Search results for "MEA"

showing 10 items of 8532 documents

Long-term effects of a cluster randomized controlled kindergarten-based intervention trial on vegetable intake among Norwegian 3-5-year-olds: the BRA…

2020

AbstractObjectiveTo report on long-term effects of a cluster randomized controlled kindergarten-based intervention trial, which aimed to increase vegetable intake among Norwegian preschool children (3–5 years at baseline). The effects of the intervention at follow-up 1 (immediately post-intervention) have previously been published. This paper presents the effects of the intervention from baseline to follow-up 2 (12 months post-intervention).ResultsParental consents were obtained for 633 out of 1631 eligible children (response rate 38.8%). The effects of the intervention from baseline to follow-up 2 were assessed by mixed-model analyses taking the clustering effect of kindergartens into acco…

0301 basic medicineMaleParentslcsh:MedicineNorwegianDisease clusterGeneral Biochemistry Genetics and Molecular BiologyMean differencelaw.inventionVDP::Medisinske Fag: 700::Helsefag: 800::Ernæring: 81103 medical and health sciencesEating0302 clinical medicineRandomized controlled triallawSurveys and QuestionnairesVegetablesMedicineHumans030212 general & internal medicineIntervention triallcsh:Science (General)Trial registrationChildlcsh:QH301-705.5Response rate (survey)030109 nutrition & dieteticsSchoolsbusiness.industryNorwaylcsh:RPreschool childrenGeneral MedicineFeeding Behaviorlanguage.human_languageResearch Notelcsh:Biology (General)Child PreschoolFruitlanguageLong-term intervention effectFemaleKindergarten-based interventionbusinessRCTlcsh:Q1-390DemographyFollow-Up StudiesBMC research notes
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Diagnostic accuracy of cerebrospinal fluid biomarkers measured by chemiluminescent enzyme immunoassay for Alzheimer disease diagnosis.

2020

In the last decades, an important role of cerebrospinal fluid (CSF) biomarkers for Alzheimer disease (AD) diagnosis has emerged. The evaluation of the triad consisting of 42 aminoacid-long amyloid-beta peptide (Aβ42), total Tau (tTau) and Tau phosphorylated at threonine 181 (pTau) have been recently integrated into the research diagnostic criteria of AD. For a long time, the enzyme-linked immunosorbent assay (ELISA) has represented the most commonly used method for the measurement of CSF biomarkers levels. This study aimed to assess the diagnostic accuracy of CSF biomarkers, namely Aβ42, tTau and pTau and their ratio, measured by fully automated CLEIA assay (Lumipulse). We included 96 patie…

0301 basic medicineMalePathologymedicine.medical_specialtyAmyloidClinical Biochemistrychemiluminescent enzyme immunoassay methodCSF biomarkerDiagnostic accuracyEnzyme-Linked Immunosorbent Assaytau Proteinslaw.invention03 medical and health sciences0302 clinical medicineCerebrospinal fluidliquorlawAlzheimer DiseasemedicineHumansPhosphorylationChemiluminescenceAgedchemistry.chemical_classificationAutomation LaboratoryAmyloid beta-Peptidesmedicine.diagnostic_testbusiness.industryGeneral MedicineCLEIAMiddle Agedmedicine.diseasePeptide Fragments030104 developmental biologyEnzymechemistryROC CurveImmunoassayArea Under CurveCase-Control StudiesCsf biomarkersLuminescent MeasurementsFemaleAlzheimer's diseasebusiness030217 neurology & neurosurgeryBiomarkersScandinavian journal of clinical and laboratory investigation
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Self-Reported Non-Celiac Wheat Sensitivity in High School Students: Demographic and Clinical Characteristics

2017

Background: Non-Celiac Wheat Sensitivity (NCWS) has recently been included among the gluten-related disorders. As no biomarkers of this disease exist, its frequency has been estimated based on self-reported symptoms, but to date no data are available about self-reported NCWS in teenagers. Aim: To explore the prevalence of self-reported NCWS in a group of high school students and to study their demographic and clinical characteristics. Methods: The study was performed between April 2015 and January 2016 in two high schools of a coastal town in the south of Sicily (Italy). A total of 555 students (mean age 17 years, 191 male, 364 female) completed a modified validated questionnaire for self-r…

