Search results for "MEA"

showing 10 items of 8532 documents

How the Context Matters. Literal and Figurative Meaning in the Embodied Language Paradigm

2014

The involvement of the sensorimotor system in language understanding has been widely demonstrated. However, the role of context in these studies has only recently started to be addressed. Though words are bearers of a semantic potential, meaning is the product of a pragmatic process. It needs to be situated in a context to be disambiguated. The aim of this study was to test the hypothesis that embodied simulation occurring during linguistic processing is contextually modulated to the extent that the same sentence, depending on the context of utterance, leads to the activation of different effector-specific brain motor areas. In order to test this hypothesis, we asked subjects to give a moto…

AdultDeep linguistic processinglcsh:MedicineSocial SciencesContext (language use)Literal and figurative languageEmbodied Language ParadigmSentence processingYoung AdultNeurolinguisticsPsychologyHumanslcsh:Scienceidioms.Settore M-FIL/05 - Filosofia E Teoria Dei LinguaggiLanguageMultidisciplinarymotor simjulationFootlcsh:RContextCognitive PsychologyBiology and Life SciencesHandPhilosophyMetaphorCognitive Sciencelcsh:QPsychologyPsychomotor PerformanceUtteranceSentenceResearch ArticleNeuroscienceMeaning (linguistics)Cognitive psychologyPLoS ONE
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First-trimester screening for trisomy-21 using a simplified method to assess the presence or absence of the fetal nasal bone.

2005

Objective To determine the benefit of including nasal bone assessment in addition to standard first-trimester markers (nuchal translucency, free beta human chorionic gonadotropin and pregnancy-associated plasma protein A) as a screening test for Down syndrome, using a strict criterion for classification of nasal bone absence. Study design Nasal bone assessment was conducted in 2411 patients with crown-rump length between 45 and 84 mm, including 15 patients with Down syndrome. A patient was considered to have an absent nasal bone only if there was no evidence of present nasal bone. Unlike other studies, nasal bone was classified as present when there was evidence of a thin echogenic line und…

AdultDown syndromemedicine.medical_specialtyPregnancy-associated plasma protein AUrologyAneuploidyPrenatal diagnosisEmbryonic StructuresSensitivity and SpecificityCrown-Rump LengthUltrasonography PrenatalPredictive Value of TestsPregnancyReference ValuesRisk FactorsmedicineConfidence IntervalsHumansMass ScreeningNasal BoneProbabilityObstetricsbusiness.industryObstetrics and GynecologyEchogenicityPrenatal Caremedicine.diseaseNasal boneConfidence intervalPregnancy Trimester FirstCase-Control StudiesLinear ModelsFemaleDown SyndromeTrisomybusinessNuchal Translucency MeasurementAmerican journal of obstetrics and gynecology
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Higher leukocyte subpopulation counts in healthy smoker industrial workers than in nonsmoker industrial workers: possible health consequences.

2012

<b><i>Objectives:</i></b> Cigarette smoke contains free radicals, which cause injury to endothelial cells and oxidize bioactive components in the blood. Neutrophils, a subpopulation of leukocytes, contain the enzyme myeloperoxidase that mediates production of hypochlorous acid during oxidative stress. In this study, we investigated whether smoker industrial workers had significantly higher neutrophil counts than nonsmoker industrial workers. <b><i>Design and Methods:</i></b> We collected blood samples from 183 apparently healthy male and 30 female industrial workers. We obtained blood cell counts, measured the concentration of plasma aminothio…

AdultErythrocyte IndicesMaleErythrocytesCause injuryNeutrophilsPhysiologyHealthy smokerHemoglobinsLeukocyte CountFolic AcidmedicineLeukocytesCigarette smokeHumansIndustryLymphocytesMean corpuscular volumeOccupational Healthmedicine.diagnostic_testHealth consequencesbusiness.industrySmokingHematologyGeneral MedicineMiddle AgedBasophilsEosinophilsVitamin B 12ImmunologyFemalebusinessActa haematologica
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Carbohydrate-deficient transferrin (CDT) and HDL cholesterol (HDL) are highly correlated in male alcohol dependent patients.

