Search results for "MISMATCH NEGATIVITY"
showing 10 items of 182 documents
Spatial Properties of Mismatch Negativity in Patients with Disorders of Consciousness
2018
In recent decades, event-related potentials have been used for the clinical electrophysiological assessment of patients with disorders of consciousness (DOCs). In this paper, an oddball paradigm with two types of frequencydeviant stimulus (standard stimuli were pure tones of 1000 Hz; small deviant stimuli were pure tones of 1050 Hz; large deviant stimuli were pure tones of 1200 Hz) was applied to elicit mismatch negativity (MMN) in 30 patients with DOCs diagnosed using the JFK Coma Recovery ScaleRevised (CRS-R). The results showed that the peak amplitudes of MMN elicited by both large and small deviant stimuli were significantly different from baseline. In terms of the spatial properties of…
Dysfunction of attention switching networks in amyotrophic lateral sclerosis
2019
Objective To localise and characterise changes in cognitive networks in Amyotrophic Lateral Sclerosis (ALS) using source analysis of mismatch negativity (MMN) waveforms. Rationale The MMN waveform has an increased average delay in ALS. MMN has been attributed to change detection and involuntary attention switching. This therefore indicates pathological impairment of the neural network components which generate these functions. Source localisation can mitigate the poor spatial resolution of sensor-level EEG analysis by associating the sensor-level signals to the contributing brain sources. The functional activity in each generating source can therefore be individually measured and investigat…
BENEFITS OF MULTI-DOMAIN FEATURE OF MISMATCH NEGATIVITY EXTRACTED BY NON-NEGATIVE TENSOR FACTORIZATION FROM EEG COLLECTED BY LOW-DENSITY ARRAY
2012
Through exploiting temporal, spectral, time-frequency representations, and spatial properties of mismatch negativity (MMN) simultaneously, this study extracts a multi-domain feature of MMN mainly using non-negative tensor factorization. In our experiment, the peak amplitude of MMN between children with reading disability and children with attention deficit was not significantly different, whereas the new feature of MMN significantly discriminated the two groups of children. This is because the feature was derived from multi-domain information with significant reduction of the heterogeneous effect of datasets.
Representation and Processing of Lexical Tone and Tonal Variants: Evidence from the Mismatch Negativity
2015
Pronunciation variation is ubiquitous in the speech signal. Different models of lexical representation have been put forward to deal with speech variability, which differ in the level as well as the nature of mental representation. We present the first mismatch negativity (MMN) study investigating the effect of allophonic variation on the mental representation and neural processing of lexical tones. Native speakers of Standard Chinese (SC) participated in an oddball electroencephalography (EEG) experiment. All stimuli have the same segments (ma) but different lexical tones: level [T1], rising [T2], and dipping [T3]. In connected speech with a T3T3 sequence, the first T3 may undergo allopho…
Processing of prosodic changes in natural speech stimuli in school-age children.
2012
Speech prosody conveys information about important aspects of communication: the meaning of the sentence and the emotional state or intention of the speaker. The present study addressed processing of emotional prosodic changes in natural speech stimuli in school-age children (mean age 10 years) by recording the electroencephalogram, facial electromyography, and behavioral responses. The stimulus was a semantically neutral Finnish word uttered with four different emotional connotations: neutral, commanding, sad, and scornful. In the behavioral sound-discrimination task the reaction times were fastest for the commanding stimulus and longest for the scornful stimulus, and faster for the neutra…
Validating rationale of group-level component analysis based on estimating number of sources in EEG through model order selection
2012
This study addresses how to validate the rationale of group component analysis (CA) for blind source separation through estimating the number of sources in each individual EEG dataset via model order selection. Control children, typically reading children with risk for reading disability (RD), and children with RD participated in the experiment. Passive oddball paradigm was used for eliciting mismatch negativity during EEG data collection. Data were cleaned by two digital filters with pass bands of 1-30 Hz and 1-15 Hz and a wavelet filter with the pass band narrower than 1-12 Hz. Three model order selection methods were used to estimate the number of sources in each filtered EEG dataset. Un…
Fractionating auditory priors: A neural dissociation between active and passive experience of musical sounds
2019
Learning, attention and action play a crucial role in determining how stimulus predictions are formed, stored, and updated. Years-long experience with the specific repertoires of sounds of one or more musical styles is what characterizes professional musicians. Here we contrasted active experience with sounds, namely long-lasting motor practice, theoretical study and engaged listening to the acoustic features characterizing a musical style of choice in professional musicians with mainly passive experience of sounds in laypersons. We hypothesized that long-term active experience of sounds would influence the neural predictions of the stylistic features in professional musicians in a distinct…
Event-related potentials to tones show differences between children with multiple risk factors for dyslexia and control children before the onset of …
2015
Multiple risk factors can affect the development of specific reading problems or dyslexia. In addition to the most prevalent and studied risk factor, phonological processing, also auditory discrimination problems have been found in children and adults with reading difficulties. The present study examined 37 children between the ages of 5 and 6, 11 of which had multiple risk factors for developing reading problems. The children participated in a passive oddball EEG experiment with sinusoidal sounds with changes in sound frequency, duration, or intensity. The responses to the standard stimuli showed a negative voltage shift in children at risk for reading problems compared to control children…
A potential real-time procedure to evaluate correlation of recordings among single trials (CoRaST) for mismatch negativity (MMN) with Fourier transfo…
2011
Abstract Objective To design a fast algorithm that evaluates the degree of correlation of recordings among single trials (CoRaST) for mismatch negativity (MMN) activity. Methods The participants were 114 children, aged 8–16 years. MMNs were elicited by two deviants in duration that occurred in an uninterrupted sound within a passive oddball paradigm, and each trial lasted 650 ms with 130 samples. CoRaST was derived from the frequency-domain MMN model through Fourier transformation. To validate the effectiveness of the proposed method, the wavelet transformation-based inter-trial coherence (ITC) was taken as a reference. Results Performances of the proposed CoRaST and ITC were similar in eva…
Enhanced development of auditory change detection in musically trained school-aged children: a longitudinal event-related potential study
2013
Adult musicians show superior auditory discrimination skills when compared to non-musicians. The enhanced auditory skills of musicians are reflected in the augmented amplitudes of their auditory event-related potential (ERP) responses. In the current study, we investigated longitudinally the development of auditory discrimination skills in musically trained and nontrained individuals. To this end, we recorded the mismatch negativity (MMN) and P3a responses from children who play a musical instrument and age-matched children with no musical training at ages 7, 9, 11, and 13. Basic auditory processing was investigated by recording ERPs in the Multi-Feature Paradigm that included frequency, du…