Search results for "MAPPING"

Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17.

2020

Background: Universal access to safe drinking water and sanitation facilities is an essential human right, recognised in the Sustainable Development Goals as crucial for preventing disease and improving human wellbeing. Comprehensive, high-resolution estimates are important to inform progress towards achieving this goal. We aimed to produce highresolution geospatial estimates of access to drinking water and sanitation facilities. Methods: We used a Bayesian geostatistical model and data from 600 sources across more than 88 low-income and middle-income countries (LMICs) to estimate access to drinking water and sanitation facilities on continuous continent-wide surfaces from 2000 to 2017, and…

Identification of proteins and developmental expression of RNAs encoded by the 65A cuticle protein gene cluster in Drosophila melanogaster

1998

0965-1748 (Print) Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.; Proteins of the third instar larval cuticle of Drosophila melanogaster, LCP5-LCP9, were purified and their N-terminal sequences determined. Three of these proteins (LCP5, 6, and 8) were found to be encoded by two multicopy genes previously mapped to the gene cluster at 65A 5-6 on the left arm of the third chromosome. The analysis of the patterns of developmental expression of the 8 distinct genes at this site showed that all but two were expressed during larval life. The patterns fell into three groups: one where expression was all through larval life, one where expression was primar…

Gene arrangement phylogeny of the E element in Drosophila species of the Obscura group

1993

Mpdz is a quantitative trait gene for drug withdrawal seizures

2004

Physiological dependence and associated withdrawal episodes can constitute a powerful motivational force that perpetuates drug use and abuse. Using robust behavioral models of drug physiological dependence in mice, positional cloning, and sequence and expression analyses, we identified an addiction-relevant quantitative trait gene, Mpdz. Our findings provide a framework to define the protein interactions and neural circuit by which this gene's product (multiple PDZ domain protein) affects drug dependence, withdrawal and relapse.

Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns.

1990

A major cytoskeletal polypeptide (Mr approximately 46,000; protein IT) of human intestinal epithelium was characterized by biochemical and immunological methods. The polypeptide, which was identified as a specific and genuine mRNA product by translation in vitro, reacted, in immunoblotting after SDS-PAGE, only with one of numerous cytokeratin (CK) antisera tested but with none of many monoclonal CK antibodies. In vitro, it formed heterotypic complexes with the type II CK 8, as shown by blot binding assays and gel electrophoresis in 4 M urea, and these complexes assembled into intermediate filaments (IFs) under appropriate conditions. A chymotrypsin-resistant Mr approximately 38,000 core fra…

Contribution of a new dynamic climate regionalization protocol for estimating the water balance of Douglas-fir forests

2022

Quantifying the regionalized impacts of climate change on forests is a major ecologicaland socio-economic issue. The decline of Douglas-fir (Pseudotsuga menziesii) has been observed forabout 20 years and should be accelered. Recent work shows that regionalized estimation of waterbalance under forest canopy is hampered by the ability of regional climate models to correctlysimulate precipitation amount and seasonal cycle. Here we evaluate the ability of a new climateregionalization protocol to simulate a realistic precipitation regime required for the calculation offorest soil water balance.

The on-line coupled atmospheric chemistry model system MECO(n) – Part 5: Expanding the Multi-Model-Driver (MMD v2.0) for 2-way data exchange includin…

2018

Abstract. As part of the Modular Earth Submodel System (MESSy), the Multi-Model-Driver (MMD v1.0) was developed to couple online the regional Consortium for Small-scale Modeling (COSMO) model into a driving model, which can be either the regional COSMO model or the global European Centre Hamburg general circulation model (ECHAM) (see Part 2 of the model documentation). The coupled system is called MECO(n), i.e., MESSy-fied ECHAM and COSMO models nested n times. In this article, which is part of the model documentation of the MECO(n) system, the second generation of MMD is introduced. MMD comprises the message-passing infrastructure required for the parallel execution (multiple programme mul…

Mapping floristic diversity: a case study in Sicily

2021

This paper presents an operational methodology to map and analyze the floristic richness of “target species” in Natura 2000 sites, making use of G.I.S. tools and procedures. A Floristic diversity map (scale 1:50,000), covering an area of 612 km2, was produced by a team of experts as part of the management plans of “Madonie Mountains” Sites of Community Importance (SCIs), located in Sicily (Italy). The primary grid map represents the richness of “target species”, which include species of Community interests, taxa on the National Red List, endemic and threatened, species protected under International Conventions, taxa of phytogeographic importance. Secondary data frames include a three-dimens…

Agricultural landscapes and biodiversity conservation: a case study in Sicily (Italy)

2015

The diversity of life is made up not only of the diversity of plants and animal species, habitats and ecosystems, but also of the diversity of human cultures. These diversities interact with one another in complex ways and express the mutual adaptation between humans and the environment at local level. Sicilian traditional agro-ecosystems, due to the history of the territory and the resulting social and economic context, are configured in a heterogeneous mosaic rich in residual features of environmental value, which enhance the connectivity of the ecological network and support a high proportion of species that are rare or of conservation concern. As a case study we analyzed the characteris…

Emotions in Economic Decision Making: A Multidisciplinary Approach

2013

AbstractAccording to classical and neoclassical economics, decisions are made based on information and cost-benefit analysis. In reality, the decision making process is much more complex than previously thought, because it also involves psychological factors. Decision making is interdisciplinary, researched by psychologists, sociologists, economists, philosophers, neuroscientists and others. These fields have distinctive and common concepts about decision making. The aim of this paper is to identify what role emotions play in the economic decision making process. The paper focuses on describing and explaining the interconnection of sciences, such as economics, psychology and neuroscience, b…