2000

Background: Serum levels of total HDL cholesterol (HDL) are reportedly influenced by recent alcohol intake. We examined the correlation between HDL cholesterol and widely used markers of excessive alcohol intake, such as carbohydrate-deficient transferrin (CDT), γ-glutamyl-transferase (GGT), or mean corpuscular volume of erythrocytes (MCV), of which CDT is thought to be the most specific. Methods: Several serological markers [i.e., CDT, GGT, aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT), MCV, and HDL] were determined in 100 actively drinking male patients with alcohol dependence (DSM-IV) and in 27 non-alcohol-dependent controls, according to routine procedures. Spearman…

AdultErythrocyte IndicesMalemedicine.medical_specialtyAdolescentCarbohydrate deficient transferrinMedicine (miscellaneous)AlcoholToxicologyStatistics Nonparametricchemistry.chemical_compoundInternal medicinemedicineHumansMean corpuscular volumeAgedchemistry.chemical_classificationEthanolmedicine.diagnostic_testbusiness.industryCholesterolAlcohol dependenceCholesterol HDLTransferringamma-GlutamyltransferaseMiddle AgedPsychiatry and Mental healthAlcoholismEndocrinologychemistryTransferrinToxicitylipids (amino acids peptides and proteins)businessBiomarkersAlcoholism, clinical and experimental research
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Exercise Effects on Erythrocyte Deformability in Exercise-induced Arterial Hypoxemia

2014

Exercise-induced arterial hypoxemia (EIAH) is often found in endurance-trained subjects at high exercise intensity. The role of erythrocyte deformability (ED) in EIAH has been scarcely explored. We aimed to explore the role of erythrocyte properties and lactate accumulation in the response of ED in EIAH. ED was determined in 10 sedentary and in 16 trained subjects, both before and after a maximal incremental test, and after recovery, along with mean corpuscular volume (MCV) and red blood cell lactate concentrations. EIAH was found in 6 trained subjects (∆SaO2=-8.25±4.03%). Sedentary and non-EIAH trained subjects showed reduced ED after exercise, while no effect on ED was found in EIAH train…

AdultErythrocyte IndicesMalemedicine.medical_specialtyErythrocytesCell volumeArterial hypoxemiaPhysical Therapy Sports Therapy and RehabilitationErythrocyte DeformabilityInternal medicinemedicineHumansErythrocyte deformabilityOrthopedics and Sports MedicineLactic AcidExercise physiologyHypoxiaExerciseMean corpuscular volumemedicine.diagnostic_testbusiness.industryIncremental testOxygenHemoglobinometryExercise intensityCardiologyPhysical therapybusinessPerfusionInternational Journal of Sports Medicine
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α-Thalassemia Does Not Seem to Influence Erythrocyte Deformability in Sickle Cell Trait Carriers

2014

Studies dealing with rheological red blood cell (RBC) behavior in sickle cell trait carriers are scarce. Moreover, the association with α-thalassemia (α-thal), which also modifies erythrocyte behavior, has not always been taken into account. We analyzed erythrocyte deformability by means of a shear stress diffractometer, along with hematological and biochemical parameters (glucose and plasma lipids), given their possible influence on erythrocyte deformability, in 14 sickle cell trait carriers and 23 healthy controls. Nine patients were also α-thal carriers and five were not. Among the thalassemia carriers, eight were heterozygous and one was homozygous. When compared with controls, sickle c…

AdultErythrocyte IndicesMalemedicine.medical_specialtyErythrocytesThalassemiaHemoglobin SickleClinical BiochemistryMutation MissenseSickle Cell Traitalpha-ThalassemiaErythrocyte DeformabilityInternal medicinePlasma lipidsmedicineHumansErythrocyte deformabilityMean corpuscular volumeGenetics (clinical)Sickle cell traitmedicine.diagnostic_testbusiness.industryBiochemistry (medical)HematologyMiddle Agedmedicine.diseaseRed blood cellHemoglobinopathymedicine.anatomical_structureEndocrinologyAmino Acid SubstitutionImmunologyFemaleHemoglobinbusinessHemoglobin
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Effects of ethanol and acetaldehyde on phagocytic functions

1985

Although a number of skin diseases are characterized by the presence of an increased number of phagocytes in their lesions, the effects of alcohol on phagocytic functions are not clearly understood. Therefore, we measured the influence of ethanol and acetaldehyde on the generation of oxygen radicals, chemotaxis and the release of lysosomal enzymes from human phagocytes. We added 0.03%-3% ethanol and 0.005%-0.25% acetaldehyde to cell cultures. We found that both ethanol and acetaldehyde suppressed the generation of oxygen radicals from granulocytes and monocytes; the ID50 was achieved at concentrations of approximately 0.25% for ethanol and 0.03% for acetaldehyde. A significant inhibition of…

AdultEthanolAdolescentEthanolNeutrophilsAcetaldehydeAlcoholAcetaldehydeDermatologyGeneral MedicineMonocytesRespiratory burstChemotaxis LeukocyteKineticschemistry.chemical_compoundPhagocytosischemistryBiochemistryLactate dehydrogenaseLuminescent MeasurementsHumansLymphocytesGranulocyte chemotaxisLysozymeEthanol metabolismArchives of Dermatological Research
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The Effectiveness Of Radial Extracorporeal Shock Wave Therapy In Patients With Chronic Low Back Pain: A Prospective, Randomized, Single-Blinded Pilot…

