Search results for "MISMATCH NEGATIVITY"
showing 10 items of 182 documents
Optimal Digital Filtering versus Difference Waves on the Mismatch Negativity in an Uninterrupted Sound Paradigm
2007
Conventionally, mismatch negativity (MMN) is analyzed through the calculation of the difference waves. This helps to eliminate some exogenous event-related potential (ERP) components. However, this reduces the signal-to-noise ratio (SNR). This study aims to test whether or not the optimal digital filtering performs better than the difference waves procedure in quantitative ERP analyses in an uninterrupted sound paradigm. The participants were 102 children aged 8-16 years. The MMN was elicited in a passive oddball paradigm presenting an uninterrupted sound consisting of two alternating tones (600 and 800 Hz) of the same duration (100 msec) with infrequent shortenings of one of the 600 Hz ton…
Cognitive flexibility modulates maturation and music-training-related changes in neural sound discrimination
2015
Previous research has demonstrated that musicians show superior neural sound discrimination when compared to non-musicians, and that these changes emerge with accumulation of training. Our aim was to investigate whether individual differences in executive functions predict training-related changes in neural sound discrimination. We measured event-related potentials induced by sound changes coupled with tests for executive functions in musically trained and non-trained children aged 9-11 years and 13-15 years. High performance in a set-shifting task, indexing cognitive flexibility, was linked to enhanced maturation of neural sound discrimination in both musically trained and non-trained chil…
Children's brain responses to sound changes in pseudo words in a multifeature paradigm.
2011
Abstract Objective The multifeature mismatch negativity (MMN) paradigm has previously been used to study MMN responses to changes in tones or isolated syllables. We tested 4–12year old children's MMNs to changes in a naturally produced pseudo word context. Methods We studied preschoolers' (under the age of 7years, N =15, mean age 5years 4months) and school childrens' (over the age of 7years, N =15, mean age 9years 3months) MMNs to five types of changes (vowel duration, fundamental frequency, gap, intensity, vowel identity) in the middle syllable of a pseudo word [tɑtɑtɑ] using a multifeature paradigm. Results Vowel duration and gap changes elicited larger frontocentral MMN responses than ot…
Diagnostic subgroups of developmental dyslexia have different deficits in neural processing of tones and phonemes.
2004
The present study addressed auditory processing in 8-11-year-old children with developmental dyslexia by means of event-related brain potentials (ERP). Cortical sound reception was evaluated by recording N250 responses to syllables and tones and cortical sound discrimination by analyzing the mismatch negativity (MMN) to syllable and tone changes. We found that both cortical sound reception and sound discrimination were impaired in dyslexic children. The analysis of the data obtained from two dyslexic subgroups, Dyslexics-1 being impaired in non-word reading (or both non-word and frequent word reading) and Dyslexics-2 in frequent word reading but not in non-word reading, revealed that the MM…
Maturational effects on newborn ERPs measured in the mismatch negativity paradigm.
2003
Abstract The mismatch negativity (MMN) component of event-related potentials (ERPs), a measure of passive change detection, is suggested to develop early in comparison to other ERP components, and an MMN-like response has been measured even from preterm infants. The MMN response in adults is negative in polarity at about 150–200 ms. However, the response measured in a typical MMN paradigm can also be markedly different in newborns, even opposite in polarity. This has been suggested to be related to maturational factors. To verify that suggestion, we measured ERPs of 21 newborns during quiet sleep to rarely occurring deviant tones of 1100 Hz (probability 12%) embedded among repeated standard…
Auditory event-related potentials at preschool age in children born very preterm.
2014
Abstract Objective To assess auditory event-related potentials at preschool age in children born very preterm (VP, 27.4±1.9 gestational weeks, n =70) with a high risk of cognitive dysfunction. Methods We used an oddball paradigm consisting of a standard tone randomly replaced by one of three infrequent deviants (differing in frequency, sound direction or duration). Results The P1 and N2 latencies were inversely correlated to age (50–63months) both in VP ( r =−0.451, p r =−0.305, p= 0.01, respectively) and term born controls (TC; n =15). VP children had smaller P1 than near-term ( n =12) or TC (1.70±0.17μV vs 2.68±0.41 and 2.92±0.43, respectively; p Conclusions Our data suggest a fast matura…
Does mismatch negativity show differences in reading-disabled children compared to normal children and children with attention deficit?
2007
An auditory event-related potential (ERP) component called mismatch negativity (MMN) was examined in three groups of children (n = 63) aged 8-14 years. A control group comprised healthy children in second or sixth grade of comprehensive school (n = 21). The two clinical groups included children with reading disability (RD) (n = 21) and children with attention deficit (AD) (n = 21). MMN was elicited in a passive oddball paradigm by duration changes in a continuous sound, consisting of two alternating (600 and 800 Hz) 100 msec tones. The deviant tones were either 30 or 50 msec in duration. Both deviants elicited a clear MMN in all groups. Statistical analyses showed no systematic difference i…
Mismatch negativity (MMN) elicited by duration deviations in children with reading disorder, attention deficit or both.
2007
According to several studies auditory discrimination as measured by mismatch negativity (MMN) is compromised in participants with reading disorder. However, studies on duration discrimination have produced conflicting findings [Baldeweg, T., Richardson, A., Watkins, S., Foale, C., & Gruzelier, J., 1999. Impaired auditory frequency discrimination in dyslexia detected with mismatch evoked potentials. Annals of Neurology, 4, 1-9; Corbera, S., Escera, C., & Artigas, J., 2006. Impaired duration mismatch negativity in developmental dyslexia. Neuroreport, 17, 1051-1055]. Auditory sensitivity has not been as actively investigated among children with attention deficit, although attention problems of…
Music and speech listening enhance the recovery of early sensory processing after stroke.
2010
Abstract Our surrounding auditory environment has a dramatic influence on the development of basic auditory and cognitive skills, but little is known about how it influences the recovery of these skills after neural damage. Here, we studied the long-term effects of daily music and speech listening on auditory sensory memory after middle cerebral artery (MCA) stroke. In the acute recovery phase, 60 patients who had middle cerebral artery stroke were randomly assigned to a music listening group, an audio book listening group, or a control group. Auditory sensory memory, as indexed by the magnetic MMN (MMNm) response to changes in sound frequency and duration, was measured 1 week (baseline), 3…
Fast measurement of auditory event-related potential profiles in 2–3-year-olds
2012
Auditory discrimination, memory, and attention-related functions were investigated in healthy 2-3-year-olds by recording event-related potentials (ERPs) to changes in five auditory features and two types of novel sounds using the fast multifeature paradigm (MFP). ERP profiles consisting of the mismatch negativity (MMN), P3a, and prominent late discriminative negativities (LDN) were obtained, for the first time, from this age group in a considerably shorter time compared to the traditional paradigms. Statistically significant responses from individual children were obtained mainly for the novel sounds. Thus, the MFP shows promise as a time-efficient paradigm for investigating central auditor…