Search results for "Lute"
showing 10 items of 1384 documents
Low-dose dopamine agonist administration blocks vascular endothelial growth factor (VEGF)-mediated vascular hyperpermeability without altering VEGF r…
2006
No specific treatment is available for ovarian hyperstimulation syndrome (OHSS), the most important complication in infertile women treated with gonadotropins. OHSS is caused by increased vascular permeability (VP) through ovarian hypersecretion of vascular endothelial growth factor (VEGF)activating VEGF receptor 2 (VEGFR-2). We previously demonstrated in an OHSS rodent model that increased VP was prevented by inactivating VEGFR-2 with a receptor antagonist(SU5416).However,duetoitstoxicity(thromboembolism) and disruption of VEGFR-2-dependent angiogenic processes critical for pregnancy, this kind of compound cannot be used clinically to prevent OHSS. Dopamine receptor 2 (Dp-r2) agonists, use…
Absolute and monotonic norms
1961
Insights into the decomposition pathway of a lutetium alkylamido complex via intramolecular C–H bond activation
2017
Abstract Synthesis, characterization and reaction chemistry of lutetium alkylamido LLu(CH2SiMe3)(NHCPh3) (2), L = 2,5-[Ph2P=N(4-iPrC6H4)]2N(C4H2)–, is reported. Complex 2 undergoes cyclometalation of the NHCPh3 ligand at elevated temperatures to produce the orthometalated complex LLu(κ2−N,C-(NHCPh2(C6H4))) (3) which converts to 0.5 equivalents of bis(amido) LLu(NHCPh3)2 (4) upon heating at 80 °C for 24 h. Reaction of complex 2 with 4-dimethylaminopyridine (DMAP) does not promote alkane elimination nor imido formation. A kinetic analysis of the thermal decomposition of complex 2, supported by deuterium labelling studies and computational analysis (PBE0/def2-TZVP/SDD(Lu)), indicate direct Csp…
La pandemia da COVID-19: mutamento e persistenze
2022
L’analisi dei documenti prodotti in Italia sul tema dell’accesso alle terapie intensive durante la pandemia da COVID-19 indica che la riflessione sulle questioni di accesso alle risorse drammaticamente limitate nel nostro Paese è ancora molto acerba e meriterebbe lavori di indagine più accurata e approfondita con un contributo multidisciplinare. Bioetica. Rivista interdisciplinare ha contribuito alla maturazione e alla crescita delle conoscenze in questo ambito, con la pubblicazione di diversi articoli. Tale apertura verso i temi di giustizia distributiva mostra la capacità della rivista di cogliere e affrontare i temi emergenti nel dibattito bioetico italiano, mostra il suo sapere essere “…
Modular P-Chirogenic Phosphine-Sulfide Ligands: Clear Evidence for Both Electronic Effect and P-Chirality Driving Enantioselectivity in Palladium-Cat…
2015
Using the ephedrine methodology, modular stereoselective syntheses of a new class of P-chirogenic phosphines bearing a sulfur-chelating arm (P*,S-hybrid ligand) are described. A first series of syntheses based on a Fries-like rearrangement of P-chirogenic phosphinite-boranes, which are prepared from 2-bromobenzyl or 2-bromophenethyl alcohol and are mediated by metal–halide exchange, have been performed. This rearrangement affords phosphine-boranes stereospecifically with an o-hydroxyalkylphenyl substituent. The latter residue is subsequently converted into a sulfur-containing group. In a second series, the stereoselective syntheses were achieved according to a new strategy involving a react…
MODELLISTICA MATEMATICA E PIATTAFORME INFORMATICHE A SUPPORTO DELLA RICERCA AMBIENTALE
2021
La modellizzazione matematica è diventata ormai uno strumento essenziale nell’avanzamento delle conoscenze in qualsiasi campo della scienza, dall’econometria alla psicologia, dalla chimica all’epidemiologia, come vissuto di recente nella pandemia da SARS-coV-2. Anche quelle che erano una volta discipline “soft” come la biomedicina o l’ecologia possono ora usufruire di tecniche di rappresentazione ed esplicazione dei processi estremamente utili alla comprensione delle dinamiche in gioco. Questa evoluzione, dovuta in non piccola parte all’attuale disponibilità di abbondante potenza di calcolo elettronico a costi ridotti, non è però opera ed appannaggio soltanto della nostra generazione. Lo st…
Thermochemical properties of small open-shell systems: experimental and high-levelab initioresults for NH2and
2006
The first adiabatic ionization energy and the first singlet–triplet splitting of the amidogen radical (NH2) have been determined by high-level ab initio quantum chemistry based on the coupled-cluster approach (90 041 and 10 319 cm−1, respectively) and by high-resolution pulsed-field-ionization zero-kinetic-energy (PFI-ZEKE) photoelectron spectroscopy (90 083.8 ± 1.0 and 10 222.0 ± 1.3 cm−1, respectively). A comparison between the theoretical and experimental values demonstrates the predictive powers of high-level ab initio theory in the derivation of the thermochemical properties of small molecular systems. The absolute accuracy of better than 100 cm−1 alleviates the experimental search for…
On the enhancement of diffusion by chaos, escape rates and stochastic instability
1999
We consider stochastic perturbations of expanding maps of the interval where the noise can project the trajectory outside the interval. We estimate the escape rate as a function of the amplitude of the noise and compare it with the purely diffusive case. This is done under a technical hypothesis which corresponds to stability of the absolutely continuous invariant measure against small perturbations of the map. We also discuss in detail a case of instability and show how stability can be recovered by considering another invariant measure.
New n-type molecular semiconductor–doped insulator (MSDI) heterojunctions combining a triphenodioxazine (TPDO) and the lutetium bisphthalocyanine (Lu…
2018
International audience; Molecular semiconductor–doped insulator (MSDI) heterojunctions were designed using a new family of sublayers, namely triphenodioxazines (TPDO). The device obtained by combining the tetracyano triphenodioxazine bearing two triisopropylsilylethynyl moieties as a sublayer with the lutetium bisphthalocyanine (LuPc2) as a top layer showed a nonlinear current–voltage characteristic independent of the sign of the polarization, which is the signature of MSDI heterojunctions. Thus, a TPDO was used in a chemical sensor for the first time. Despite LuPc2 being the only material exposed to the atmosphere, the positive response of the device under ammonia revealed the key role pla…
NiO diluted in high surface area TiO2 as efficient catalysts for the oxidative dehydrogenation of ethane
2017
[EN] Catalysts consisting of NiO diluted in high surface area TiO2 can be as efficient in the oxidative dehydrogenation of ethane as the most selective NiO-promoted catalysts reported previously in the literature. By selecting the titania matrix and the NiO loading, yields to ethylene over 40% have been obtained. In the present article, three different titanium oxides (TiO2) have been employed as supports or diluters of nickel oxide and have been tested in the oxidative dehydrogenation of ethane to ethylene. All TiO2 used present anatase as the main crystalline phase and different surface areas of 11,55 and 85 m(2) g(-1). It has been observed that by selecting an appropriate nickel loading …