Search results for "MAGNETIC RESONANCE"

showing 10 items of 4721 documents

Diastereoselective Synthesis of Dialkylated Bis(phosphino)ferrocenes: Their Use in Promoting Silver-Mediated Nucleophilic Fluorination of Chloroquino…

2017

International audience; The diastereoselective synthesis of dialkylated ferrocenyl bis(phosphane)s bearing aryl, alkyl, and hetero- or polycyclic substituents on the phosphino groups is reported, together with their characterization in the solid state by X-ray structure analysis and in solution by multinuclear NMR spectroscopy. Introduction of various alkyl groups on the ferrocene backbone, namely, tert-butyl, isopropyl, and trimethylsilyl, has a significant influence on the stereoselectivity of the ensuing lithiation/phosphination reactions. Only the introduction of the tert-butyl groups ensures both a high yield and perfect diastereoselectivity, which leads to the exclusive formation of t…

Diastereoselectivitybond formationTrimethylsilylfunctionalized arylone-potelectrophilic fluorinationPhosphanesAlkylationc-h fluorination[CHIM.INOR]Chemical Sciences/Inorganic chemistry010402 general chemistry01 natural sciencesMedicinal chemistryInorganic Chemistrychemistry.chemical_compoundNucleophileFluorinationOrganic chemistryAlkylpolyphosphane ligandsferrocenyl derivativeschemistry.chemical_classificationp-31 nmr010405 organic chemistryArylHalex reactiondirect arylationreductive elimination[ CHIM.INOR ] Chemical Sciences/Inorganic chemistryNuclear magnetic resonance spectroscopySandwich complexes0104 chemical scienceschemistryFerroceneIsopropyl
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Pure cystic groove pancreatitis: endosonographic appearance.

2019

Malemedicine.medical_specialtybusiness.industryGastroenterologyContrast MediaMagnetic Resonance ImagingEndosonographyYoung AdultText miningPancreatitis ChronicMedicineHumansRadiologyGroove pancreatitisPancreatic CystbusinessTomography X-Ray ComputedBiomarkersEndoscopy
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Dynamic MR imaging of breast lesions: correlation with microvessel distribution pattern and histologic characteristics of prognosis.

2006

To evaluate the association of dynamic enhancement parameters of benign and malignant breast lesions at magnetic resonance (MR) imaging with microvessel distribution and histologic prognostic tumor characteristics.Regional review board approval and informed consent were obtained. Surgical resection specimens of breast lesions (32 benign, 86 malignant) in 118 patients (age range, 28-86 years; mean, 58 years) who had undergone dynamic T1-weighted MR imaging of both breasts were included in the study. Different MR enhancement parameters and microvessel density (MVD) distribution were determined. In malignant lesions, TNM stage, tumor grade, proliferative activity, and hormone receptor expressi…

AdultMammary glandBreast NeoplasmsLesionsymbols.namesakemedicineCarcinomaHumansRadiology Nuclear Medicine and imagingStage (cooking)Lymph nodeMicrovesselFisher's exact testAgedAged 80 and overmedicine.diagnostic_testbusiness.industryMicrocirculationMagnetic resonance imagingMiddle Agedmedicine.diseasePrognosisMagnetic Resonance Imagingmedicine.anatomical_structuresymbolsmedicine.symptombusinessNuclear medicineRadiology
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Cubic boron nitride: A new prospective material for ultracold neutron application

2009

Abstract At the ultracold neutron (UCN) source of the TRIGA research reactor in Mainz, we have measured for the first time the material optical wall-potential of cubic boron nitride. The measurements were performed with a time-of-flight (TOF) spectrometer. The samples investigated had a wall-potential of ( 305 ± 15 ) neV . This value is in good agreement with the result extracted from neutron reflectometry data and theoretical expectations. Because of its high critical velocity for UCN and its good dielectric characteristics, cubic boron nitride coatings (isotopically enriched) will be useful for a number of applications in UCN experiments.

