Search results for "Lici"
showing 10 items of 2919 documents
Biología de Mosquitos (Diptera: Culicidae) en enclaves representativos de la Comunidad Valenciana
2014
Los mosquitos (Diptera, Culicidae) es uno de los grupos de insectos de mayor notoriedad en Salud Pública no sólo por su molesta picadura sino, sobre todo, por la gran variedad y cantidad de enfermedades que transmiten al ser humano y a los animales. Entre ellas hay que destacar la Malaria, el Dengue, la Fiebre amarilla, el Virus del Oeste del Nilo, el Chikungunya, las Filariasis y diversas Encefalitis que anualmente afectan a millones de personas en todo el mundo. Para el control de las poblaciones de mosquitos se ha de conocer bien la distribución, la biología y la etología de las especies perjudiciales. Sólo de ese modo se pueden diseñar planes de acción dirigidos específicamente al contr…
Aportaciones al conocimiento de los mosquitos (Diptera, Culicidae) de alta montaña presentes en la Península Ibérica
2009
Several larval samplings of mosquitoes (Diptera, Culicidae) in different mountainous regions of the peninsular Spain were carried out. A total of 2796 specimens belonging to 18 species were collected, nevertheless the 72.5 % of these finds includes only three of them (Cx. hortensis hortensis, Cx. pipiens and Cs. longiareolata). The adaptation capacity to a varied typology of water bodies together with the marked multivoltinism that characterizes their biotic cycles are postulated as two of the principal reasons that explain their abundances. The altitudinal distribution as well as some information about the bioecology of all the species captured are also exposed.
L2 motivation in focus : the case of Finnish comprehensive school students
2017
The aim of this study is to explore whether latent classes, i.e. subgroups of students, representing specific motivational profiles can be found among learners of different foreign languages (L2s) ...
New Challenges to Motivate Remedial EFL Students to Read Extensively
2012
Although one of the keys to improving language ability lies in the continuous and prolonged exposure to the target language, providing learners with the opportunities in the EFL environment is not easy. For Japanese learners of English, in fact, the amount of input of English is severely limited. Additionally, it is hard for them to keep motivating themselves to study English as the use of the language is often not requisite in the society. This paper explains that extensive reading (ER) is an effective method for learners with low proficiency and poor motivation to learn English, provided that Start with Simple Stories (SSS) and Sustained Silent Reading (SSR) methods are guaranteed (Takase…
Quasi-Homogeneous Linear Systems on with Base Points of Multiplicity multiplicity 5
2003
In this paper we consider linear systems of ℙ2 with all but one of the base points of multiplicity 5. We give an explicit way to evaluate the dimensions of such systems
Multiplicity and transverse momentum evolution of charge-dependent correlations in pp, p–Pb, and Pb–Pb collisions at the LHC
2016
We report on two-particle charge-dependent correlations in pp, p–Pb, and Pb–Pb collisions as a function of the pseudorapidity and azimuthal angle difference, η and ϕ respectively. These correlations are studied using the balance function that probes the charge creation time and the development of collectivity in the produced system. The dependence of the balance function on the event multiplicity as well as on the trigger and associated particle transverse momentum (pT) in pp, p–Pb, and Pb–Pb collisions at √sNN = 7, 5.02, and 2.76 TeV, respectively, are presented. In the low transverse momentum region, for 0.2 < pT < 2.0 GeV/c, the balance function becomes narrower in both η and ϕ direction…
‘Health in All Policies’ and the Urge for Coordination: The Work of Public Health Coordinators and Their Impact and Influence in Local Public Health …
2022
Building heavily on the Health in All Policies (HiAP) approach, Norway implemented the Public Health Act in 2012 to reduce social inequalities in health. Local public health coordinators (PHCs) at municipal levels were seen as tools to provide local intersectoral public health work. In this study, we examine factors related to intersectoral agency and if intersectoral work is understood as relevant to securing social justice in local policy outcomes. A national web-based survey in 2019 of all Norwegian PHCs (n = 428) was conducted with a response rate of 60%. Data were analysed through multiple linear regression, hierarchical regression modelling and structural equation modelling. Neither f…
Descubrimiento y caracterización de la estefenantrina como fármaco para la Distrofia Miotónica Tipo 1
2015
La Distrofia Miotónica tipo 1 (DM1) es una enfermedad autosómica dominante cuyos principales síntomas incluyen miotonía (incapacidad para relajar el músculo tras una contracción voluntaria), degeneración muscular, cataratas, diabetes, arritmias cardiacas y déficit cognitivo entre otros. La causa genética de la enfermedad radica en la expansión del trinucleótido CTG en el extremo 3’ no traducido del gen proteina kinasa de la distrofia miotónica (DMPK). La expansión de este trinucleótido provoca la ganancia de función tóxica del RNA al transcribirse la región expandida. El RNA portador de las expansiones tóxicas de CTG se pliega sobre sí mismo formando una horquilla de doble cadena que queda …
Expanded CCUG repeat RNA expression in Drosophila heart and muscle trigger Myotonic Dystrophy type 1-like phenotypes and activate autophagocytosis ge…
2016
AbstractMyotonic dystrophies (DM1–2) are neuromuscular genetic disorders caused by the pathological expansion of untranslated microsatellites. DM1 and DM2, are caused by expanded CTG repeats in the 3′UTR of the DMPK gene and CCTG repeats in the first intron of the CNBP gene, respectively. Mutant RNAs containing expanded repeats are retained in the cell nucleus, where they sequester nuclear factors and cause alterations in RNA metabolism. However, for unknown reasons, DM1 is more severe than DM2. To study the differences and similarities in the pathogenesis of DM1 and DM2, we generated model flies by expressing pure expanded CUG ([250]×) or CCUG ([1100]×) repeats, respectively, and compared …
Sense and Antisense DMPK RNA Foci Accumulate in DM1 Tissues during Development.
2015
International audience; Myotonic dystrophy type 1 (DM1) is caused by an unstable expanded CTG repeat located within the DMPK gene 3'UTR. The nature, severity and age at onset of DM1 symptoms are very variable in patients. Different forms of the disease are described, among which the congenital form (CDM) is the most severe. Molecular mechanisms of DM1 are well characterized for the adult form and involve accumulation of mutant DMPK RNA forming foci in the nucleus. These RNA foci sequester proteins from the MBNL family and deregulate CELF proteins. These proteins are involved in many cellular mechanisms such as alternative splicing, transcriptional, translational and post-translational regul…