Search results for "MILD COGNITIVE IMPAIRMENT"

showing 10 items of 65 documents

The instruments used by the Italian centres for cognitive disorders and dementia to diagnose mild cognitive impairment (MCI).

2018

Aims: The purpose of this study was to examine the tools used in Italy to diagnose mild cognitive impairment (MCI). Methods: In collaboration with the Luigi Amaducci Research Consortium, the Italian Network of Alzheimer Evaluation Units prepared a questionnaire to describe how MCI is diagnosed in the Italian Centres for cognitive disorders and dementia (CCDD). Results: Most of the ninety-two CCDDs participating in the survey were located in hospitals (54.7%); large percentages were coordinated by neurologists (50.8%) and geriatricians (44.6%). Almost all (98.5%) used the Mini Mental State Examination to diagnose MCI; the Clock Drawing Test was also frequently used (83.9%). Other neuropsycho…

Malemedicine.medical_specialtyAgingDiagnosis toolStandardized testItalian centres for cognitive disorders and dementia03 medical and health sciences0302 clinical medicineSurveys and Questionnairesmental disordersmedicineDementiaHumansCognitive Dysfunction030212 general & internal medicineMedical diagnosisMild cognitive impairment (MCI)Geriatric AssessmentAgedAged 80 and overMini–Mental State Examinationmedicine.diagnostic_testbusiness.industryNeuropsychologyMild cognitive impairmentCognitionmedicine.diseaseMental Status and Dementia TestsItalyPhysical therapySettore MED/26 - NeurologiaDementiaFemaleGeriatrics and GerontologybusinessClock drawing test030217 neurology & neurosurgeryAging clinical and experimental research
researchProduct

Effects of bilingualism on white matter atrophy in mild cognitive impairment: a diffusion tensor imaging study

2020

Background and purpose Previous investigations show that bilinguals exhibit the first symptoms of dementia 4-5 years later than monolinguals. Therefore, bilingualism has been proposed as a cognitive reserve mechanism. Recent studies have advanced towards an understanding of the brain mechanisms underlying bilingualism's protection against dementia, but none of them deals with white matter (WM) diffusion. Methods In this study, the topic was investigated by measuring WM integrity in a sample of 35 bilinguals and 53 passive bilinguals with mild cognitive impairment. Results No significant differences were found between the groups in cognitive level, education, age or sex. However, bilinguals …

Malemedicine.medical_specialtyBilingualismMildcognitive impairmentMultilingualismAudiologyWhite matter03 medical and health sciences0302 clinical medicineCognitive ReserveFractional anisotropymedicineHumansDementiaCingulum (brain)Cognitive Dysfunction030212 general & internal medicineAgedCognitive reservebusiness.industryFornixBrainmedicine.diseasebilingualism diffusion tensor imaging mild cognitive impairmentWhite MatterDiffusiontensor imagingDiffusion Tensor ImagingBoston Naming Testmedicine.anatomical_structureNeurologyAnisotropyFemaleNeurology (clinical)AtrophyNerve Netbusiness030217 neurology & neurosurgeryDiffusion MRIEuropean Journal of Neurology
researchProduct

Preclinical dementia: an Italian multicentre study on amnestic mild cognitive impairment

2006

<i>Background:</i> Different rates and cognitive predictors of conversion to dementia have been reported in subjects with different kinds of mild cognitive impairment (MCI). <i>Methods:</i> A prospective, 24-month follow-up study, involving 269 subjects who strictly fulfilled criteria for the amnestic MCI. <i>Results:</i> Conversion rate to dementia was 21.4% per year. Seventy-nine out of the 83 individuals who developed dementia were affected by probable Alzheimer’s disease (AD). Among others, at the 24-month follow-up 24.1% were still affected by amnestic MCI, 13.3% had changed their neuropsychological profile of impairment and 17.2% were cognitively no…

Malemedicine.medical_specialtyClinical Dementia RatingCognitive NeuroscienceAudiologyPattern RecognitionNeuropsychological TestsCohort StudiesAlzheimer DiseasePredictive Value of TestsAlzheimer's disease Dementia Mild cognitive impairment NeurospychologymedicineDementiaMemory impairmentHumansMemory disorderProspective StudiesPsychiatryHumans; Alzheimer Disease; Disease Progression; Aged; Predictive Value of Tests; Cognition Disorders; Italy; Verbal Learning; Prospective Studies; Pattern Recognition Visual; Cohort Studies; Follow-Up Studies; Dementia; Neuropsychological Tests; Amnesia; Female; MaleAgedAlzheimer’s disease Mild cognitive impairment Dementia NeurospychologyCognitive disorderNeuropsychologyMild cognitive impairmentCognitionVerbal LearningAlzheimer's diseaseNeurospychologymedicine.diseasePsychiatry and Mental healthPattern Recognition VisualItalyDisease ProgressionFemaleSettore MED/26 - NeurologiaDementiaAmnesiaGeriatrics and GerontologyAlzheimer's diseasePsychologyCognition DisordersVisualFollow-Up Studies
researchProduct

A cross-sectional and longitudinal study on the protective effect of bilingualism against dementia using brain atrophy and cognitive measures.