PhysicsNuclear and High Energy PhysicsSpectrometerPhysics::Instrumentation and DetectorsFOS: Physical sciencesDielectricCritical ionization velocityTRIGACondensed Matter::Materials Sciencechemistry.chemical_compoundNuclear magnetic resonancechemistryBoron nitrideNeutronResearch reactorNeutron reflectometryNuclear Experiment (nucl-ex)Atomic physicsNuclear ExperimentNuclear ExperimentInstrumentation
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Decomposition Process of Carboxylate MOF HKUST-1 Unveiled at the Atomic Scale Level

2016

HKUST-1 is a metal-organic framework (MOF) which plays a significant role both in applicative and basic fields of research, thanks to its outstanding properties of adsorption and catalysis but also because it is a reference material for the study of many general properties of MOFs. Its metallic group comprises a pair of Cu2+ ions chelated by four carboxylate bridges, forming a structure known as paddle-wheel unit, which is the heart of the material. However, previous studies have well established that the paddle-wheel is incline to hydrolysis. In fact, the prolonged exposure of the material to moisture promotes the hydrolysis of Cu-O bonds in the paddle-wheels, so breaking the crystalline n…

metal-organic-frameworks MOF electron paramagnetic resonance EPR ESR water structural stabilityInorganic chemistryFOS: Physical sciences02 engineering and technology010402 general chemistry01 natural sciencesAtomic unitslaw.inventionCatalysisMetalCrystalchemistry.chemical_compoundAdsorptionlawPhysics - Chemical PhysicsCarboxylatePhysical and Theoretical ChemistryElectron paramagnetic resonanceChemical Physics (physics.chem-ph)Condensed Matter - Materials ScienceChemistryMaterials Science (cond-mat.mtrl-sci)021001 nanoscience & nanotechnology0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsGeneral EnergyChemical engineeringvisual_artvisual_art.visual_art_mediumMetal-organic framework0210 nano-technologyThe Journal of Physical Chemistry C
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Modic changes-Their associations with low back pain and activity limitation: A systematic literature review and meta-analysis.

2018

Background Previous systematic reviews have reported positive associations between Modic changes (MCs) and low back pain (LBP), but due to their narrow scope and new primary studies, there is a need for a comprehensive systematic review. Our objectives were to investigate if MCs are associated with non-specific LBP and/or activity limitation and if such associations are modified by other factors. Methods A protocol for this review was registered at PROSPERO prior to commencing the work (PROSPERO record: CRD42015017350). The MEDLINE, CINAHL and EMBASE databases were searched for relevant studies from first record to June 15th 2016. Prospective or retrospective cross-sectional cohort studies …

Physiologylcsh:MedicinePathology and Laboratory MedicineDiagnostic RadiologyDatabase and Informatics Methods0302 clinical medicineMathematical and Statistical TechniquesBone MarrowImmune PhysiologyOdds RatioMedicine and Health SciencesIntervertebral Disc/diagnostic imagingDatabase Searchinglcsh:ScienceIntervertebral DiscMusculoskeletal System030222 orthopedicsMultidisciplinaryLumbar VertebraeRadiology and ImagingResearch AssessmentLow back painMagnetic Resonance ImagingPeer reviewSystematic reviewResearch DesignMeta-analysisSpinal Diseases/complicationsPhysical SciencesLow Back Pain/complicationsSpinal Diseasesmedicine.symptomAnatomyStatistics (Mathematics)Cohort studyResearch Articlemedicine.medical_specialtySystematic ReviewsImaging TechniquesLumbar Vertebrae/diagnostic imagingLower Back PainImmunologyPainResearch and Analysis Methods03 medical and health sciencesSigns and SymptomsDiagnostic MedicineInternal medicinemedicineHumansMobility LimitationStatistical Methodsbusiness.industrylcsh:RCase-control studyBiology and Life SciencesModic changesOdds ratioSpineCase-Control StudiesImmune Systemlcsh:QbusinessLow Back Pain030217 neurology & neurosurgeryMathematicsMeta-AnalysisPloS one
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Transcranial magnetic resonance imaging-guided focused ultrasound treatment at 1.5 T: A retrospective study on treatment- and patient-related paramet…

2020

Transcranial magnetic resonance
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AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders.

