Search results for "M1"
showing 10 items of 837 documents
Une typologie de la formalisation de l'éthique en entreprise: l'analyse de contenu de 50 documents
2000
The study of corporate ethics reported in this article sheds light on the content and status of 50 formal ethical statements in large France based companies. Content analysis (with SPAD.T software) reveals potentially divergent view among companies as to the primary nature and purpose of a corporate ethics document. On the one hand, codes contain detailed rules and guidelines devoted to employee conduct. Their objective is to make sure that employees strictly abide by the firm's rules. These documents allow to convey standards setting apart which is good or bad. On the other hand, values statements and corporate principles are shorter documents based on the idea of common trust and includin…
A HUMAN RESOURCE ONTOLOGY FOR RECRUITMENT PROCESS
2009
In this paper we propose a model of ontology for the human resource domain. We emphasize the benefits resulting from the application of Semantic Web technologies in the recruitment process. We use currently available standards and classifications to develop a human resource ontology which gives us means for semantic annotation of job postings and applications. Furthermore, we outline the process of semantic matching which improves the quality of query results. Finally, we propose the architecture of an evaluation system based on Semantic Web technologies.
The influence of culture on the economic freedom and the international business
2006
The firms who decide to expand their business in an international environment must modify their management style through international management. Certainly, international management must adapt their on functions to the different framework of the business development. The culture is a cardinally factor, being an essential component in the success equation of multinational companies. The culture, the habits and the attitudes became points of major interests on the global market. Their importance is obvious through numerous "blunders" which find out in international trade and international. For the success of international business the economies must bees free, but the economic freedom is inf…
Datorizēta FM-100 testa izmantošana hromatiskās jutības sliekšņa noteikšanai
2016
Bakalaura darbs ir uzrakstīts latviešu valodā uz 33 lapaspusēm. Tas satur 17 attēlus, 2 tabulas, 29 atsauces uz literatūras avotiem. Mērķis: aprobēt jaunu nodaļa izveidotu (R.Trukša) FM-100 datorizētu testu cilvēkiem ar krāsu redzes defektiem (KRD) un bez KRD un salīdzināt rezultātus ar HRR testu, D-15 testa divām versijām (Farnsworth un Lanthony) un HMC Oculus anomaloskopu. Pētījumā piedalījās 15 cilvēki, no kuriem 3 bija ar KRD. Datorizēta FM-100 testa datu analīzei izmantoja Vingrys & King-Smith metodi. Izmantojot iegūtos datus tika noteiktas normas vērtības, balstoties uz cilvēku bez KRD rezultātiem.
L'audience et l'influence d'une revue mesurée à travers Internet : une application à Finance Contrôle Stratégie
2009
This article aims to show the interest of statistics available on the Internet concerning consultations of abstracts, downloads and citations of articles to assess the attractiveness and influence of a scientific review. This interest is illustrated by the case of the review Finance Contrôle Stratégie on the basis of the statistics provided by Repec and Publish or Perish. Beyond the findings that confirm the good performance of FCS and the usefulness of these statistics for the management of a scientific review, the article also provides insights into the life cycle of an article and the choice of the language of publication.
Sulfur transfer and activation by ubiquitin-like modifier system Uba4•Urm1 link protein urmylation and tRNA thiolation in yeast.
2017
Urm1 is a unique dual-function member of the ubiquitin protein family and conserved from yeast to man. It acts both as a protein modifier in ubiquitin-like urmylation and as a sulfur donor for tRNA thiolation, which in concert with the Elongator pathway forms 5-methoxy-carbonyl-methyl-2-thio (mcm5s2) modified wobble uridines (U34) in anticodons. Using Saccharomyces cerevisiae as a model to study a relationship between these two functions, we examined whether cultivation temperature and sulfur supply previously implicated in the tRNA thiolation branch of the URM1 pathway also contribute to proper urmylation. Monitoring Urm1 conjugation, we found urmylation of the peroxiredoxin Ahp1 is suppre…
HUMAN RESOURCE MANAGEMENT - FROM FUNCTION TO STRATEGIC PARTNER
2013
In most of the organizations, people are now recognized as the vital asset. Their knowledge, skills and abilities must be deployed to the maximum effect if the organization is to become successful. The intangible value of an organization relating to the people it employs and its human resource strategies is gaining recognition and it is generally accepted that this has implications for long-term sustained performance. The recent chances in the economy and the development of new technologies are creating the proper set for a series of other changes regarding the human resource management. The first one refers to the need to respond to the challenges raised by the knowledge workers and the se…
DEFINING ASPECTS OF HUMAN RESOURCE MANAGEMENT STRATEGY WITHIN THE GENERAL STRATEGY OF THE MODERN ORGANIZATION
2013
The field of human resources requires the presence and action of several categories of persons and managerial structures interested in the quality of human resources and the activities developed by them. Besides managers and employees there are also the shareholders, the unions, the customers, the different national or local agencies, the local community, etc., with major interests regarding decisions in the human resources area. In order to harmonize their activities and achieve an optimal perspective within the evolution of Human Resource Management, special attention is paid to the strategy of human resources management. According to many specialists, strategies in the field of Human Res…
Metabolism via arginase or nitric oxide synthase: two competing arginine pathways in macrophages
2014
Macrophages play a major role in the immune system, both as antimicrobial effector cells and as immunoregulatory cells, which induce, suppress or modulate adaptive immune responses. These key aspects of macrophage biology are fundamentally driven by the phenotype of macrophage arginine metabolism that is prevalent in an evolving or ongoing immune response. M1 macrophages express the enzyme nitric oxide synthase (NOS), which metabolizes arginine to nitric oxide (NO) and citrulline. NO can be metabolized to further downstream reactive nitrogen species, while citrulline might be reused for efficient NO synthesis via the citrulline-NO cycle. M2 macrophages are characterized by expression of the…
eIF2α confers cellular tolerance to S. aureus α-toxin
2015
We report on the role of conserved stress-response pathways for cellular tolerance to a pore forming toxin. First, we observed that small molecular weight inhibitors including of eIF2α-phosphatase, jun-N-terminal kinase (JNK), and PI3-kinase sensitized normal mouse embryonal fibroblasts (MEFs) to the small pore forming S. aureus α-toxin. Sensitization depended on expression of mADAM10, the murine ortholog of a proposed high-affinity receptor for α-toxin in human cells. Similarly, eIF2α (S51A/S51A) MEFs, which harbor an Ala knock-in mutation at the regulated Ser51 phosphorylation site of eukaryotic translation initiation factor 2α, were hyper-sensitive to α-toxin. Inhibition of translation w…