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showing 10 items of 1480 documents

Randomized study of subcutaneous low molecular weight heparin plus aspirin versus intravenous immunoglobulin in the treatment of recurrent fetal loss…

2003

Objective To compare the 2 most efficacious therapeutic regimens, intravenous immunoglobulin (IVIG) and anticoagulation with low molecular weight (LMW) heparin plus low-dose aspirin, in women with recurrent pregnancy loss associated with antiphospholipid antibodies (aPL). Methods We examined 40 women with recurrent abortion (at least 3 occurrences) and repeatedly positive test results for anticardiolipin or lupus anticoagulant. The subjects were randomly assigned to treatment with IVIG or LMW heparin plus low-dose aspirin. Both therapies were started when the women were pregnant as documented by a positive urine test. IVIG was stopped at the thirty-first week of gestation, aspirin at the th…

Adultmedicine.medical_specialtyAbortion HabitualAdolescentmedicine.drug_classImmunologyLow molecular weight heparinGastroenterologyRoute of administrationRandom AllocationRheumatologyAntiphospholipid syndromePregnancyInternal medicinemedicineImmunology and AllergyHumansPharmacology (medical)PregnancyLupus anticoagulantAspirinAspirinbusiness.industryAnticoagulantPregnancy OutcomeAnticoagulantsImmunoglobulins IntravenousHeparinHeparin Low-Molecular-Weightmedicine.diseaseAntiphospholipid SyndromeSurgeryPregnancy ComplicationsTreatment OutcomeDrug Therapy CombinationFemalebusinessmedicine.drugArthritis and rheumatism
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Results of closed subtalar dislocations.

2015

Background The subtalar dislocation (SD) of the foot is an uncommon injury characterized by a simultaneous dislocation of talocalcaneal and talonavicular joints without involvement of the tibiotalar and calcaneocuboid joints. Purposes The purpose of this study was to evaluate the clinical and radiological outcome in a consecutive series of close SD. Methods We retrospectively evaluated a case series of patients who presented a close SD. Thirteen patients were selected for this study. There were 9 patients with a medial SD, 3 patients with a lateral dislocation and 1 patient with a posterior subtalar dislocation. Results The most frequent symptoms observed in our study included transient mil…

Adultmedicine.medical_specialtyAdolescentRadiographyJoint Dislocations03 medical and health sciencesYoung Adult0302 clinical medicineFoot traumaPeritalar dislocationSettore MED/33 - Malattie Apparato LocomotoremedicineHumansOrthopedics and Sports MedicineJoint dislocationAnkle dislocationFoot InjuriesAgedRetrospective StudiesAged 80 and over030222 orthopedicsbusiness.industryRetrospective cohort study030229 sport sciencesMiddle Agedmedicine.diseaseSubtalar dislocationSurgeryRadiographymedicine.anatomical_structureRadiological weaponOrthopedic surgerySurgeryFoot InjuryAnkleDislocationbusinessMusculoskeletal surgery
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Congenital hyperthyroidism with reciprocal translocation t(1;17)(q25;q21)

1989

The authors report a case of 1;17 translocation and request contact with colleagues who have observed similar cases.

Adultmedicine.medical_specialtyChromosomal translocationBiologyHyperthyroidismTranslocation GeneticCongenital hyperthyroidismEndocrinologyChromosomes Human Pair 1KaryotypingInternal medicineGeneticsmedicineHumansFemaleGenetics (clinical)Chromosomes Human Pair 17Human Genetics
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Primary site disease and recurrence location in ovarian cancer patients undergoing primary debulking surgery vs. interval debulking surgery

2020

Introduction: The natural history and patterns of ovarian cancer (OC) relapse are still unclear. Recurrent disease can be peritoneal, parenchymal, or nodal. This study aims to analyze the location and pattern of OC recurrence according to the primary site of disease and to the type of surgical approach used. Material and methods: All OC patients underwent primary debulking surgery (PDS) or interval debulking surgery (IDS), with 2014 FIGO stage III-IV, and with platinum-sensitive recurrence were included in the study. Primary disease location and site of recurrences were divided into peritoneal, parenchymal, and nodal, according to the presence of peritoneal carcinomatosis, parenchymal metas…

