Search results for "Lua"
showing 10 items of 3286 documents
TCP Performance in Mobile Ad hoc Networks
2013
International audience; In this paper, we present a survey of TCP (Transmission Control Protocol) protocol for better performance in the MANET (Mobile Ad Hoc Network). After a short presentation of the main features of TCP, we give the most important problems from which TCP suffer in MANET. We present after that some approaches proposed in the literature in order to improve its performance. Our paper contains also a performance evaluation of TCP NewReno and TCP Vegas transport protocols under AODV and DSR routing protocols. The simulations are conducted under varying conditions of number of TCP connections, number of nodes and mobility.
BOTANICAL CONTRIBUTION TO ARCHAEOLOGICAL LAND EVALUATION IN THE FP7 MEMOLA PROJECT
2014
Comisión de Test: veinticinco años velando por la calidad de los test
2022
[ES]El objetivo del presente trabajo es mostrar las actividades y proyectos llevados a cabo por la Comisión de Test del Consejo General de Psicología de España para mejorar la calidad y el uso de los test. Se repasan los proyectos más relevantes de la comisión durante sus veinticinco años de existencia, describiendo los trabajos llevados a cabo para a) conocer las opiniones y actitudes de los psicólogos hacia los test, b) evaluar la calidad de los test editados en España, y c) desarrollar estándares, directrices y códigos éticos y deontológicos que mejoren la práctica de los test. También se resaltan otras actividades de la comisión de carácter formativo, así como sus relaciones con otras o…
Revisión del modelo para evaluar la calidad de los tests utilizados en España
2016
Para usar adecuadamente los tests, es necesario que los profesionales cuenten con información rigurosa de su calidad. Es por ello que, desde hace unos años, se viene aplicando el modelo español de evaluación de la calidad de los tests (Prieto y Muñiz, 2000). El objetivo de este trabajo es actualizar y revisar dicho modelo, con el fin de incorporar las recomendaciones hechas en sus aplicaciones, y para incorporar los avances psicométricos y tecnológicos que se han producido durante los últimos años. El modelo original fue revisado en varias fases, y la revisión originalmente propuesta fue revisada por un conjunto de expertos, lo que dio lugar a la versión final que se describe en este trabaj…
Calidad de vida : evaluación y trastornos del espectro del autismo
2013
espanolEn este articulo se muestran las conclusiones de la investigacion "senda hacia la participacion", desarrollada por la Asociacion Autismo Burgos, analizando los resultados de la aplicacion de cuatro instrumentos para evaluar la calidad de vida en una muestra de veinticuatro personas con Trastorno del Espectro del Autismo (tea). Los resultados obtenidos reflejan las dificultades de estos instrumentos para medir la calidad de vida de las personas con tea, limitaciones que nos llevan a construir una guia de indicadores de calidad de vida, en colaboracion con los padres de la Asociacion. La guia se realizo a traves de un grupo focal del que participaron trece padres, dirigido por dos prof…
Biological Evaluation of the Antiproliferative and Anti-migratory Activity of a Series of 3-(6-Phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)-1H-indole …
2019
Heterocyclic rings are recognized as key components of many natural, semi-synthetic and synthetic molecules with a broad spectrum of biological activities. Among these molecules, the indole and imidazo[2,1-b][1,3,4]thiadiazole systems have recently been described as useful scaffolds for the design of anticancer agents. Herein the antitumor activity of a series of 3-(6-phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)-1H-indoles, designed as hybrid structures, was assessed. Seven out of 10 compounds (1a-g) were submitted to National Cancer Institute (NCI). Remarkably, compound 1g showed antiproliferative activity against the full panel of sixty human cancer lines, with half-maximal inhibitory conc…
Translation of genomics-guided RNA-based personalised cancer vaccines: towards the bedside
2014
Cancer is a disease caused by DNA mutations. Cancer therapies targeting defined functional mutations have shown clinical benefit. However, as 95% of the mutations in a tumour are unique to that single patient and only a small number of mutations are shared between patients, the addressed medical need is modest. A rapidly determined patient-specific tumour mutation pattern combined with a flexible mutation-targeting drug platform could generate a mutation-targeting individualised therapy, which would benefit each single patient. Next-generation sequencing enables the rapid identification of somatic mutations in individual tumours (the mutanome). Immunoinformatics enables predictions of mutat…
Analyse économique des essais cliniques internationaux en cancérologie
2018
International audience; In oncology, as in other fields of medicine, international multicentre clinical trials came into being so as to include a sufficient number of subjects to investigate a clinical situation. The existence of tight budgetary constraints and the desire to make the best use of the resources available have resulted in the development of economic evaluations associated with these trials, which, thanks to their level of evidence and their size, provide particularly relevant material. Nonetheless, economic evaluations alongside international clinical trials raise specific questions of methodology with regard to both the design and the analysis of the results. Indeed, the cost…
Erythropoietin restores the anemia-induced reduction in radiosensitivity of experimental human tumors in nude mice
2003
Abstract Purpose The effect of recombinant human erythropoietin (rhEPO) on the radiosensitivity of human tumor xenografts growing in anemic and nonanemic nude mice was studied. Methods and materials Anemia was induced by total body irradiation ([TBI], 2 × 4 Gy) of mice before tumor implantation into the subcutis of the hind leg. The development of anemia was prevented by rhEPO (750 U/kg s.c.) given 3 times weekly starting 2 weeks before TBI. Fourteen days after fractionated TBI (tumor volume of approx. 40 mm 3 ), single-dose irradiation of the tumor with varying doses was performed so that in full dose–response relationship for the probability of tumor cure was obtained. Results Radiation-i…
Children may not benefit from neuroblastoma screening at 1 year of age. Updated results of the population based controlled trial in Germany
2003
Neuroblastoma is the second most frequent malignancy in childhood. We investigated whether screening for neuroblastoma at 1 year of age reduces the incidence of metastatic disease or mortality. Screening was offered in 6 of the 16 German states from 1995 to 2000 with the remaining states serving as controls. We studied 2,581,188 children in the screening area born between 1994 and 1999 and 2,117,600 in the control area. We compared mortality from neuroblastoma and the incidence of disseminated disease in the two groups. The screened group and the control group had similar rates of stage 4 neuroblastoma and mortality due to neuroblastoma. Comparison of the screened group and the control area…