Search results for "MAM"
showing 10 items of 1679 documents
Studies on the synthesis of heterocyclic compounds. Part IX. Action ofN,N-dimethylformamide dimethylacetal on some oximino-β-dicarbonyl compounds
1982
3-Oximino-2,4-pentanedione (1) and ethyl 2-oximino-3-oxobutanoate (6) reacted with N,N-dimethylformamide dimethylacetal (DFDA) to give 1,7-bisdimethylamino-3,5-dioxo-4-methoximinohepta-1,6-diene (4) and ethyl 5-dimethylamino-2-methoximino-3-oxo-4-pentenoate (8), respectively. When compounds 4 and 8 were treated with hydrazine hydrate, they gave O-methyldipyrazol-3(5)-ylketoxime (5) and ethyl 2-methoximino-3(5)-pyrazolylethanoate (9) together with its corresponding hydrazide 10, respectively. Upon action of DFDA on 3-oximino-2,4-pentanedione (1) at -20° an explosive crystalline product was obtained. On the other hand, the reaction of 3-acetoximino-2,4-pentanedione (11) with DFDA at -20° affo…
Characterization of hOGG1 Promoter Structure, Expression During Cell Cycle and Overexpression in Mammalian Cells
2001
Oxygen radicals are produced in all cells either by the normal cellular metabolism or by the exposure to external mutagens. The reactive oxygen species (ROS) generated can induce DNA damage. Among the principal lesions found in DNA due to ROS is an oxidized form of guanine, 8-oxo-7,8-dihydroguanine (8-oxoG). The biological relevance of this lesion has been unveiled by the study of Escherichia colt and Saccharomyces cerevisiae genes involved in the neutralization of the mutagenic effects of 8-oxoG (Cabrera et al., 1988; Nghiem et al., 1988; Radicella et al., 1988; van der Kemp et al., 1996). These genes fpg and mutY for E. colt and OGG1 for yeast, code for DNA glycosylases. Inactivation of a…
Über die copolymerisation des acroleins und des methacroleins in homogener lösung. Polymere acroleine. 25. Mitt.
1962
Die Copolymerisation des Acroleins und des Methacroleins in Dimethylformamid sowie in Dioxan wird beschrieben. Die Parameter folgender Systeme wurden bestimmt: Acrolein/Acrylnitril (r1 = 1,60; r2 = 0,52); Acrolein/Acrylamid (r1 = 1,69; r2 = 0,21); Acrolein/Methacrylnitril (r1 = 0,72; r2 = 1,20); Acrolein/2-Vinylpyridin (r1 = 4; r2 = 0) und Methacrolein/Methacrylnitril (r1 = 1,78; r2 = 0,40). Die Berechnung der Q-und e-Werte bzw. der q- und ϵ-Werte ergab fur Acrolein: Q = 0,64; e = 0,61; q = -2,8 kcal/Mol; ϵ = 0,19 = 10−10 elektrostatische Einheiten und fur Methacrolein: Q = 1,59; e = 0,36; q = −3,4 kcal/Mol; ϵ = 0,11 = 10−10 elektrostatische Einheiten. The copolymerisation of acrolein and m…
Studien zum Vorgang der Wasserstoffübertragung, 41. Elektroreduktion von Acetophenon unter Mitwirkung optisch aktiver Leitsalze
1977
Die Anderung des Carbinol/Pinakol-Verhaltnisses2) (C/P) und der optischen Induktion bei der Elektroreduktion von Acetophenon mit (1 R, 2S)-N-(3-Cyanpropyl)-N-methylephedriniumbromid (1) und (1 R, 2 S)-N,N-Dimethylephedriniumbromid (2) als Leitsalze wird untersucht in Abhangigkeit: a) vom Potential (Tabelle 1), b) von der Stromdichte (Tabelle 2), c) von Pulsbedingungen (Tabelle 3), d) vom pH (Tabelle 4), e) von der Anwesenheit anderer Kationen (Tabelle 5), f) vom Losungsmittel (Tabelle 6), g) von der Temperatur (Tabelle 7) und h) von der Art des Elektrodenmaterials (Tabelle 8). — Es werden tensammetrische und cyclovoltammetrische Messungen durchgefuhrt. Die in trockenem Dimethylformamid erha…
Oxygen isotopes in mammal bone phosphate: A new tool for paleohydrological and paleoclimatological research?