Adultmedicine.medical_specialtyDiseaseMetastasis03 medical and health sciences0302 clinical medicineOvarian cancerRecurrenceMedicineHumans030212 general & internal medicineStage (cooking)Nodal involvementAgedOvarian Neoplasmsbusiness.industryGeneral MedicineCytoreduction Surgical ProceduresMiddle Agedmedicine.diseaseDebulkingSite of recurrencePeritoneal carcinomatosisSurgeryNatural historyNeoplasm RecurrenceOncologyLocalPrimary site location030220 oncology & carcinogenesisSurgeryFemaleNeoplasm Recurrence LocalPattern of recurrencebusinessOvarian cancer
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Preimplantation genetic diagnosis by fluorescence in situ hybridization: clinical possibilities and pitfalls.

2003

Preimplantation genetic diagnosis using the fluorescence in situ hybridization technique (FISH) is being used widely to prevent the transmission of sex-linked diseases, to screen for translocations, and for aneuploidy screenng in specific invitro fertilization (IVF) patient groups, along with FISH analysis of spematozoa in intertile men. In this study, we aim to critically analyze our clinical results in patients at risk of transmitting sex-linked diseases (n = 55), in carriers of translocations (n = 43), in women who have recurent miscarriage (two or more miscarriages) (n = 128), recurrent IVF failure (three or more failed IVF attempts) (n = 47), and patients of advanced maternal age (37 y…

Adultmedicine.medical_specialtyGenetic LinkagePregnancy High-RiskAneuploidyFertilization in VitroBiologyPreimplantation genetic diagnosisTranslocation GeneticMiscarriageRecurrent miscarriagemedicineHumansAdvanced maternal ageTreatment FailureIn Situ Hybridization FluorescencePreimplantation DiagnosisGynecologyPregnancySex Chromosomesmedicine.diagnostic_testIncidence (epidemiology)Genetic Diseases InbornObstetrics and Gynecologymedicine.diseaseAbortion SpontaneousFemaleFluorescence in situ hybridizationMaternal AgeJournal of the Society for Gynecologic Investigation
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Traumatic atlanto-axial rotatory subluxation after surgical correction of prominent ears: Case report and review of the literature

2019

International audience; Corrective surgery of prominent ears may be justified for social or aesthetic reasons during childhood or adulthood. Post-operative complications occur in approximately 0 to 8.4% of cases. This case describes a rare atlanto-axoid rotatory subluxation after bilateral surgical correction of prominent ears under general anesthesia. Orthopedic treatment was done after two months of medical roaming outside of our center. The one-year post-operative clinic consultation and radiological exam were normal. Only the psychological impact of the episode remained. Traumatic atlanto-axial rotatory subluxation is a rare complication but should be considered after post-operative tor…

Adultmedicine.medical_specialtyJoint Dislocations[SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/SurgeryEsthetics Dental03 medical and health sciences0302 clinical medicinemedicineHumansChild030223 otorhinolaryngologyTorticollisSubluxationbusiness.industryGeneral surgerySurgical correctionmedicine.disease3. Good healthProminent earsProminent earsAtlanto-Axial JointOtorhinolaryngologyRadiological weaponOrthopedic surgeryOtoplastySurgeryOral SurgeryTomography X-Ray ComputedbusinessComplicationOtoplasty030217 neurology & neurosurgeryTorticollisAtlanto-axial subluxation
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Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a pa…

2020

Summary The ongoing COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 is a global public health crisis. Multiple observations indicate poorer post-infection outcomes for patients with cancer than for the general population. Herein, we highlight the challenges in caring for patients with acute leukaemias and myeloid neoplasms amid the COVID-19 pandemic. We summarise key changes related to service allocation, clinical and supportive care, clinical trial participation, and ethical considerations regarding the use of lifesaving measures for these patients. We recognise that these recommendations might be more applicable to high-income countries and might not be general…

