Search results for "Lps"
showing 10 items of 120 documents
Lipopolysaccharides and glucagon-like peptide 1 : from molecular mechanisms to pathophysiology
2016
Obesity and type 2 diabetes are metabolic diseases which have reached epidemic proportions worldwide. These metabolic disorders are related to a low grade inflammation whose molecular origin is still unknown. Previous studies have highlighted the involvement of the gut microbiota and especially components of the cell wall of Gram(-) bacteria: lipopolysaccharides (LPS). We have recently shown that LPS enhance glucagon-like peptide 1 (GLP-1) plasma levels, a hormone which is known to stimulate insulin secretion. Moreover there would be a link between the nutritional qualities of food and LPS plasma levels. Thus diet, LPS and GLP-1 may be closely related. The present work focuses on i) the mol…
Détection orosensorielle des lipides alimentaires chez la souris : mécanismes impliqués et altérations au cours de l'obésité
2015
Dietary lipids are detected by the gustatory system in rodents and humans. Two candidate lipid-receptors are found in taste buds: CD36, which is involved in the fat taste as shown by studies conducted in our laboratory, and GPR120. Our results show that GPR120 is not directly involved in the gustatory detection of lipids in mice, but could rather be involved in the modulation of the sensitivity for fat. When this gustatory system works properly, food choices can meet the organism’s energy needs. Besides, the pleasure brought by the consumption of palatable foods is satisfied. However, obese people often overconsume energy-dense food. In the central nervous system, perturbations of the rewar…
Approche archéologique et environnementale des premiers peuplements alpins autour du col du Petit-Saint-Bernard (Savoie -Vallée d’Aoste) : un bilan d…
2008
International audience
Sinemurian to lowermost Toarcian ammonites of the Brescian Prealps (Southern Alps, Italy): preliminary biostratigraphical framework and correlations.
2009
10 pages; International audience; A set of 28 ammonite biohorizons or faunal assemblages is proposed for the Sinemurian, the Pliensbachian and the lowermost Toarcian of the Brescian Prealps, in part based on the published data of the authors of this contribution and partly on new results, derived both from recent field investigations and from the study of the historical collection of Lower Jurassic ammonites preserved in the Museum of Natural Sciences of Brescia (Northern Italy). The biohorizons are present in the Liassic carbonate succession of the Brescian Prealps, cropping out between the eastern surroundings of Brescia (Botticino), to the east, and Lake Iseo, to the west. Since the Hett…
The genetic heritage of Alpine local cattle breeds using genomic SNP data
2020
Abstract Background Assessment of genetic diversity and population structure provides important control metrics to avoid genetic erosion, inbreeding depression and crossbreeding between exotic and locally-adapted cattle breeds since these events can have deleterious consequences and eventually lead to extinction. Historically, the Alpine Arc represents an important pocket of cattle biodiversity with a large number of autochthonous breeds that provide a fundamental source of income for the entire regional economy. By using genotype data from medium-density single nucleotide polymorphism (SNP) arrays, we performed a genome-wide comparative study of 23 cattle populations from the Alpine Arc an…
Policy Makers', NGO, and Healthcare Workers' Accounts of Migrants' and Refugees' Healthcare Access Across Europe : Human Rights and Citizenship Based…
2020
Freely available healthcare, universally accessible to the population of citizens, is a key ideal for European welfare systems. As labor migration of the twentieth century gave way to the globalized streams of the twenty-first century, new challenges to fulfilling these ideals have emerged. The principle of freedom of movement, together with large-scale forced migration have led to large scale movements of people, making new demands on European healthcare systems which had previously been largely focused on meeting sedentary local populations' needs. Drawing on interviews with service providers working for NGOs and public healthcare systems and with policy makers across 10 European countrie…
Un modello dinamico per la simulazione della ionizzazione di terreni non omogenei in presenza di elettrodi disperdenti elevate correnti impulsive
2008
La caratterizzazione elettromagnetica del comportamento dinamico di elettrodi interrati, disperdenti elevate correnti impulsive, costituisce uno degli aspetti primari nella progettazione di un sistema di protezione dalle fulminazioni atmosferiche (LPS). D’altra parte, elevate correnti impulsive possono causare l’insorgere di fenomeni di ionizzazione del terreno, nelle zone prossime agli elettrodi interrati, nei punti in cui il campo elettrico totale supera il valore critico. Modelli teorici e misure sperimentali correlano l’insorgere di variazioni di conducibilità del terreno in prossimità di elettrodi interrati interessati da elevate correnti impulsive al fenomeno della ionizzazione del te…
Approche d'un territoire de montagne : occupations humaines et contexte pédo-sédimentaire des versants du col du Petit-Saint-Bernard, de la Préhistoi…
2014
As part of a multi-year programme, survey campaigns have been carried out on both slopes of the Petit-Saint-Bernard pass (2188 m, western Alps), at an altitude of between 750 and 3000 m. The method employed abandons ground-based surveying in favour of multiple manual surveys carried out on selected topographic contexts down to the base of the Holocene fill. The results obtained document the longterm development of the pedo-sedimentary dynamic and the occupation of the different altitude stages. The significance of the archaeological data collected is discussed in relation to the state of knowledge in a comparison area including the neighbouring valleys of the western Alps, to existing settl…
Simulated Game-Based Ice Hockey Match Design (Scrimmage) Elicits Greater Intensity in External Load Parameters Compared With Official Matches.
2022
ObjectiveA limited number of studies have explored the external load experienced in indoor sports such as ice hockey, and few the link between training and match performance. As a paucity exists within this topic, this study explored whether a simulated match design (i.e., scrimmage) could be representative of official match demands and elicit similar external loads as in official matches in a group of elite youth male ice hockey players.MethodsA total of 26 players were monitored during eight official and four simulation matches using a Local Positioning System. Total distance, max velocity, slow (0–10.9 km/h), moderate (11–16.9 km/h), high (17.0–23.9 km/h), and sprint (>24 km/h) sp…
Sociālpsiholoģiskie aspekti mūsdienu Japānas demogrāfijā
2021
Darba nosaukums ir Sociālpsiholoģiskie aspekti mūsdienu Japānas demogrāfijā. Japānas demogrāfiskā situācija un tās sociālpsiholoģiskie rašanās iemesli tieši ietekmē Japānas sabiedrību, tās kultūrvidi un nācijas nākotni. Sabiedrības novecošanās, dzimstības samazināšanās un valsts sociālekonomiskā stāvoklis rada situāciju Japānas sabiedrībā, kurā jāpieņem lēmumi un jārod risinājumi, kuri tieši ietekmētu veselas nācijas nākotni un uzlabotu sociāldemogrāfisko situāciju valstī. Tādēļ sākotnēji nepieciešams noskaidrot iespējamos procesus un valstiskos lēmumus, kā arī sociālpsiholoģiskos aspektus, kuri pasliktinājuši pašreizējo demogrāfisko situāciju Japānā. Darba mērķis: izpētīt 21. gadsimta Japā…