0301 basic medicineMalePediatricsSettore MED/09 - Medicina InternaDiseaseWheat HypersensitivityEpidemiologyEstablished diagnosisSicilyTriticumNon-Celiac Wheat Sensitivityeducation.field_of_studyNutrition and DieteticsteenagersValidated questionnaireSelf-Reported; Non-Celiac Wheat Sensitivity; High School Students; Demographic Characteristics; Clinical Characteristicsself-reported non-celiac wheat sensitivity; non-celiac gluten-sensitivity; epidemiology; prevalence; teenagers; IBS; food allergyFemaleepidemiologyNon-celiac gluten sensitivitylcsh:Nutrition. Foods and food supplymedicine.medical_specialtyAdolescentGlutensPopulationprevalencelcsh:TX341-641Article03 medical and health sciencesDiet Gluten-FreeIBSmedicineHumanseducationStudentsDemographic CharacteristicHigh School Studentfood allergy030109 nutrition & dieteticsbusiness.industryMean agemedicine.diseaseCeliac DiseaseCase-Control StudiesSelf-ReportedSelf Reportbusinessnon-celiac gluten-sensitivityClinical CharacteristicsFood Scienceself-reported non-celiac wheat sensitivityNutrients; Volume 9; Issue 7; Pages: 771
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Effect of three edible oils on the intestinal absorption of caffeic acid: An in vivo and in vitro study.

2016

Polyphenolic antioxidants are mainly absorbed through passive paracellular permeation regulated by tight junctions. Some fatty acids are known to modulate tight junctions. Fatty acids resulting from the digestion of edible oils may improve the absorption of polyphenolic antioxidants. Therefore, we explored the effect of three edible oils on the intestinal absorption of caffeic acid. Rats were fed with soybean oil and caffeic acid dissolved in distilled water. Caffeic acid contents in the plasma collected up to 1 hr were quantified. The experiment was repeated with coconut oil and olive oil. Component fatty acids of the oils were individually tested in vitro for their effect on permeability …

0301 basic medicineMalePhysiologyMyristic acidlcsh:MedicineBiochemistryIntestinal absorptionSoybean oilAntioxidantschemistry.chemical_compoundPlant ProductsCaffeic acidMedicine and Health SciencesFood sciencelcsh:ScienceMultidisciplinaryCoconut oilFatty Acidsfood and beveragesAgriculture04 agricultural and veterinary sciences040401 food scienceLipidsBody FluidsBloodBiochemistryPhysical SciencesCoconut OilJunctional ComplexesAnatomyResearch ArticleCell Physiologyfood.ingredientLinoleic acidMaterials ScienceMaterial PropertiesBiological Transport ActiveCropsVegetable OilsBlood PlasmaPermeabilityTight Junctions03 medical and health sciences0404 agricultural biotechnologyfoodCaffeic AcidsAnimalsHumansPlant OilsRats Wistar030109 nutrition & dieteticslcsh:RBiology and Life SciencesCell BiologyLauric acidAgronomyRatsSoybean OilOleic acidchemistryIntestinal Absorptionlcsh:QCaco-2 CellsSoybeanOilsCrop SciencePloS one
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Case-based surveillance of measles in Sicily during 2012-2017: The changing molecular epidemiology and implications for vaccine strategies.

2018

Following the indication of the World Health Organization, a national plan for the elimination of measles was approved in Italy and this included the improvement of the molecular surveil- lance of measles viruses and the interruption of indigenous transmission of the disease. Nevertheless, large outbreaks continue to occur in almost all regions of the country, includ- ing Sicily. Here we describe the epidemiology and molecular dynamics of measles viruses as a result of the measles surveillance activity carried out by the “Reference Laboratory for Measles and Rubella” in Sicily over a 5-year period. Biological samples of 259 suspected measles cases were tested for viral RNA detection and a t…

0301 basic medicineMaleRNA virusesViral DiseasesHeredityMeasles Surveillance Vaccine Epidemiology Molecular epidemiology Genotyping Sicily Italylcsh:MedicineSettore MED/42 - Igiene Generale E ApplicataPathology and Laboratory MedicineGeographical locationsEpidemiologyMedicine and Health SciencesPublic and Occupational HealthChildlcsh:ScienceSicilyData ManagementMolecular EpidemiologyMultidisciplinarybiologyTransmission (medicine)Database and informatics methodsSequence analysisPhylogenetic AnalysisVaccination and ImmunizationPhylogeneticsEuropeGenetic MappingInfectious DiseasesItalyMedical MicrobiologyChild PreschoolViral PathogensVirusesRNA ViralPathogensResearch ArticleAdultmedicine.medical_specialtyComputer and Information SciencesAdolescentBioinformaticsMeasles VaccineImmunologyNucleotide SequencingMeasles VirusVariant GenotypesRubellaMeaslesMicrobiologyMeasles virus03 medical and health sciencesYoung AdultmedicineGeneticsHumansEvolutionary SystematicsEuropean UnionMolecular Biology TechniquesSequencing TechniquesGenotypingMicrobial PathogensMolecular BiologyDNA sequence analysisRetrospective StudiesTaxonomyEvolutionary BiologyMolecular epidemiologyBiology and life scienceslcsh:ROrganismsOutbreakInfantbiology.organism_classificationmedicine.diseaseVirologyResearch and analysis methods030104 developmental biologyParamyxoviruseslcsh:QPreventive MedicinePeople and placesMeaslesPLoS ONE
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Facial cutaneo-mucosal venous malformations can develop independently of mutation of TEK gene but may be associated with excessive expression of Src…