2019

AMPA receptors (AMPARs) are tetrameric ligand-gated channels made up of combinations of GluA1-4 subunits encoded by GRIA1-4 genes. GluA2 has an especially important role because, following post-transcriptional editing at the Q607 site, it renders heteromultimeric AMPARs Ca2+-impermeable, with a linear relationship between current and trans-membrane voltage. Here, we report heterozygous de novo GRIA2 mutations in 28 unrelated patients with intellectual disability (ID) and neurodevelopmental abnormalities including autism spectrum disorder (ASD), Rett syndrome-like features, and seizures or developmental epileptic encephalopathy (DEE). In functional expression studies, mutations lead to a dec…

Male[SDV.GEN] Life Sciences [q-bio]/GeneticsIon channels in the nervous systemCohort Studiesfluids and secretionsLoss of Function MutationReceptorsAMPAAMPA receptorlcsh:ScienceChildreproductive and urinary physiologyAMPA receptor GluA2 neurodevelopmental disorders autism spectrum disorder glutamatergic synaptic transmission GRIA2neurodevelopmental disordersDevelopmental disordersQNeurodevelopmental disordersBrainMagnetic Resonance ImagingSettore MED/26 - NEUROLOGIAGluA2Child PreschoolFemaleAdultHeterozygoteAdolescentScienceautism spectrum disorderArticleYoung Adult[SDV.MHEP.PED] Life Sciences [q-bio]/Human health and pathology/PediatricsMESH: Intellectual Disability/genetics; Neurodevelopmental Disorders/genetics; Receptors AMPA/genetics; HeterozygoteIntellectual Disabilitymental disordersAdolescent; Adult; Brain; Child; Child Preschool; Cohort Studies; Female; Heterozygote; Humans; Infant; Intellectual Disability; Loss of Function Mutation; Magnetic Resonance Imaging; Male; Neurodevelopmental Disorders; Receptors AMPA; Young AdultHumansReceptors AMPAGRIA2PreschoolIon channel in the nervous system Developmental disorders Synaptic development NG sequencing[SDV.GEN]Life Sciences [q-bio]/Genetics[SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatricsglutamatergic synaptic transmission[SCCO.NEUR]Cognitive science/Neuroscience[SCCO.NEUR] Cognitive science/NeuroscienceInfantNG sequencingSynaptic developmentIon channel in the nervous systemNext-generation sequencinglcsh:Q
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Dysprosium-Based Ionic Liquid Crystals: Thermal, Structural, Photo- and Magnetophysical Properties

2009

[C12mim]3[DyBr6] (C12mim = 1-dodecyl-3-methylimidazolium) represents a new material with interesting luminescent behavior as well as mesomorphic and magnetic properties. The compound was found to show thermotropic liquid crystalline behavior and forms smectic mesophases which were investigated by hot-stage polarizing optical microscopy and differential scanning calorimetry. The emission color of [C12mim]3[DyBr6] can be tuned from white to orange-yellow by the choice of the excitation wavelength. Sample excitation with λex = 366 nm leads to the blue-whitish luminescence from the imidazolium cation itself. With λex = 254 nm the common Dy(III) emission is observed which mainly arises from the …

Magnetic momentChemistryAnalytical chemistrychemistry.chemical_elementGeneral ChemistryCondensed Matter PhysicsThermotropic crystalDifferential scanning calorimetryNuclear magnetic resonanceLiquid crystalDysprosiumGeneral Materials ScienceLuminescenceExcitationSuperparamagnetismCrystal Growth & Design
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High-Yield Synthesis of 20-, 24-, and 28-Membered Macropentolide, -hexolide, and -heptolide, Respectively, from (R)- or (S)-3-hydroxybutanoic acid un…

1988

The macrocyclic pentolide 1, hexolide 2, and heptolide 3 constitute ca. 80% of the oligomers formed in ca. 50% yield from enantiomerically pure 3-hydroxybutanoic acid under Yamaguchi's macrolactonization conditions. The FAB mass spectra of the MH+, M Na+, and MCs+ are reported (Figs. 2, 3, 5, and 6). No cyclic tetramer is detected. The 1H-NMR spectra of the cyclic oligomers, of the monomer, and of the polymer (PHB) are very similar (Fig. 4). Directed synthesis of the open-chain dimer and tetramer of 3-hydroxybutanoic acid and attempted cyclization do not lead to the isolation of the cyclic tetramer.

chemistry.chemical_classificationStereochemistryDimerOrganic ChemistryNuclear magnetic resonance spectroscopyBiochemistryOligomerCatalysisInorganic Chemistrychemistry.chemical_compoundMonomerchemistryTetramerYield (chemistry)Drug DiscoveryMass spectrumPhysical and Theoretical ChemistryLactoneHelvetica Chimica Acta
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