomedicinemedicine.symptomCOLLECTIN 11 CL-11Genome-Wide Association StudyKidney disease
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Unexpected tumor reduction in metastatic colorectal cancer patients during SARS-Cov-2 infection: effect of ACE-2 expression on tumor cells or molecul…

2021

Colorectal cancerSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)medicine.medical_treatmentcolorectal cancermedicine.disease_causeMutually exclusive eventsMolecular oncologyMetastasismolecular oncologymedicinemetastasisprognostic biomarkerLetter to the EditorRC254-282business.industrySettore BIO/16 - Anatomia UmanaNeoplasms. Tumors. Oncology. Including cancer and carcinogensImmunotherapymedicine.diseaseMolecular mimicryOncologyTumor reductionCancer researchimmunotherapybusinesscolorectal cancer immunotherapy metastasis molecular oncology prognostic biomarker
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Unreliable predictions about COVID‐19 infections and hospitalizations make people worry: The case of Italy

2021

Computer modeling &ltmedicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)BioinformaticsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)media_common.quotation_subjectcomputer modeling < biostatistics & bioinformatics; epidemiology; statistical inference < biostatistics & bioinformaticsMEDLINEVirologycomputer modeling < biostatistics & bioinformaticsEpidemiologyHumansMedicineLetters to the EditorIntensive care medicineLetter to the Editormedia_commonSARS-CoV-2business.industryCommunicationBiostatistics &ampCOVID-19Computer modeling &lt; Biostatistics &amp; Bioinformaticsstatistical inference < biostatistics & bioinformaticsVirologyInfectious DiseasesItalyStatistical inference &lt; Biostatistics &amp; BioinformaticsepidemiologyWorrySettore SECS-S/01businessForecastingJournal of Medical Virology
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There is a relationship between obesity and COVID‐19 but more information is needed

2020

Abstract We read with particular interest your comments in Obesity regarding the Coronavirus‐19 (COVID‐19) epidemic (1) and a related manuscript by Simonnet et al. (2). Resolution of the specific relationship between obesity and COVID‐19, two existing public health epidemics, is critically needed to potentially prevent health systems worldwide from being overburdened. Few studies describing COVID‐19 with rates of obesity exist, and most are based on heterogeneous populations (Table 1) (2‐7). In cohort studies with COVID‐19 disease, obesity rates are generally reported as no higher than population‐based estimates; in contrast, subgroups of critically ill patients (e.g, intensive care unit (I…

Critical CareSARS-CoV-2Pneumonia ViralCOVID-19Social SupportComorbiditySeverity of Illness Indexobesity COVID-19 incidence prevalenceUnited StatesBetacoronavirusSocial IsolationRisk FactorsHumansObesitySettore MED/49 - Scienze Tecniche Dietetiche ApplicateLetters to the EditorCoronavirus InfectionsLetter to the EditorPandemicsObesity (Silver Spring, Md.)
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