2020

Abstract Background Evidence from previous studies suggests that bilingualism contributes to cognitive reserve because bilinguals manifest the first symptoms of Alzheimer’s disease (AD) up to 5 years later than monolinguals. Other cross-sectional studies demonstrate that bilinguals show greater amounts of brain atrophy and hypometabolism than monolinguals, despite sharing the same diagnosis and suffering from the same symptoms. However, these studies may be biased by possible pre-existing between-group differences. Methods In this study, we used global parenchymal measures of atrophy and cognitive tests to investigate the protective effect of bilingualism against dementia cross-sectionally …

Malemedicine.medical_specialtyLongitudinal studyBrain atrophyRegion-based morphometryNeurologyBilingualismCognitive NeuroscienceCognitive reserveMultilingualismAudiology050105 experimental psychologylcsh:RC346-429lcsh:RC321-57103 medical and health sciences0302 clinical medicineAtrophymedicineHumansDementia0501 psychology and cognitive sciencesLongitudinal StudiesCognitive declinelcsh:Neurosciences. Biological psychiatry. Neuropsychiatrylcsh:Neurology. Diseases of the nervous systemAgedCognitive reserveBilingüismebusiness.industryResearch05 social sciencesBrainMild cognitive impairmentCognitionMiddle AgedAlzheimer's diseasemedicine.diseaseCognitive testCross-Sectional StudiesMalaltia d'AlzheimerNeurologyDementiaFemaleNeurology (clinical)AtrophybusinessAlzheimer’s disease030217 neurology & neurosurgery
researchProduct

Movements Execution in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease

2007

We evaluated the relationship between motor and neuropsychological deficits in subjects affected by amnestic Mild Cognitive Impairment (aMCI) and early Alzheimer’s Disease (AD). Kinematics of goal-directed movement of aMCI and AD subjects were compared to those of age-matched control subjects. AD showed a slowing down of motor performance compared to aMCI and controls. No relationships were found between motor and cognitive performances in both AD and aMCI. Our results suggest that the different motor behaviour between AD and aMCI cannot be related to memory deficits, probably reflecting the initial degeneration of parietal-frontal circuits for movement planning. The onset of motor dysfunct…

Malemedicine.medical_specialtyMild Cognitive ImpairmentMotor dysfunctionneuropsychologyNeurosciences. Biological psychiatry. NeuropsychiatryDiseaseAudiologyNeuropsychological TestsMotor behaviourSeverity of Illness Indexbehavioral disciplines and activitiesAlzheimer Diseasemental disordersmedicineReaction TimeHumansBiomechanicsClinical NoteAlzheimer’s DiseaseCognitive impairmentalzheimer's disease mild cognitive impairment kinematicsAgedDemographypointingMovement DisordersNeuropsychologyCognitionGeneral MedicineControl subjectsBiomechanical PhenomenaSeverity of Illness Index; Humans; Alzheimer Disease; Aged; Mental Recall; Cognition Disorders; Demography; Movement Disorders; Neuropsychological Tests; Amnesia; Biomechanics; Female; Male; Reaction TimeNeuropsychology and Physiological PsychologyNeurologykinematicsMental RecallSettore MED/26 - NeurologiaFemaleNeurology (clinical)AmnesiaPsychologyCognition DisordersNeuroscienceMovement planningRC321-571Behavioural Neurology
researchProduct

Predictors of progression from mild cognitive impairment to Alzheimer disease.

2007

Objective: To determine the occurrence of neuropsychiatric symptomatology and the relation to future development of Alzheimer disease (AD) in persons with and without mild cognitive impairment (MCI). Method: We followed 185 persons with no cognitive impairment and 47 with MCI (amnestic and multidomain), ages 75 to 95, from the population-based Kungsholmen Project, Stockholm, Sweden, for 3 years. Three types of neuropsychiatric symptoms were assessed at baseline: mood-related depressive symptoms, motivation-related depressive symptoms, and anxiety-related symptomatology. AD at 3-year follow-up was diagnosed according to Diagnostic and Statistical Manual for Mental Disorders-III-R criteria. R…

