Search results for "Lysine"

showing 10 items of 170 documents

Effect of storage conditions on furosine formation in milk-cereal based baby foods

2008

[EN] The effect of storage during 9 months at 25, 30 and 37 degrees C on furosine formation in three milk-cereal based baby foods was studied to evaluate development of the Maillard reaction. Furosine was measured by HPLC-UV. Immediately after the manufacturing process, furosine contents were 310-340 mg/100 g protein and at the 9th storage month were 426-603 mg/100 g protein. Storage time and temperature have a significant increase (p < 0.05) of furosine content during storage. Furosine contents were higher in sample containing honey than in those without honey. Interactions (p < 0.05) between storage time and temperature or type of sample were found. A predictive model equation of the evol…

ChromatographyChemistryManufacturing processESTADISTICA E INVESTIGACION OPERATIVAFood preservationStorageGeneral MedicineAnalytical ChemistryWarehouseMaillard reactionMaillard reactionsymbols.namesakeFurosinesymbols; Maillard reactionFood scienceBaby foodsFood ScienceLysine blockage
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Effects of thermal processing and storage on available lysine and furfural compounds contents of infant formulas.

2000

The Maillard reaction-related effects that thermal treatments during the manufacturing process and storage (at 20 and 37 degrees C) have on powdered adapted and follow-up milk-based infant formulas were estimated by measuring the available lysine and furfural compounds contents of raw cow milk used in manufacturing, intermediate products and formulas. A fluorimetric method was used to measure the available lysine contents, and free and total furfural compounds were determined by HPLC. Statistically significant losses in available lysine (about 20%) in the infant formulas with respect to raw milk were found. The storage period did not affect the available lysine contents of adapted formulas …

ChromatographyFood HandlingLysineLysineGeneral ChemistryRaw milkFurfuralHigh-performance liquid chromatographyCow milkchemistry.chemical_compoundMaillard reactionsymbols.namesakechemistryMethyl KetonesymbolsFuraldehydeInfant FoodFood scienceGeneral Agricultural and Biological SciencesHydroxymethylfurfuralJournal of agricultural and food chemistry
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Comparison of the efficacy of chemomechanical caries removal (Carisolv') with that of conventional excavation in reducing the cariogenic flora

2004

Summary.  Objectives.   The usage of minimally invasive procedures and attention to patient comfort are of great importance, especially for dental treatment in small children. This has led to the development of chemomechanical methods for caries removal. The aim of this study was to compare the efficacy of chemomechanical caries removal with that of conventional excavation in reducing the count of the cariogenic flora. Design and setting.  Subjects for this study were chosen from children admitted to dental clinic for restorative procedures under general anaesthesia. Samples and methods.  Twenty-one children (mean age 43·5 ± 12·0 months) with early childhood caries were included in this stu…

Colony Count MicrobialGlutamic AcidDentistryDental CariesBacterial countsstomatognathic systemLeucinemedicineHumansChildGeneral DentistryMinimally invasive proceduresPatient comfortBacteriabusiness.industryLysineMean agemedicine.diseaseLactobacillusstomatognathic diseasesDental clinicChild PreschoolDentinMicroscopy Electron ScanningDental Cavity PreparationTotal bacterial countbusinessCaries RemovalEarly childhood cariesInternational Journal of Paediatric Dentistry
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Designer membraneless organelles enable codon reassignment of selected mRNAs in eukaryotes.

2019

How to make an organelle in eukaryotes A key step in the evolution of complex organisms like eukaryotes was the organization of specific tasks into organelles. Reinkemeier et al. designed an artificial, membraneless organelle into mammalian cells to perform orthogonal translation. In response to a specific codon in a selected messenger RNA, ribosomes confined to this organelle were able to introduce chemical functionalities site-specifically, expanding the canonical set of amino acids. This approach opens possibilities in synthetic cell engineering and biomedical research. Science , this issue p. eaaw2644

Computer scienceComputational biology010402 general chemistryProtein Engineering01 natural sciencesGenomeArticle03 medical and health sciencesSynthetic biologyRNA TransferOrganelleChlorocebus aethiopsAnimalsHumansRNA MessengerCaenorhabditis elegansCodon030304 developmental biologyOrganelles0303 health sciencesMultidisciplinaryLysineHEK 293 cellsCell MembraneRNAProtein engineeringGenetic code0104 chemical sciencesHEK293 CellsGenetic CodeProtein BiosynthesisCOS CellsMethanosarcinaSynthetic BiologyRibosomesArtificial OrganellesScience (New York, N.Y.)
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Auto-assembly of nanometer thick, water soluble layers of plasmid DNA complexed with diamines and basic amino acids on graphite: Greatest DNA protect…