1984
Abstract Oxygen isotope analyses of water in blood of humans and domestic pigs indicate that the oxygen isotope fractionation effects between ingested water and body water are the same in all specimens of the same species. The δ 18 O of body water has been shown to vary linearly with the mean δ 18 O of local meteoric water. This conclusion also holds for the bone phosphate. Thus, δ 18 O ( PO 3− 4 ) values of unaltered fossil bones from humans and domestic pigs can be used to reconstruct the δ 18 O values of local meteoric waters during the life-times of the mammals. Such data can be used for paleohydrological and paleoclimatological studies both on land and at sea.
N-(Diphenylmethylene)benzenesulfonamide andN-(Diphenylmethylene)-4-methylbenzenesulfonamide
2008
[10398-99-9] C19H15NO2S (MW 332.42) InChI = 1S/C19H15NO2S/c21-23(22,18-14-8-3-9-15-18)20-19(16-10-4-1-5-11-16)17-12-6-2-7-13-17/h1-15H InChIKey = LECLPBHPQOFADH-UHFFFAOYSA-N (reagent used as an activated imine) Physical Data: mp 119–120 °C. Form Supplied in: colorless crystals. Not commercially available. Purification: recrystalization from CH3OH. [10399-00-5] C20H17NO2S (MW 346.45) InChI = 1S/C20H17NO2S/c1-16-12-14-19(15-13-16)24(22,23)21-20(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-15H,1H3 InChIKey = ODLFJRFKAOOIKO-UHFFFAOYSA-N (reagent used as an activated imine) Physical Data: mp 103–104 °C1; 102–103 °C2; 101–102 °C5; 103 °C6; 102–104 °C.7 Solubility: soluble in pyridine, dimethylformamide, …
Perception des molécules chimiosensorielles en mélange : impact du métabolisme périphérique
2015
The chemosensory system is highly sensitive and discriminant. To ensure these properties, rapid and effective mechanisms are necessary to eliminate chemosensory molecules reaching the perception interface. The xenobiotic metabolizing enzymes (XMEs) present in the peri-receptor space may participate to the clearance of molecules thus limiting chemosensory receptors saturation and promoting the termination of the signal. In our PhD thesis, the involvement of these enzymes in the detection of stimuli in mixture was assessed in two animal models allowing to test complementary aspects. In Drosophila melanogaster, a sensory exposure to caffeine causes a reversible alteration of the taste percepti…
Alternatives to the present global development pattern : ecovillages – a model for sustainable living?
2016
Master thesis development management - University of Agder 2016 The current way of development is exhausting the planets limitations, the continues increase in consumption are degrading the nature that is relied on for human existence. Thus, it is necessary to define an alternative way of developing. The aim is to achieve happiness for all, sustaining the resources of the planet. Ecovillages are recognized as a sustainable alternative which encompasses a holistic approach to the term sustainability. Through qualitative research in the form of participatory observations, interviews and a survey performed in Gambhira, an ecovillage in rural Colombia, the sustainability, educational mission as…
Zebrafish Fins as a Model System for Skeletal Human Studies
2007
Recent studies on the morphogenesis of the fins ofDanio rerio(zebrafish) during development and regeneration suggest that a number of inductive signals involved in the process are similar to some of those that affect bone and cartilage differentiation in mammals and humans. Akimenko et al. (2002) has shown that bone morphogenetic protein-2b (BMP2b) is involved in the induction of dermal bone differentiation during fin regeneration. Many other groups have also shown that molecules from the transforming growth factor-beta superfamily (TGFβ), including BMP2, are effective in promoting chondrogenesis and osteogenesisin vivoin higher vertebrates, including humans. In the present study, we review…
Fornir los castells e vila de Murvedre. Las obras y el aprovisionamiento del castillo de Morvedre durante la guerra de Castilla (1365-1366)
2021
Los castillos eran la espina dorsal del sistema defensivo del reino de Valencia, así como de todos los estados feudales. A través del análisis de la contabilidad de un libro de obras relativo al castillo de Sagunt analizamos el papel de los castillos valencianos en la defensa del territorio y su importancia en la creación de tejido económico y en la movilización de mano de obra. El volumen es especialmente interesante porque también refleja el abastecimiento alimentario y la compra de armamento. Además, las cuentas analizadas se realizaron durante la Guerra de Castilla (1356-1375) uno de los momentos claves de la historia de la Corona de Aragón.