Malemedicine.medical_specialtyMild Cognitive ImpairmentPopulationNeuropsychological Testsbehavioral disciplines and activitiesDysphoriaCohort StudiesAlzheimer DiseasePredictive Value of TestsRisk FactorsInternal medicinemental disordersmedicinePrevalenceHumanseducationSuicidal ideationAgedAged 80 and overeducation.field_of_studyDepressive DisorderMood Disordersmedicine.diseaseAlzheimer's disease EpidemiologyComorbidityAnxiety DisordersMoodMood disordersDisease ProgressionAnxietySettore MED/26 - NeurologiaFemaleNeurology (clinical)medicine.symptomAlzheimer's diseasePsychologyCognition DisordersClinical psychologyNeurology
researchProduct

Factors associated with mild cognitive impairment in a population-based cohort

2017

Il lavoro non prevede abstract

Malemedicine.medical_specialtyMultivariate analysisNeuropsychological Tests030204 cardiovascular system & hematologyMMSECDTSettore MED/13 - Endocrinologia03 medical and health sciencesPopulation based cohortBMI0302 clinical medicineRisk FactorsInternal medicineInternal MedicinemedicineHumansCognitive DysfunctionLongitudinal StudiesSettore MED/49 - Scienze Tecniche Dietetiche ApplicateCognitive impairmentAgedAged 80 and overbusiness.industryMild cognitive impairmentRegression analysisMiddle AgedCholesterolItalyAnkle-brachial indexCardiovascular DiseasesMultivariate AnalysisABCD studyPhysical therapyRegression AnalysisFemalebusiness030217 neurology & neurosurgery
researchProduct

When the amnestic mild cognitive impairment disappears: characterisation of the memory profile

2009

BACKGROUND/OBJECTIVES: Subjects affected by mild cognitive impairment (MCI) may improve during the observation period. This is the first study investigating qualitative features of memory deficits in subjects affected by reversible MCI [reversible cognitive impairment (RCI)]. METHODS: Baseline cognitive and memory performances of 18 subjects affected by amnestic MCI who had normalized cognitive performances at follow-ups were compared with those of 76 amnestic MCI subjects who still showed impaired cognitive performances at the 24-month follow-up (MCI) and with those of a group of 87 matched control subjects (normal controls). RESULTS: Compared with normal controls the memory deficit in the…

MalememorianeuropsychologyAudiologyNeuropsychological TestsAlzheimer diseaseMemoryMild cognitive impairmentNeuropsychologyPreclinical dementiadeterioramento cognitivo lieveLong-term memoryCognitive disorderNeuropsychologypreclinical dementiaCognitionGeneral MedicinePsychiatry and Mental healthNeuropsychology and Physiological PsychologyMemory Short-TermDisease ProgressionFemaleSettore MED/26 - Neurologiamedicine.symptomAlzheimer's diseasePsychologymedicine.medical_specialtyCognitive NeuroscienceAmnesiaHumans; Alzheimer Disease; Disease Progression; Aged; Mental Recall; Cognition Disorders; Memory; Memory Short-Term; Recognition (Psychology); Psychomotor Performance; Follow-Up Studies; Neuropsychological Tests; Amnesia; Female; MaleRecognition (Psychology)M-PSI/02 - PSICOBIOLOGIA E PSICOLOGIA FISIOLOGICAbehavioral disciplines and activitiesmild cognitive impairmentAlzheimer DiseaseMemorymental disordersNeuropsychologiamedicineHumansMemory disorderAgedMED/26 - NEUROLOGIARecognition Psychologymedicine.diseaseMCInervous system diseasesShort-TermMental Recallmild cognitive impairment; neuropsychology; memory; preclinical dementia; Alzheimer diseaseAmnesiaMED/09 - MEDICINA INTERNACognition Disordershuman activitiesNeurosciencePsychomotor PerformanceFollow-Up Studies
researchProduct

STUDIO DI ASSOCIAZIONE FRA DISLIPIDEMIA, SINDROMI COGNITIVE AMNESTICHE PRE-DEMENZA E MALATTIA DI ALZHEIMER: DATI DI POPOLAZIONE DELLO ZABÙT AGING PRO…

Mild Cognitive ImpairmentMalattia di AlzheimerColesteroloFattori di rischio
researchProduct

Vascular risk factors in Alzheimer’s disease and Mild Cognitive Impairment: population data from the Zabùt Aging Project

Background: Alzheimer's disease (AD) is the most common cause of dementia in older adults, accounting for about 60% of cases. However, autopsy studies suggested that mixed dementia, with vascular and neurodegenerative AD pathology, accounts for nearly 20% of dementia cases. Aims: Aim of the present study was to evaluate the relationship between isolated or clustered Vascular Risk Factors (VRFs)/diseases and Mild Cognitive Impairment (MCI) or AD. The study was conducted using a Sicilian population-based cohort dataset collected in low-educated, rural subjects, the Zabùt Aging Project (ZAP). The effect-modification by age, sex, education, genetic factor (APOE4 allele carrier), undernutrition,…

Mild Cognitive ImpairmentRisk scoresAlzheimer's diseaseVascular Risk Factors
researchProduct