Adultmedicine.medical_specialtyMyeloidCoronavirus disease 2019 (COVID-19)Pneumonia ViralPopulationCovid 19 hematological neoplasia managementMEDLINEArticleResource AllocationBetacoronavirus03 medical and health sciences0302 clinical medicinePandemicHumansMedicineDisease management (health)Intensive care medicineeducationExpert TestimonyPandemicsInfection Controleducation.field_of_studyLeukemiaMyeloproliferative DisordersSARS-CoV-2business.industryPublic healthCOVID-19Disease ManagementHematology3. Good healthClinical trialmedicine.anatomical_structure030220 oncology & carcinogenesisPractice Guidelines as TopicCoronavirus Infectionsbusiness030215 immunology
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Improved short-term outcomes of kidney transplants in controlled donation after the circulatory determination of death with the use of normothermic r…

2021

Normothermic Regional Perfusion (NRP) allows the in situ perfusion of organs with oxygenated blood in donation after the circulatory determination of death (DCDD). We aimed at evaluating the impact of NRP on the short-term outcomes of kidney transplants in controlled DCDD (cDCDD). This is a multicenter, nationwide, retrospective study comparing cDCDD kidneys obtained with NRP versus the standard rapid recovery (RR) technique. During 2012-2018, 2,302 cDCDD adult kidney transplants were performed in Spain using NRP (n=865) or RR (n=1,437). The study groups differed in donor and recipient age, warm and cold ischemic time and use of ex situ machine perfusion. Transplants in the NRP group were m…

Adultmedicine.medical_specialtyTissue and Organ Procurementdonors and donationdelayed graft function (DGF)graft survivalnephrologyUrologykidney transplantationorgan procurement and allocationRegional perfusion030230 surgery03 medical and health sciences0302 clinical medicineHumansImmunology and AllergyMedicinePharmacology (medical)Retrospective StudiesTransplantationKidneyMachine perfusionorgan perfusion and preservationbusiness.industryGraft SurvivalRetrospective cohort studyOrgan PreservationKidney TransplantationTissue DonorspracticeDelayed Graft FunctionDeathPerfusionmedicine.anatomical_structureclinical researchDonationPropensity score matchingCirculatory systembusinessdonation after circulatory death (DCD)
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Efficacy of eminectomy in the treatment of prolonged mandibular dislocation

2009

Surgery of the temporomandibular joint is indicated for different clinical situations, including internal derangements, hipomobility, hipermobility, pathology and trauma. Mandibular dislocation is an acute painful condition that causes severe functional limitation. Manual reduction, with or without pharmacological assistance, is the treatment of choice and should be performed as early as possible. On rare situations mandibular dislocation may not be perceived by the patient and remain undiagnosed or misdiagnosed for a long period. This may include severe illness, neurological diseases and prolonged intensive care hospitalization with oral intubation and sedation. Treatment of prolonged mand…

Adultmedicine.medical_specialtymedicine.medical_treatmentSedationJoint DislocationsManual reductionCondylestomatognathic systemIntensive careDislocation (syntax)HumansMedicineIntubationOrthopedic ProceduresGeneral DentistryTemporomandibular Jointbusiness.industryTemporal Bone:CIENCIAS MÉDICAS [UNESCO]SurgeryTemporomandibular jointmedicine.anatomical_structureOtorhinolaryngologyAnesthesiaUNESCO::CIENCIAS MÉDICASChronic DiseaseFemaleSurgerymedicine.symptombusinessOrthopedic ProceduresMedicina Oral Patología Oral y Cirugia Bucal
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Robust consensus in social networks and coalitional games

2014

We study an n-player averaging process with dynamics subject to controls and adversarial disturbances. The model arises in two distinct application domains: i) coalitional games with transferable utilities (TU) and ii) opinion propagation. We study conditions under which the average allocations achieve robust consensus to some predefined target set.

Adversarial systemMathematical optimizationProcess (engineering)Game theory networks allocations robust receding horizon control.EconomicsSettore MAT/09 - Ricerca OperativaSet (psychology)Mathematical economicsGame theory
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