2017

Abstract We have investigated the ability of diamines as well as basic amino acids to condense DNA onto highly ordered pyrolytic graphite with minimum damage after re-dissolution in water. Based on a bibliographic survey we briefly summarize DNA binding properties with diamines as compared to basic amino acids. Thus, solutions of DNA complexed with these linkers were drop-cast in order to deposit ultra-thin layers on the surface of HOPG in the absence or presence of Tris buffer. Atomic Force Microscopy analyses showed that, at a fixed ligand-DNA mixing ratio of 16, the mean thickness of the layers can be statistically predicted to lie in the range 0–50 nm with a maximum standard deviation ±…

DNA protectionTrisStereochemistryLysineBioengineering02 engineering and technology010402 general chemistryArginine01 natural sciencesBiomaterialschemistry.chemical_compoundX-ray photoelectron spectroscopyPyrolytic carbonGraphitechemistry.chemical_classificationChemistryDNA021001 nanoscience & nanotechnology0104 chemical sciencesAmino acidCrystallographyMechanics of MaterialsNanoparticlesGraphite0210 nano-technologyDNAPlasmidsMaterials scienceengineering. C, Materials for biological applications
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Vibrio ponticus sp. nov., a neighbour of V fluvialis-V. furnissii clade, isolated from gilthead sea bream, mussels and seawater.

2004

A new Vibrio species, Vibrio ponticus, is proposed to accommodate four marine bacteria isolated from sea water, mussels and diseased sea bream (Sparus aurata), at the Mediterranean coast of Spain. Strains are Gram negative, slightly halophilic bacteria that require Na+ ion for growth, oxidase and catalase positive, negative for arginine dihydrolase and ornithine decarboxylase but positive for lysine decarboxylase and indole, and utilize beta-hydroxybutyrate as a sole carbon source. Phylogenetic analysis locate these marine bacteria in the vicinity of the V. fluvialis-V. furnissii clade, sharing with these two species 16S rDNA sequence similarities slightly above 97% (97.1 and 97.3%, respect…

DNA BacterialIndolesCarboxy-LyasesHydrolasesMolecular Sequence DataBiologyOrnithine DecarboxylaseApplied Microbiology and BiotechnologyMicrobiologyDNA RibosomalMicrobiologyMarine bacteriophageVibrionaceaeVibrio InfectionsRNA Ribosomal 16SSequence Homology Nucleic AcidMediterranean SeaAnimalsSeawaterRibosomal DNAEcology Evolution Behavior and SystematicsPhylogenyVibrioLysine decarboxylase3-Hydroxybutyric AcidFatty AcidsNucleic Acid HybridizationSequence Analysis DNA16S ribosomal RNAbiology.organism_classificationCatalaseVibrioSea BreamBivalviaSpainVibrio InfectionsPhenazinesGentian VioletOxidoreductasesBacteriaSystematic and applied microbiology
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The glycosyltransferase activities of lysyl hydroxylase 3 (LH3) in the extracellular space are important for cell growth and viability.

2008

Abstract Lysyl hydroxylase (LH) isoform 3 is a post-translational enzyme possessing LH, collagen galactosyltransferase (GT) and glucosyltransferase (GGT) activities. We have demonstrated that LH3 is found not only intracellularly, but also on the cell surface and in the extracellular space, suggesting additional functions for LH3. Here we show that the targeted disruption of LH3 by siRNA causes a marked reduction of both glycosyltransferase activities, and the overexpression of LH3 in HT-1080 cells increases hydroxylation of lysyl residues and the subsequent galactosylation and glucosylation of hydroxylysyl residues. These data confirm the multi-functionality of LH3 in cells. Furthermore, t…