2019

Karolina Walewicz,1 Jakub Taradaj,2,3 Katarzyna Rajfur,1 Kuba Ptaszkowski,4 Michał Tomasz Kuszewski,2 Mirosław Sopel,5 Robert Dymarek5 1Faculty of Physiotherapy, Opole Medical School, Opole, Poland; 2Institute of Physiotherapy and Health Sciences, Academy of Physical Education, Katowice, Poland; 3College of Rehabilitation Sciences, University of Manitoba, Winnipeg, MB, Canada; 4Department of Physiotherapy, Wroclaw Medical University, Wroclaw, Poland; 5Department of Nervous System Diseases, Wroclaw Medical University, Wroclaw, PolandCorrespondence: Robert DymarekDepartment of Nervous System Diseases, Faculty of Health Sciences, Wroclaw Medical University, Bartla 5, Wroclaw 51-618, PolandTe…

AdultExtracorporeal Shockwave TherapyMaleExtracorporeal shock wave therapyVisual analogue scalePilot Projects03 medical and health sciences0302 clinical medicineHumansPain ManagementMedicinephysical therapySingle-Blind MethodIn patientProspective Studies030212 general & internal medicineOriginal ResearchPain Measurementfunctional statebusiness.industryESWTshock wavesGeneral MedicinePain scaleMiddle AgedLow back painChronic low back painOswestry Disability IndexTreatment OutcomeAnesthesiaClinical Interventions in AgingHomogeneous groupFemaleGeriatrics and Gerontologymedicine.symptombusinessLow Back Pain030217 neurology & neurosurgeryClinical Interventions in Aging
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A finite element-based machine learning approach for modeling the mechanical behavior of the breast tissues under compression in real-time

2017

[EN] This work presents a data-driven method to simulate, in real-time, the biomechanical behavior of the breast tissues in some image-guided interventions such as biopsies or radiotherapy dose delivery as well as to speed up multimodal registration algorithms. Ten real breasts were used for this work. Their deformation due to the displacement of two compression plates was simulated off-line using the finite element (FE) method. Three machine learning models were trained with the data from those simulations. Then, they were used to predict in real-time the deformation of the breast tissues during the compression. The models were a decision tree and two tree-based ensemble methods (extremely…

AdultFinite element methodsMean squared errorComputer scienceQuantitative Biology::Tissues and OrgansINGENIERIA MECANICAFinite Element AnalysisPhysics::Medical PhysicsDecision treeBreast compressionHealth Informatics02 engineering and technologyMachine learningcomputer.software_genreModels Biological030218 nuclear medicine & medical imagingSet (abstract data type)03 medical and health sciencesImaging Three-Dimensional0302 clinical medicineMachine learning0202 electrical engineering electronic engineering information engineeringHumansBreastbusiness.industryModelingEnsemble learningFinite element methodComputer Science ApplicationsRandom forestEuclidean distanceTree (data structure)Female020201 artificial intelligence & image processingArtificial intelligenceBreast biomechanicsbusinesscomputerLENGUAJES Y SISTEMAS INFORMATICOS
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LI-RADS: Diagnostic Performance of Hepatobiliary Phase Hypointensity and Major Imaging Features of LR-3 and LR-4 Lesions Measuring 10-19 mm With Arte…

2019

OBJECTIVE. The purpose of this study was to determine the diagnostic performance of hepatobiliary phase hypointensity and Liver Imaging Reporting and Data System (LI-RADS) major imaging features in the diagnosis of hepatocellular carcinoma (HCC) in hepatic lesions with arterial phase hyperenhancement (APHE) measuring 10-19 mm in patients at high risk of HCC. MATERIALS AND METHODS. A composite reference standard of pathologic analysis and imaging follow-up was used. The diagnostic performance (sensitivity and specificity) of hepatobiliary phase hypointensity and LI-RADS major imaging features other than APHE for the diagnosis of HCC was assessed and compared by means of a logistic regression…

AdultGadolinium DTPAMaleGadoxetic acidCirrhosisCarcinoma HepatocellularContrast MediaspecificityliverSensitivity and Specificity030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinemedicineHumansRadiology Nuclear Medicine and imagingIn patientLiver imagingAgedRetrospective StudiesAged 80 and overbusiness.industryLiver NeoplasmsMean ageGeneral Medicinehepatocellular carcinomaMiddle Agedmedicine.diseasesensitivityMagnetic Resonance Imaginggadoxetate disodiumgadoxetic acid030220 oncology & carcinogenesisHepatocellular carcinomaHepatobiliary phaseFemaleNuclear medicinebusinessArterial phasemedicine.drugMRIcirrhosi
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