Search results for "Lobe"
showing 10 items of 520 documents
Nanocarriers for optimizing the balance between interfollicular permeation and follicular uptake of topically applied clobetasol to minimize adverse …
2015
The treatment of various hair disorders has become a central focus of good dermatologic patient care as it affects men and women all over the world. For many inflammatory-based scalp diseases, glucocorticoids are an essential part of treatment, even though they are known to cause systemic as well as local adverse effects when applied topically. Therefore, efficient targeting and avoidance of these side effects are of utmost importance. Optimizing the balance between drug release, interfollicular permeation, and follicular uptake may allow minimizing these adverse events and simultaneously improve drug delivery, given that one succeeds in targeting a sustained release formulation to the hair…
TECNICHE DI RICOSTRUZIONE DELLA SUPERFICIE POSTERIORE DEL PADIGLIONE AURICOLARE E DELLA MASTOIDE CON LEMBI LOCALI
2007
B a c k g ro u n d. Reconstruction of the posterior auricular surface and of the mastoid has never been given much attention and there are no techniques described. The authors describe two techniques for reconstruction of these areas after cancer excision with local flaps. M e t h o d s . 13 patients have been treated after cancer resection with an advancement flap from the posterior auricular surface and a bilobed flap from the mastoid. R e s u l t s. All flaps healed uneventfully with a satisfactory aesthetic outcome. No relevant complications have been o b s e r v e d . C o n c l u s i o n s. Reconstruction of the posterior auricular surface and of the mastoid with the techniques describ…
Molecular and Insecticidal Characterization of a Cry1I Protein Toxic to Insects of the Families Noctuidae, Tortricidae, Plutellidae, and Chrysomelidae
2006
ABSTRACT The most notable characteristic of Bacillus thuringiensis is its ability to produce insecticidal proteins. More than 300 different proteins have been described with specific activity against insect species. We report the molecular and insecticidal characterization of a novel cry gene encoding a protein of the Cry1I group with toxic activity towards insects of the families Noctuidae, Tortricidae, Plutellidae, and Chrysomelidae. PCR analysis detected a DNA sequence with an open reading frame of 2.2 kb which encodes a protein with a molecular mass of 80.9 kDa. Trypsin digestion of this protein resulted in a fragment of ca. 60 kDa, typical of activated Cry1 proteins. The deduced sequen…
Beginning Becoming: The First 1000 Days
2019
Thomas Balmes’ (Babies. Studio Canal documentaries, 2010) ‘Babies’ (Baby(ies) or Bebes) provides a glimpse into the earliest experiences of four infants from four different localities in the world. Although this movie offers no interpretation of what takes place, the discerning viewer is left in no doubt of the significance of these powerful images about infants and their ways of being, doing and knowing in the earliest phases of life. The provocations of ‘Babies’ offer a useful beginning orienting place for a book – almost 10 years later – that promises to focus on becoming in the first 1000 days across a different set of five countries – this time Australia, Finland, New Zealand, Norway a…
Moving towards inclusion: how Zanzibar succeeds in transforming its education system?
2015
Ever since the proclamation of the Salamanca Statement (1994) and the Dakar Framework for Action (2000), several countries across the globe have been improving their education systems making remark...
Electrochemical reduction and carboxylation of halobenzophenones
2002
Abstract The electrochemical reduction of a series of halogenated benzophenones XC6H4COC6H4Y (1) was studied in aprotic solvents, in the absence and presence of CO2, by cyclic voltammetry (CV) and controlled-potential electrolysis. The mechanism of electroreduction in dimethylformamide (DMF) has been investigated in some detail. Most of the compounds undergo reductive carbonhalogen bond cleavage in the time window of CV. The radical anions derived from difluorobenzophenones (X=Y=4-F; X=2-F, Y=4-F) as well as from the 3-chloro derivative are quite stable with a cleavage rate constant (kc) of the order of 10−2 s−1 or less. With 4-chloro-, 2-chloro-, 4,4′-dichloro- and 2,4′-dichorobenzophen…
Fronto-parietal homotopy in resting-state functional connectivity predicts task-switching performance
2021
Homotopic functional connectivity reflects the degree of synchrony in spontaneous activity between homologous voxels in the two hemispheres. Previous studies have associated increased brain homotopy and decreased white matter integrity with performance decrements on different cognitive tasks across the life-span. Here, we correlated functional homotopy, both at the whole-brain level and specifically in fronto-parietal network nodes, with task-switching performance in young adults. Cue-to-target intervals (CTI: 300 vs. 1200 ms) were manipulated on a trial-by-trial basis to modulate cognitive demands and strategic control. We found that mixing costs, a measure of task-set maintenance and moni…
A temperature-sensitive brain tumor suppressor mutation of Drosophila melanogaster: Developmental studies and molecular localization of the gene
1993
The recessive-lethal, temperature-sensitive (ts) mutation of the tumor suppressor gene lethal(3)malignant brain tumor (l(3)mbt) causes in a single step the malignant transformation of the adult optic neuroblasts and ganglion mother cells in the larval brain at the restrictive temperature of 29 degrees C. The transformed cells are differentiation-incompetent and grow autonomously in a lethal and invasive fashion in situ in the brain as well as after transplantation in vivo into wild-type adult hosts. The imaginal discs show epithelial overgrowth. At the permissive temperature of 22 degrees C development is completely normal. The ts-period of gene activity responsible for 100% brain tumor sup…
Gallivanting Round the Globe: Translating National Identities in Henry V
2012
In this article we shall be looking at the character of MacMorris in Henry V, and at his small but important role in the four captains’ scene. We shall explore some of the historical, cultural, political, dramaturgical and linguistic complexities of his portrayal of Irishness as a necessary preliminary study to its translation into other languages, both for the printed page and for the stage. Spanish and Catalan translations of the scene will be briefly analysed in what we hope will be the framework of a wider, multilingual preoccupation: how does national identity translate in a global context? How does —or can— MacMorris speak in other languages?
Dimensions of National Culture – Cross-cultural Theories
2019
Abstract Over the past three decades, after Hofstede presented his proposal about cultural differences, many authors have presented their dimensions of national culture. The aim of this article is to give a synthesis of the proposal from significant authors and show a set of models of cultural dimensions based on theoretical and pragmatic analysis such as models of Hofstede, Trompenaars, GLOBE, Inglehart, Schartz. Also, examples used in this paper help more to understand the importance of research national culture.