DNA ComplementaryGlycosylationCell SurvivalLysyl hydroxylaseCellhydroxylysyl glycosylationFluorescent Antibody Techniquelysyl hydroxylaseMicrotubulesPermeabilityCell LineGlycosyltransferasemedicineExtracellularAnimalsHumanscell growthViability assayRNA Small InterferingCell Shapecell viabilityCell ProliferationbiologyCell DeathCell growthProcollagen-Lysine 2-Oxoglutarate 5-Dioxygenasecollagen biosynthesisGlycosyltransferasesCell BiologyArticlesGalactosyltransferasesMolecular biologyPeptide FragmentsCulture MediaActin Cytoskeletonmedicine.anatomical_structurepost-translational modificationCell culturebiology.proteinMolecular MedicineGlucosyltransferaseExtracellular Spacehydroxylysyl glycosyltransferaseJournal of cellular and molecular medicine
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Evaluation of the Fermentation Dynamics of Commercial Baker’s Yeast in Presence of Pistachio Powder to Produce Lysine-Enriched Breads

2019

The present work was carried out to evaluate the microbiological, physicochemical, and sensory characteristics of fortified pistachio breads. Pistachio powder (5% w/w) was added to flour or semolina and fermented by a commercial baker&#8217;s yeast (Saccharomyces cerevisiae). Pistachio powder did not influence the biological leavening of the doughs. The kinetics of pH and total titratable acidity (TTA) during dough fermentation showed that the leavening process occurred similarly for all trials. The concentration of yeasts increased during fermentation and reached levels of 108 CFU/g after 2 h. Pistachio powder decreased the height and softness of the final breads and increased cell density…

Dough fermentationlcsh:TP500-660lysinebiologyChemistrybiological leaveningdigestive oral and skin physiologyLysineSaccharomyces cerevisiaefood and beveragesTitratable acidPlant Sciencelcsh:Fermentation industries. Beverages. Alcoholbiology.organism_classificationBiochemistry Genetics and Molecular Biology (miscellaneous)Yeastbread fortificationcommercial baker’s yeastCell densityFermentationFood sciencepistachio powderSettore AGR/16 - Microbiologia AgrariaFood ScienceLeavening agentFermentation
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A new neuraminic acid derivative and three types of glycopeptides isolated from the Cuvierian tubules of the sea cucumber Holothuria forskali

1973

The Cuvierian tubules of Holothuria forskali Della Chiaje, a sea cucumber found in the Adriatic Sea, were investigated with regard to their carbohydrate moieties. From a Pronase digest of these tubules three types of carbohydrate units were isolated and characterized. 1. A high-molecular-weight glycopeptide fraction was shown to contain sulphated polyfucose, galactosamine, a uronic acid and a previously unknown neuraminic acid derivative. The sulphate was shown by i.r. analysis to be present as an O-ester. The carbohydrate unit was linked O-glycosidically to threonine and serine residues in the polypeptide chain. The hitherto unknown neuraminic acid derivative (Hf-neuraminic acid) was resis…

ElectrophoresisChromatography PaperCarbohydratesUronic acidHydroxylysineBiochemistrychemistry.chemical_compoundSpecies SpecificityNeuraminic acidAnimalsAmino Acid SequenceGlycosidesAmino AcidsThreonineMolecular BiologyFucosechemistry.chemical_classificationHolothuria forskalibiologyGlycopeptidesGlycosideHexosaminesGlycosidic bondCell BiologyHydrogen-Ion ConcentrationSulfuric Acidsbiology.organism_classificationGlycopeptideAmino acidMolecular WeightUronic AcidsBiochemistrychemistryPronaseChromatography GelNeuraminic AcidsChromatography Thin LayerPeptidesEchinodermataBiochemical Journal
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Dynamic evaluation of aggregation and agglutination of red blood cells.

1984

Viscoelastic evaluation of aggregation and agglutination of red blood cells was attempted. A concentric double cylinder viscoelastometer was used for determining the dynamic rigidity modulus and loss modulus of blood sample. The dynamic rigidity modulus of horse blood were measured over a wide range of hematocrit. The relation between the viscoelastic behavior and the erythrocyte sedimentation was examined. The change in the amount of surface charge of enzyme treated red blood cells was qualitatively estimated from the measurements of dynamic viscoelasticity of red blood cells suspension with added poly-L-lysine. The dynamic rigidity modulus of red blood cells agglutinated by adding lectin …

Erythrocyte AggregationErythrocytesPhysiologyModulusNeuraminidaseRigidity (psychology)Blood SedimentationHematocritViscoelasticityPhysiology (medical)Dynamic modulusmedicineConcanavalin AAnimalsHumansPolylysineTrypsinSurface chargeHorsesmedicine.diagnostic_testbiologyChemistryBlood ViscosityElasticityAgglutination (biology)Concanavalin Abiology.proteinBiophysicsCattleRheologyBiorheology. Supplement : the official journal of the International Society of Biorheology
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