2017

International audience; We aimed to search for mutations in the germline and somatic DNA of the TEK gene and to analyze the expression level of Src and phospho- Src (p-Src) in tumor and healthy tissues from patients with facial cutaneo-mucosal venous malformations (VMCM). Eligible patients from twelve families and thirty healthy controls were recruited respectively at the Departments of Stomatology and Oral Surgery, and Transfusion Medicine of Tlemcen University Medical Centre. Immunoblot analyses of Src and p-Src were performed after direct DNA sequencing. No somatic or germline mutations were found in all the 23 exons and their 5' and 3' intronic flanking regions, except for one case in w…

0301 basic medicineMaleSomatic cellVascular MalformationsCutaneo-mucosal venous malformationsTyrosine Kinase Tie2Bioinformaticsmedicine.disease_causeGermlineMetastasisp-SrcExonPharmacology Toxicology and Pharmaceutics(all)General Pharmacology Toxicology and PharmaceuticsPhosphorylationCancerMedicine(all)MutationBrief ReportGeneral MedicineReceptor TIE-2[SDV.BDD.MOR] Life Sciences [q-bio]/Development Biology/Morphogenesis3. Good healthsrc-Family Kinases[SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]FemaleProto-oncogene tyrosine-protein kinase SrcReceptorSrc[SDV.MHEP.AHA] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]AdolescentDirect sequencingContext (language use)BiologyVegfGeneral Biochemistry Genetics and Molecular BiologyPermeability03 medical and health sciencesGermline mutationTEK gene[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN][ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologymedicine[SDV.MHEP.AHA]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]HumansAmino Acid SequenceGeneMucous MembraneCell-Lines[ SDV ] Life Sciences [q-bio]Base SequenceBiochemistry Genetics and Molecular Biology(all)[SDV.BDD.MOR]Life Sciences [q-bio]/Development Biology/MorphogenesisGermline and somatic DNA030104 developmental biologyFaceMutationCancer researchSkin AbnormalitiesAngiogenesisPathwayJournal of negative results in biomedicine
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Possible effects of a free, healthy school meal on overall meal frequency among 10–12-year-olds in Norway: the School Meal Project

2018

Abstract Objective To evaluate possible effects of intake of a free, healthy school meal on overall meal frequency among 10–12-year-olds in Norway. This was evaluated using a quasi-experimental school-based intervention study assessing children’s meal frequency retrospectively using a questionnaire in two elementary schools in the southern part of Norway in 2014/15. Multiple logistic regression analyses with breakfast, lunch, dinner, supper as dependent variables were used. Results A total of 164 children at baseline; 55 children in the intervention group and 109 children in the control group were included. The serving of a free school meal every day for 1 year did not improve the overall m…

0301 basic medicineMaleSupperFree school meallcsh:MedicineInterventionLogistic regressionGeneral Biochemistry Genetics and Molecular BiologyOddsVDP::Medisinske Fag: 700::Helsefag: 800::Ernæring: 81103 medical and health sciences0302 clinical medicineSurveys and QuestionnairesMedicineHumansFree school meal030212 general & internal medicineChildlcsh:Science (General)MealsChildrenlcsh:QH301-705.5Retrospective StudiesMeal030109 nutrition & dieteticsSchoolsbusiness.industryNorwaydigestive oral and skin physiologylcsh:RFood ServicesGeneral MedicineOdds ratioSchool mealConfidence intervalMeal frequencyResearch NoteLogistic ModelsLunchSocioeconomic Factorslcsh:Biology (General)FemalebusinessEnergy IntakeDemographylcsh:Q1-390BMC Research Notes
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Dietary Diversity and Nutritional Adequacy among an Older Spanish Population with Metabolic Syndrome in the PREDIMED-Plus Study: A Cross-Sectional An…

2019

Dietary guidelines emphasize the importance of a varied diet to provide an adequate nutrient intake. However, an older age is often associated with consumption of monotonous diets that can be nutritionally inadequate, increasing the risk for the development or progression of diet-related chronic diseases, such as metabolic syndrome (MetS). To assess the association between dietary diversity (DD) and nutrient intake adequacy and to identify demographic variables associated with DD, we cross-sectionally analyzed baseline data from the PREDIMED-Plus trial: 6587 Spanish adults aged 55&ndash

