Search results for "Lins"

"Table 6" of "First measurement of quarkonium polarization in nuclear collisions at the LHC"

2021

J/$\psi$ polarization parameters, measured for Pb--Pb collisions at $\sqrt{s_{\rm NN}}=5.02$ TeV, in the helicity and Collins-Soper reference frames in the rapidity interval $2.5

Lisätty todellisuus matkapuhelinsovelluksissa

2010

 Peura, Kimmo Tapio Lisätty todellisuus matkapuhelinsovelluksissa Jyväskylä: Jyväskylän yliopisto, 2010. 30s. Kandidaatintutkielma Tässä tutkielmassa käsitellään lisättyä todellisuutta ja sen sovelluksia matkapuhelimissa. Ensin esittelen, mitä lisätty todellisuus on ja miten se liittyy virtuaalitodellisuuteen. Tämän jälkeen kerron matkapuhelimesta lisätyn todellisuuden laitealustana. Lopuksi esittelen kolme matkapuhelinsovellusta, Layarin, Sekai Cameran ja Toozlan, joissa hyödynnetään lisättyä todellisuutta. Lisätty todellisuus toteutetaan yleensä käyttämällä läpinäkyviä näyttöjä tai monitoripohjaisia näyttöjä. Läpinäkyvät näytöt ovat usein päässä kannettavia näyttöjä ja niiden avulla voi t…

Tuberkulins un tuberkulina reakcijas

1929

eNOS S-nitrosylates β-actin on Cys374 and regulates PKC-θ at the immune synapse by impairing actin binding to profilin-1.

2017

The actin cytoskeleton coordinates the organization of signaling microclusters at the immune synapse (IS); however, the mechanisms involved remain poorly understood. We show here that nitric oxide (NO) generated by endothelial nitric oxide synthase (eNOS) controls the coalescence of protein kinase C-¿ (PKC-¿) at the central supramolecular activation cluster (c-SMAC) of the IS. eNOS translocated with the Golgi to the IS and partially colocalized with F-actin around the c-SMAC. This resulted in reduced actin polymerization and centripetal retrograde flow of ß-actin and PKC-¿ from the lamellipodium-like distal (d)-SMAC, promoting PKC-¿ activation. Furthermore, eNOS-derived NO S-nitrosylated ß-…

Cis-15 intermediates of biohydrogenation in the duodenal flow of cows receiving linseed

2006

Duodenal samples from a previous experiment (Akraim et al., 2006) were reanalysed for determination of cis-15 intermediates of ruminal biohydrogenation (BH). Three dry Holstein cows fitted with a duodenal cannula received a diet with 14% (dry matter basis) raw linseed. C18 fatty acids (C18FA) represented 6.3% of dietary dry matter, and contained 57.8% of C18:3. After 18 days adaptation, on each cow, twelve samples of duodenal flow were taken over 3 days, composited, and analysed for FA composition. Cis-9,trans-11,cis-15C18:3 and trans-11,cis-15C18:2 (CLnA) were identified by GC-MS. The proportion of CLnA was low, in spite of the high C18:3 intake. The first step of C18:3 BH, isomerisation t…

2019

The insulin-like growth factor (IGF) pathway plays an important role in several brain tumor entities. However, the lack of inhibitors crossing the blood–brain barrier remains a significant obstacle for clinical translation. Here, we targeted the IGF pathway using ceritinib, an off-target inhibitor of the IGF1 receptor (IGF1R) and insulin receptor (INSR), in a pediatric patient with an unclassified brain tumor and a notch receptor 1 (NOTCH1) germline mutation. Pathway analysis of the tumor revealed activation of the sonic hedgehog (SHH), the wingless and integrated-1 (WNT), the IGF, and the Notch pathway. The proliferation of the patient tumor cells (225ZL) was inhibited by arsenic trioxide …

Characterization of small HSPs from Anemonia viridis reveals insights into molecular evolution of alpha crystallin genes among cnidarians.

2014

Gene family encoding small Heat-Shock Proteins (sHSPs containing α-crystallin domain) are found both in prokaryotic and eukaryotic organisms; however, there is limited knowledge of their evolution. In this study, two small HSP genes termed AvHSP28.6 and AvHSP27, both organized in one intron and two exons, were characterised in the Mediterranean snakelocks anemone Anemonia viridis. The release of the genome sequence of Hydra magnipapillata and Nematostella vectensis enabled a comprehensive study of the molecular evolution of α-crystallin gene family among cnidarians. Most of the H. magnipapillata sHSP genes share the same gene organization described for AvHSP28.6 and AvHSP27, differing from …

A role for Toll-like receptor mediated signals in neutrophils in the pathogenesis of the anti-phospholipid syndrome.

2012

The anti-phospholipid syndrome (APS) is characterized by recurrent thrombosis and occurrence of anti-phospholipid antibodies (aPL). aPL are necessary, but not sufficient for the clinical manifestations of APS. Growing evidence suggests a role of innate immune cells, in particular polymorphonuclear neutrophils (PMN) and Toll-like receptors (TLR) to be additionally involved. aPL activate endothelial cells and monocytes through a TLR4-dependent signalling pathway. Whether this is also relevant for PMN in a similar way is currently not known. To address this issue, we used purified PMN from healthy donors and stimulated them in the presence or absence of human monoclonal aPL and the TLR4 agonis…

Redox Proteomics of the Inflammatory Secretome Identifies a Common Set of Redoxins and Other Glutathionylated Proteins Released in Inflammation, Infl…

2015

Protein cysteines can form transient disulfides with glutathione (GSH), resulting in the production of glutathionylated proteins, and this process is regarded as a mechanism by which the redox state of the cell can regulate protein function. Most studies on redox regulation of immunity have focused on intracellular proteins. In this study we have used redox proteomics to identify those proteins released in glutathionylated form by macrophages stimulated with lipopolysaccharide (LPS) after pre-loading the cells with biotinylated GSH. Of the several proteins identified in the redox secretome, we have selected a number for validation. Proteomic analysis indicated that LPS stimulated the releas…

Permanent magnet dipole stirrer for aluminium furnaces

2018

Use of permanent magnet systems for metallurgical applications have been proposed before. We have continued development of such systems by investigation use of single magnetic dipole which is realized as permanent magnet cylinder. Magnet is magnetized orthogonal to its axis and has been mounted to the side of the liquid metal reservoir. System first was modelled using small scale experiment with galinstan melt. Velocity distributions and flow patterns in reservoir using Ultrasound Doppler Anemometer were acquired and will be presented here. Additionally, numerical model using Comsol and Cenos modelling software were developed alongside analytical, non-dimensional estimation calculations. Ex…