Search results for "MITO"
showing 10 items of 2513 documents
Le imagini de i dei de gli Antichi : nelle quali si contengono gl'Idoli, i Riti, le ceremonie, & altre cose appartenenti 'alla religioni de gli Antic…
1587
Sign.: a-c4, d6, A-Z4, AA-ZZ4, AAA-ZZZ4, AAAA4 Grav. al llarg del text Caplletres
XII Sibyllarum icones elegantissimi / à Crispiano Passaeo Zelando delineati, ac tabulis aeneis in lucem editi ...
1601
Les f. de grav. i la port. calc. Sign.: [ ]2, A-F4
El mundo vegetal en la mitología clásica y su representación artística
2005
La representación artística de los contenidos de la mitología clásica ofrece innumerables temas de estudio entre los que se encuentra la presencia del mundo vegetal. A partir de las referencias literarias de la Antigüedad, enriquecidas e interpretadas especialmente desde el siglo XVI, el presente artículo explica cómo un buen número de árboles, plantas y flores se convirtieron en atributos de dioses y héroes, bien como símbolo de sus virtudes o de sus actividades. (A)
El "mito de Hércules" como espejo doctrinal. Representaciones del "Mito de Hércules" en la "Sala Nova del "Palau de la Generalitat Valenciana"
1995
La llamada "Sala Nueva" del Palacio de la Generalidad Valenciana conserva un artesonado que es una obra espléndida de la escultura renacentista. Fue realizado por Genís Linares y sus colaboradores, entre los que está Gaspar Gregori. El artesonado se completa con un corredor o galería, también de una gran riqueza escultórica. En la obra se desarrolla un importante y culto programa sobre la problemática de la lucha del Bien contra el Mal; combate entre la Virtud y el Vicio en el que la Virtud termina triunfando siempre. Ese programa se desenvuelve en cuatro tiempos o ciclos: Antiguo o bíblico, Clásico, Medieval y Moderno. En el ciclo Clásico hay que destacar varios temas mitolóticos. Uno de l…
Louisa S. McCord's Caius Gracchus: A Transatlantic Southern Literary Response to 1848 European Revolutions
2016
Louisa S. McCord is the most important female intellectual in the antebellum South and one of its most recognized voices, even if her name rarely appears in studies not directly related to her region. McCord has a parallel, according to Mary Kelley, in Margaret Fuller, the relevant prewar Northern intellectual and essayist. From contrasting ideological positions, both left testimony of their interest in constructing a model of womanhood, capable of facing the contingencies of their times. Born in one of the most influential families of South Carolina, McCord produced a phenomenal synthesis of the conservative political, economic and religious arguments accepted in her times and managed to t…
Mitotic Recombination and Genetic Changes in Saccharomyces cerevisiae during Wine Fermentation
2000
Natural strains of Saccharomyces cerevisiae are prototrophic homothallic yeasts that sporulate poorly, are often heterozygous, and may be aneuploid. This genomic constitution may confer selective advantages in some environments. Different mechanisms of recombination, such as meiosis or mitotic rearrangement of chromosomes, have been proposed for wine strains. We studied the stability of the URA3 locus of a URA3/ura3 wine yeast in consecutive grape must fermentations. ura3/ura3 homozygotes were detected at a rate of 1 x 10(-5) to 3 x 10(-5) per generation, and mitotic rearrangements for chromosomes VIII and XII appeared after 30 mitotic divisions. We used the karyotype as a meiotic marker an…
Synthesis, cytotoxicity, and inhibitory effects on tubulin polymerization of a new 3-heterocyclo substituted 2-styrylquinazolinones
2004
In order to study the influence of 3-substitution on the cytotoxic activity of 2-styrylquinazolinones, new 6-chloro-2-styryl-3-(heteroaryl)-4(3H)-quinazolinones were synthesized by refluxing equimolar amounts of 6-chloro-2-methyl-3-(heteroaryl)-4(3H)-quinazolinones and benzaldehyde in glacial acetic acid. At 1 microg ml(-1) concentration, almost all 2-styrylquinazolinones showed some cytotoxic activity against the L1210 and K562 leukemia cell lines. However, only 6-chloro-2-styryl-3-(pyrimidin-2yl)-4(3H)-quinazolinone inhibited the growth of these cells by over 50%. This last compound was also the only member of the series that inhibited tubulin polymerization, with an IC(50) value of 5.8 v…
Isoindolo[2,1-a]quinoxaline derivatives, novel potent antitumor agents with dual inhibition of tubulin polymerization and topoisomerase I.
2008
Isoindoloquinoxalines 4 and 5 were obtained by refluxing 2-(2'-aminoaryl)-1-cyanoisoindoles 3a- e in acetic or formic acid. All derivatives were screened by the National Cancer Institute (Bethesda, MD) for the in vitro one dose primary anticancer assay against a 3-cell line panel. Compounds 4a- e, screened against a panel of about 60 human tumor cell lines, showed remarkable antineoplastic activity; they had GI 50 values in the low micromolar or submicromolar range and reached, in the case of 4c, nanomolar concentrations on 88% of the 59 tested cell lines. Flow cytometric analysis of cell cycle after treatment with 4c demonstrated an arrest of the cell cycle in G2/M phase. This effect was a…
The Impact of CdS Nanoparticles on Ploidy and DNA Damage of Rucola (Eruca sativa Mill.) Plants
2015
The genotoxic effect of cadmium sulfide nanoparticles (CdS NPs) of different sizes in rucola (Eruca sativaMill.) plants was assessed. It was confirmed that nanoparticles < 5 nm in size were more toxic than larger particles at an identical mass concentration. Significant differences in cell ploidy, as well as in the mitotic index, were detected between control and treated samples. Differences in the DNA banding pattern between control samples and samples after treatment with cadmium sulfide nanoparticles were significant and detected at different places as the appearance or elimination of DNA fragments. Fluorescence images showed that cadmium sulfide nanoparticles smaller than 5 nm in siz…
Assessment in vitro of cytogenetic and genotoxic effects of propolis on human lymphocytes
2012
We evaluated the genetic damage by ethanolic extract of propolis (EEP) induced to human lymphocytes which were exposed to increasing concentrations (0–2000 μg ml−1). The results indicated that EEP reduced significantly the mitotic index (MI) and proliferation index (PI) when high concentrations of EEP were used. Sister chromatid exchange (SCE) rates indicated that EEP could have genotoxic effects at high concentrations. Exposure of the cells to the amount of ethanol used as solvent did not alter either the MI and cell proliferation kinetics (CPK), or the rate of SCE. The results showed: (a) statistical increase in the percentage the cells with CAs and in the frequency of SCE at the highest …