0301 basic medicineMaleSíndrome metabòlicamodelos logísticosCross-sectional studydietary diversityhumanosOverweightRecommended Dietary AllowancesFood groupencuestas sobre dietas0302 clinical medicineMedicinemediana edad2. Zero hungereducation.field_of_studyancianoNutrition and DieteticsdietaPREDIMED-Plus studyMiddle Aged3. Good healthestado nutricionalnutritionQuartileAvaluació de l'estat nutricionalDietary Reference IntakeDietaFemalemedicine.symptomNutritional status measurementcantidad dietética recomendadalcsh:Nutrition. Foods and food supplynutrient adequacyPopulationNutritional Status030209 endocrinology & metabolismlcsh:TX341-641Diet SurveysArticlemetabolic syndrome03 medical and health sciencesPremides-plus studyEnvironmental healthPREDIMED-Plus study aging dietary diversity metabolic syndrome nutrient adequacyHumansObesityanálisis multifactorialeducationobesidadAged030109 nutrition & dieteticsbusiness.industryagingOdds ratiomedicine.diseaseObesityDietCross-Sectional StudiesLogistic ModelsMultivariate AnalysisbusinessFood Scienceestudios transversales
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Clinical Determinants of Thrombin Generation Measured in Presence and Absence of Platelets-Results from the Gutenberg Health Study.

2018

AbstractThe tendency of a plasma sample to generate thrombin, a central enzyme in blood coagulation, might be an important indicator of prothrombotic risk linked to cardiovascular disease (CVD), but the presence of platelets may be a critical determinant. Clinical data, laboratory markers and thrombin generation (TG), investigated in both platelet-rich plasma (PRP) and platelet-free plasma (PFP) at 1 pM TF, were available in 407 individuals from the Gutenberg Health Study. Given the well-known effect of anticoagulants on TG, subjects taking anticoagulants (n = 15) have been excluded resulting in 392 subjects for further analysis. Lag time, endogenous thrombin potential (ETP) and peak height…

0301 basic medicineMaleTime Factorspopulation030204 cardiovascular system & hematologyFibrinogenDISEASEHYPERCOAGULABILITYACTIVATION0302 clinical medicineRisk FactorsGermanyMedicinePlateletProspective StudiesBLOOD-COAGULATIONBlood coagulation testeducation.field_of_studybiologyPlatelet-Rich PlasmaMICROPARTICLESThrombinHematologyclinical epidemiologyMiddle AgedDEFICIENCYC-Reactive ProteinCoagulationCardiovascular Diseasesthrombin generationplateletsFemaleBlood Coagulation TestsMean Platelet Volumemedicine.drugAdultBlood Plateletsmedicine.medical_specialtyPopulationRisk AssessmentMECHANISMS03 medical and health sciencesThrombinINFLAMMATIONPredictive Value of TestsInternal medicineHumansMean platelet volumeeducationBlood CoagulationAgedVENOUS THROMBOEMBOLISMbusiness.industryPlatelet CountC-reactive proteinATHEROTHROMBOSIS030104 developmental biologyEndocrinologybiology.proteinbusinessThrombosis and haemostasis
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Family meal participation is associated with dietary intake among 12-month-olds in Southern Norway

2021

Abstract Background Family meal participation is associated with healthier eating among children and adolescents. Less is known about family meal participation among infants and toddlers. The objective of the present study was to explore whether family meal participation at 12 months of age is associated with dietary intake and whether a potential relationship differs according to maternal education or child sex. Methods Follow-up data from children born to mothers participating in the Norwegian Fit for Delivery (NFFD) trial during pregnancy were used to assess the frequency of intake of 11 dietary items according to frequency of participating in the respective family meals. Dietary differe…

0301 basic medicineMaleToddlerFamily mealsAdolescentContext (language use)NorwegianIntervention groupVDP::Medisinske Fag: 700::Helsefag: 800::Ernæring: 81103 medical and health sciencesEating0302 clinical medicineVegetablesMedicineDrinking waterHumans030212 general & internal medicineToddlerMealsMealPregnancy030109 nutrition & dieteticsbusiness.industryNorwayDietary intakeCommercial baby cerealdigestive oral and skin physiologylcsh:RJ1-570Infantlcsh:PediatricsFeeding BehaviorSweetened beveragesmedicine.diseaselanguage.human_languagePeer reviewDietCross-Sectional StudiesPediatrics Perinatology and Child HealthlanguagebusinessDiet qualityDemographyResearch ArticleBMC Pediatrics
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