Search results for "MD"
showing 10 items of 977 documents
Two Teletraffic-based Schemes for Energy Saving in Cellular Networks with Micro-cells
2012
Published version of an article in the journal: Journal of Communications. Also available from the publisher at: http://dx.doi.org/10.4304/jcm.7.10.726-739 Open access The energy consumption of Base Stations (BSs) is known to constitute a major part of the power consumption in a cellular network. In this paper, we propose a novel approach which may switch a BS off under light traffic conditions in order to conserve the power consumption of such networks. More specifically, when the traffic load in the middle cell of a network with three micro-cells is sufficiently low, the corresponding BS can be switched off and its users will be covered by increasing the transmission power of one sector a…
Direct interaction of the Usher syndrome 1G protein SANS and myomegalin in the retina
2011
Contains fulltext : 96822.pdf (Publisher’s version ) (Closed access) The human Usher syndrome (USH) is the most frequent cause of combined hereditary deaf-blindness. USH is genetically heterogeneous with at least 11 chromosomal loci assigned to 3 clinical types, USH1-3. We have previously demonstrated that all USH1 and 2 proteins in the eye and the inner ear are organized into protein networks by scaffold proteins. This has contributed essentially to our current understanding of the function of USH proteins and explains why defects in proteins of different families cause very similar phenotypes. We have previously shown that the USH1G protein SANS (scaffold protein containing ankyrin repeat…
Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder
2010
Contains fulltext : 87688.pdf (Publisher’s version ) (Closed access) OBJECTIVE: Although twin and family studies have shown attention-deficit/hyperactivity disorder (ADHD) to be highly heritable, genetic variants influencing the trait at a genome-wide significant level have yet to be identified. As prior genome-wide association studies (GWAS) have not yielded significant results, we conducted a meta-analysis of existing studies to boost statistical power. METHOD: We used data from four projects: a) the Children's Hospital of Philadelphia (CHOP); b) phase I of the International Multicenter ADHD Genetics project (IMAGE); c) phase II of IMAGE (IMAGE II); and d) the Pfizer-funded study from the…
Vaccinum ģints ogu ekstraktu pretvēža aktivitātes pētīšana krūts vēža šūnu līnijās
2018
Mūsdienās ar vien vairāk tiek meklēti jauni pretvēža līdzekļi, izmantojot augu valsts produktus. Maģistra darba mērķis bija noskaidrot, vai Vaccinium ģints ogu ekstrakti dažādās koncentrācijās ietekmē primārā krūts vēža MCF-7, metastātiskā krūts vēža MDA-MB-231 šūnas un ādas mezenhimālo cilmes šūnu D6 dzīvotspēju. Pētījumā tika izmantoti pieci ogu ekstrakti – mellene, krūmmellene, lielogu dzērvene, purva dzērvene un brūklene. Šūnām pievienoja ekstraktus koncentrācijās no 0,0016 mg/ml līdz 1 mg/ml un ar kolorimetrisku metodi (CCK-8) un mikroskopiju noteica šūnu dzīvotspēju un IC50. Visvairāk tiek samazināta MDA-MB-231 šūnu dzīvotspēja, salīdzinot ar MCF-7 un D6 šūnām. Visvairāk krūts audzēja…
Colonizzazione da batteri Gram negativi multi-resistenti in pazienti pediatrici
2017
INTRODUZIONE: La diffusione della resistenza batterica in ospedale e in comunità costituisce un serio motivo di allarme anche nella popolazione pediatrica. Recenti studi hanno dimostrato come le infezioni sostenute da batteri gram-negativi multiresistenti (MDRGN) oggi si presentino sempre più frequentemente anche in comunità, e come più del 15% dei bambini siano colonizzati da MDRGN al momento del ricovero in ospedale. L’introduzione di questi microrganismi in comunità rappresenta un serio fattore di rischio per lo sviluppo di infezioni difficilmente trattabili. Il nostro studio ha indagato la presenza di batteri MDRGN nella popolazione microbica intestinale di bambini ricoverati con sintom…
In vitro evaluation of the antibacterial activity of cured dentin/enamel adhesive incorporating the antimicrobial agent MDPB
2010
The aim of this study was to investigate in vitro the antibacterial effect of a dentin/enamel adhesive containing MDPB (Clearfil Protect Bond) after curing and to compare it with an adhesive not containing MDPB (Clearfil SE Bond). The antibacterial effect of the cured adhesives was tested on Enterococcus faecalis by the evaluation of growth inhibition in a 48-h microplate direct contact test (DCT). The presence of antibacterial activity due to soluble components was also investigated by an agar diffusion test (ADT) performed with the adhesives cured on the surface of dentin disks. In the DCT, both the tested materials showed complete inhibition of bacterial growth until the 7-h reading, reg…
Response to computer-assisted intervention in children most at risk for mathematics difficulties
2015
Evidence of an association between poor early number skills and a high risk for later difficulties in mathematics manifests a need for both early identification of risk and effective prevention of difficulties. However, only a few theory-based assessment and progress monitoring tools, and intervention methods are avail able for this purpose in Finnish pre-primary education. This thesis aimed to examine to what extent a theory-based computer-assisted intervention method (GraphoGame Math, GGM) can support early number skills development in children (67-year-olds) most at risk for mathematics difficulties (MD; defined as performance below the 10th percentile). The specific aims were threefold…
Dzemdes kakla vēža pacientu pozicionēšanas iespējas un precizitāte staru terapijā
2019
Bakalaura darba mērķis ir izvērtēt un salīdzināt imobilizācijas iekārtu: ceļu un pēdu paliktņa un vakuumaisa precizitāti dzemdes kakla vēža pacientiem distances staru terapijā. Pacientēm ar dzemdes kakla vēža diagnozi lielu nozīmi distances staru terapijā dod līdzestība. Darba teorētiskajā daļā autors apraksta sieviešu dzimumorgānu anatomiju, fizioloģiju, veic teorētisku izklāstījumu par to, kas ir dzemdes kakla vēzis, kādi ir rašanās cēloņi un diagnostika. Darbā tiek aprakstītas distances staru terapijas ārstēšanas iespējas pacientēm ar dzemdes kakla vēža diagnozi. Teorētiskās daļas nobeigumā autors apraksta imobilizācijas iespējas un to funkcionalitāti distances staru terapijā. Pētniecība…
Genetic Factors as Promising Biomarkers of Sporadic Ascending Aortic Aneurysm
2014
Thoracic aorta shows various changes with advancing age and a progressive deterioration in structure and function. As a result, vascular remodeling (VR) and medial degeneration (MD) occur. VR and MD are typical entities of sporadic thoracic aortic aneurysm (TAA), actually considered a common and serious health risk and a pathology by unclear mechanisms. Increased activity of the coagulation system, inflammation, activation of extracellular matrix remodeling and endothelial dysfunction pathways have been recently evidenced to have a key role in its onset. Thus, polymorphisms of the coagulation system [fibrinogen (rs1800790); Factor II ( rs1799963); Factor V (rs6025); Factor VII (rs121964926)…
TEMPORAL STRUCTURE OF THE MUSCULAR DYSTROPHY X-LINKED MOUSE BEHAVIOUR TESTED IN OPEN FIELD
2017
In comparison with wilde type mice, animal models of Duchenne Muscolar Dystrophy (mdx mice) show a different behavioral organization with a more articulated structure of the temporal patterns. Present study sheds light, for the first time, on specific temporal features of behavior in an animal model of DMD.