Search results for "Leucocytes"

Involvement of leucocyte/endothelial cell interactions in anorexia nervosa.

2015

Background Anorexia nervosa is a common psychiatric disorder in adolescence and is related to cardiovascular complications. Our aim was to study the effect of anorexia nervosa on metabolic parameters, leucocyte–endothelium interactions, adhesion molecules and proinflammatory cytokines. Materials and Methods This multicentre, cross-sectional, case–control study employed a population of 24 anorexic female patients and 36 controls. We evaluated anthropometric and metabolic parameters, interactions between leucocytes polymorphonuclear neutrophils (PMN) and human umbilical vein endothelial cells (HUVEC), proinflammatory cytokines such as tumour necrosis factor alpha (TNF-α) and interleukin-6 (IL…

Effects of dietary vitamin D3 administration on innate immune response of sea bass (Dicentrarchus labrax)

2014

Effect of a Prebiotic Formulation on Frailty Syndrome

2016

Aging can result in major changes in the composition and metabolic activities of bacterial populations in the gastrointestinal system and result in impaired function of the immune system. We assessed the efficacy of prebiotic Darmocare Pre (R) (Bonusan Besloten Vennootschap (BV), Numansdorp, The Netherlands) to evaluate whether the regular intake of this product can improve frailty criteria, functional status and response of the immune system in elderly people affected by the frailty syndrome. The study was a placebo-controlled, randomized, double blind design in sixty older participants aged 65 and over. The prebiotic product was composed of a mixture of inulin plus fructooligosaccharides …

The Importance of the Variability of Leucocyte Zinc Transporter 8 (ZnT8) Gene Expression

2023

The variability of ZnT8 expression in leukocytes develops in patients witha geneticpredisposition to this condition and it decreases with age. Greater intercellular zinc accumulation may potentially provoke increased levels of its expression, as a support mechanism in zinc homeostasis. The occurrence of ZnT8 antibodies (ZnT8A) may result in leukocyte dysfunction, which is dependent i.a. on the level of ZnT8 expression. The same correlation can be observed in non-pancreatic tissues. ZnT8A occur in approximately 16.5% of research participants without any diabetes symptoms and the frequency of their occurrence decreases with age as well. The occurence of variability of ZnT8 expression in leuko…

Mediterranean Diet and White Blood Cell Count—A Randomized Controlled Trial

2021

We aimed to assess the effects of the antioxidant-rich Mediterranean diet (MedDiet) on white blood cell count. Our study population included participants in the PREvención con DIeta MEDiterránea study (average age 67 years old, 58% women, high cardiovascular risk). We assessed whether a MedDiet intervention enriched in extra-virgin olive oil or nuts, versus a low-fat control diet, modified the incidence of leukocytosis (&gt