Search results for "MALADIE"
showing 10 items of 135 documents
Theories and methods to assess the social cost of occupational risk factors in France : application to the case of occupational cancers
2011
The main objective of this thesis is to evaluate the social cost of respiratory cancer attributable to occupational risk factors in France. A summary of the available epidemiological data in the literature is performed. By using the Medline database, a review of the literature restricted to meta-analysis highlights the relative risk data available. The method of Attributable Risks (AR) is mobilized to estimate the numbers of lung, sinonasal and mesothelioma cancer cases caused by asbestos, exhaust fumes from diesel engines, painters, crystalline silica, wood dust and leather dust. We then assess the costs of these cancer cases for the french society using the Cost Of Illness (COI) method. T…
Use of hospital and amubutory data in assessment of screnning, follow-up and complications of diabetes mellitus
2017
Diabetes is a priority health target worldwide. Access to conclusive data is equally a priority in order to establish clear objectives and to implement coordinated action. Medico-administrative databases are being used more and more frequently for this purpose. We set out to illustrate and assess the interest of using a French healthcare consumption database to evaluate screening, surveillance and the risk of acute or chronic complications of diabetes in certain at-risk populations. We concluded that early screening for type-2 diabetes in women with a history of gestational diabetes was inadequate. Although a slight improvement occurred following the recommendations published in 2010, one w…
Patient/physician "Bond" in the management of glaucoma
2011
Patient/physician "Bond" in the management of glaucoma. annual meeting of the association-for-research-in-vision-and-ophthalmology (ARVO)
Study of virus flows between wild and cultivated Poaceae
2017
BGPI : équipe 6; Study of virus flows between wild and cultivated Poaceae. 16. Rencontres de Virologie Végétale (RVV 2017)
Effect of fusaric acid and phytoanticipins on growth of rhizobacteria and Fusarium oxysporum
2002
International audience
New insights into the pharmacology of the short-chain free fatty acid receptors 2 and 3
2011
Metabolic diseases, such as diabetes, dyslipidemia or obesity, are more and more weighing on public health expenses in developed countries. Despite active research, these widespread diseases remain difficult to handle. Promising new therapeutic strategies against metabolic diseases include the development of drugs targeting the free fatty acid receptors, as key players in metabolism homeostasis. In this context, the current PhD thesis focuses on the study of two G protein-coupled receptors, namely the short-chain free fatty acid receptors 2 (FFA2) and 3 (FFA3). First, we investigated the expression of the two receptors of interest in a variety of cell types. Then, in order to study the phar…
Connaissances nécessaires à la gestion du risque "écorces sensibles au nématode du pin"
2018
Connaissances nécessaires à la gestion du risque "écorces sensibles au nématode du pin"
Microglia and α-synuclein implication in Parkinson's disease
2011
Age-related neurodegenerative disorders like Parkinson’s disease take an enormous toll on individuals and on society. Despite extensive efforts, Parkinson’s disease remains incurable and only very limited treatments exist. Indeed, Parkinson’s pathogenesis is still not clear and research on its molecular mechanisms is ongoing. In this study, we focused our interest on two abnormal events occurring in Parkinson’s patients, namely α-synuclein aggregation and microglial activation. We first investigated α-synuclein and its abnormal polymerisation. For this purpose, we developed novel methods, which allowed the in vitro production of different types of α-synuclein oligomers. Using highly sensiti…
Diversity and interactions among strains of Fusarium oxysporum : application to biological control.
2001
International audience
Map gene as a new non ribosomal marker to study the molecular variability of grapevine yellows and related phytoplasmas from group 16SRV in Europe
2006
International audience