Search results for "Liber"
showing 10 items of 1718 documents
Las elecciones y el fin de la democracia
2009
Nanoparticles and antigen-specific T-cell therapeutics: A comprehensive study on uptake and release
2015
Aim: T lymphocytes are used as cellular therapeutics in many disease entities including cancer. We investigated the uptake and retention of nanoparticles (NPs) by these nonphagocytic cells. Materials & methods: Uptake, release and toxicity of various polymeric NP preparations were analyzed by flow cytometry, confocal laser scanning microscopy and transmission electron microscopy. T-cell effector functions were measured using IFN-γ-ELISPOT and 51Chromium-release assays. Results: Amino-functionalized NPs were efficiently ingested by antigen-specific T cells without adversely influencing effector functions. NPs were stored in membrane-surrounded vesicles, with major proportions released e…
Migraciones y progreso
2008
¿Qué hacer con la OMC?
2003
Amorphous polyphosphate/amorphous calcium carbonate implant material with enhanced bone healing efficacy in a critical-size defect in rats
2016
In this study the effect of amorphous calcium carbonate (ACC) microparticles and amorphous calcium polyphosphate (polyP) microparticles (termed aCa-polyP-MP) on bone mineral forming cells/tissue was investigated in vitro and in vivo. The ACC particles (termed ACC-P10-MP) were prepared in the presence of Na-polyP. Only the combinations of polyP and ACC microparticles enhanced the proliferation rate of human mesenchymal stem cells (MSCs). Gene expression studies revealed that ACC causes an upregulation of the expression of the cell membrane-associated carbonic anhydrase IX (CA IX; formation of ACC), while the transcript level of the alkaline phosphatase (ALP; liberation of orthophosphate from…
Caliber-persistent Artery: A Case Report
2019
ABSTRACT The caliber-persistent labial artery (CPLA) is a vascular anomaly in which a main branch of the artery penetrates the submucosal area of the lip without loss of caliber. It commonly presents as an elevated soft tissue mass and is often pulsatile on manual palpation. Clinical suspicion is important, given the risk of bleeding, either from slight trauma or accidentally if lack of awareness leads to excision of the lesion owing to an incorrect diagnosis. CPLA should be considered in the differential diagnosis of any lesion affecting the lip, especially to differentiate from mucocele or squamous cell carcinoma. This particular case of CPLA in the upper lip of a girl presents a both unu…
Europa en la Calle
2000
Cambiamento climatico, liberalismo, e la distinzione pubblico-privato
2020
In questo saggio si sostiene che il cambiamento climatico metta sotto pressione una distinzione che sta al cuore della teoria e della pratica liberale, quella tra il pubblico e il privato, in modi nuovi e sistematici. Molti dei comportamenti individuali che contribuiscono al cambiamento del clima – - quali usare il computer, farsi una doccia calda, guidare una macchina, riscaldare casa, prendere l’aereo, investire qui o lì, mangiare questo o quello, e fare uno o più figli – sono generalmente considerati privati. E però oggi questi comportamenti hanno conseguenze pubbliche notevolissime, per quanto indirette, che trascendono confini sia spaziali che temporali. Il saggio considera la distinzi…
Zwecksetzungen und Zielvorstellungen in den Wirtschafts- und Soziallehren des 18. und 19. Jahrhunderts
1982
The essay examines the natural law economics of the eighteenth century and the evolutionist economics of the nineteenth century by focusing on their methods for achieving a common, nebulously articulated goal: individual fulfillment and the happiness and welfare of mankind in a free, harmoniously ordered society. Illustrating the theoretical and, in practice, effective theories derived from natural law are cammeralism, the economic philosophy of the Physiocrats, and economic liberalism. It is emphasized that these theories do not represent a linear sequence of ideas in which one set of ideas „triumphed” over a preceding one. They show instead three different consequences reflecting the inte…