Search results for "M.2"

The New TNM Staging System for Thyroid Cancer and the Risk of Disease Downstaging

2018

In October 2016 the American Joint Committee on Cancer (AJCC) published the 8th edition of the AJCC/TNM cancer staging system and it has been introduced in clinical practice since 1st January 2018. The effect of most of the changes in the new edition was the downstaging of a significant number of patients into lower stages, reflecting their low risk of thyroid cancer-related death. One of the most relevant modification refers to the role of the microscopic extra-thyroidal tumor invasion, which is no longer considered as criterion for the classification of T3 tumors. With the present study we want to assess the impact of the changes of the new staging system and therefore we analyzed or casi…

Deformation and mixing of coexisting shapes in neutron-deficient polonium isotopes

2015

Coulomb-excitation experiments are performed with postaccelerated beams of neutron-deficient Po196,198,200,202 isotopes at the REX-ISOLDE facility. A set of matrix elements, coupling the low-lying states in these isotopes, is extracted. In the two heaviest isotopes, Po200,202, the transitional and diagonal matrix elements of the 2+1 state are determined. In Po196,198 multistep Coulomb excitation is observed, populating the 4+1,0+2, and 2+2 states. The experimental results are compared to the results from the measurement of mean-square charge radii in polonium isotopes, confirming the onset of deformation from Po196 onwards. Three model descriptions are used to compare to the data. Calculati…

THE IMPORTANCE OF IDENTIFYING HUMAN RESOURCE’S POTENTIAL AND EVALUATING ITS PERFORMANCES WHEN IMPLEMENTING TOTAL QUALITY MANAGEMENT Case study on the…

2013

Quality is a concept that has various meanings, but we can agree that at the basis of achieving quality from all the points of view, is the quality of the human resources. Implementing a quality management system provides the source of obtaining an organization’s performance. Any modern organization must know how to use all the tools necessary to identify and evaluate human resources performance.

Acomiadament per causes econòmiques: causes i control judicial després de la reforma de 2012

2017

CORTESÍA Y LENGUAS DE ESPECIALIDAD ENTRE LO LOCAL Y LO GLOBAL: EL CASO DE LAS RESEÑAS DE HOTELES EN ESPAÑOL E INGLÉS

2015

El presente trabajo analiza el género de la reseña de hoteles en español y en inglés para explorar la evolución de este género a raíz de su internacionalización. El análisis basado en corpus se realiza a través de una comparación monolingüe y bilingüe contrastiva, observando la distribución de estrategias de atenuación e intensificación (Briz, 2001; Albelda, 2007) de los adjetivos con carga semántica negativa en tres tipos de reseñas: reseñas en español publicadas en plataformas nacionales españolas, reseñas en español publicadas en plataformas internacionales, y reseñas en inglés publicadas en plataformas internacionales. Los resultados cuantitativos demuestran que la difusión global de es…

Zasada specjalności europejskiego nakazu aresztowania i art. 607e § 3 pkt 2 k.p.k. a możliwość ścigania wydanego obywatela polskiego za przestępstwa …

2022

The article addresses the so-called principle of speciality referred to in Article 607e of the Criminal Procedures Code in connection with Article 27 of the Council Framework Decision of 13 June 2002 no. 2002/584/JHA on the European arrest warrant and the surrender procedures between Member States, and the exception to that rule specified in Article 607e § 3, item 2 CPC and Article 27(3)(a) of the EAW Decision. This article also assesses the order of the Appellate Court in Gdańsk of 31 May 2016, case reference II AKzw 921/16, and the argument that the deadline of 45 days referred to in Article 607e § 3, item 2 CPC cannot start to run with respect to a Polish national. The article refers to …

The Different Immune Profiles of Normal Colonic Mucosa in Cancer-Free Lynch Syndrome Carriers and Lynch Syndrome Colorectal Cancer Patients.

2021

ABSTRACT Background and aims Due to the high load of immunogenic frameshift neoantigens, tumors arising in individuals with Lynch syndrome (LS), the most common inherited colorectal cancer (CRC) syndrome, are characterized by a pronounced immune infiltration. However, the immune status of normal colorectal mucosa in LS is not well characterized. We assessed the immune infiltrate in tumor-distant normal colorectal mucosa from LS CRC patients, sporadic microsatellite-unstable (MSI) and microsatellite-stable (MSS) CRC patients, and cancer-free LS carriers. Methods CD3-positive, FOXP3-positive and CD8-positive T cells were quantified in 219, 233 and 201 formalin-fixed paraffin-embedded (FFPE) n…

Contribution of recently measured nuclear data to reactor antineutrino energy spectra predictions

2013

This paper attempts to summarize the actual problematic of reactor antineutrino energy spectra in the frame of fundamental and applied neutrino physics. Nuclear physics is an important ingredient of reactor antineutrino experiments. These experiments are motivated by neutrino oscillations, i.e. the measure of the θ 13 mixing angle. In 2011, after a new computation of the reactor antineutrino energy spectra, based on the conversion of integral data of the beta spectra from 235 U, and 239;241 Pu, a deficit of reactor antineutrinos measured by short baseline experiments was pointed out. This is called the “reactor anomaly”, a new puzzle in the neutrino physics area. Since then, numerous new ex…

Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Sy…

2021

Abstract Purpose To determine impact of risk-reducing hysterectomy and bilateral salpingo-oophorectomy (BSO) on gynecological cancer incidence and death in heterozygotes of pathogenic MMR ( path_MMR ) variants. Methods The Prospective Lynch Syndrome Database was used to investigate the effects of gynecological risk-reducing surgery (RRS) at different ages. Results Risk-reducing hysterectomy at 25 years of age prevents endometrial cancer before 50 years in 15%, 18%, 13%, and 0% of path_MLH1 , path_MSH2 , path_MSH6 , and path_PMS2 heterozygotes and death in 2%, 2%, 1%, and 0%, respectively. Risk-reducing BSO at 25 years of age prevents ovarian cancer before 50 years in 6%, 11%, 2%, and 0% and…

Autoimmune hepatitis triggered by COVID-19

2021

We present the case of a 60-year-old woman with no drug allergies or toxic habits, with hypothyroidism and receiving treatment with levothyroxine.