Search results for "ML"
showing 10 items of 1465 documents
XML-dokumenttien koostaminen : havaintoja opinto-opas -projektista
2005
Studerandes åsikter om den obligatoriska språkpraktiken i svenska språket
2017
Tämän tutkimuksen tarkoitus oli ottaa selvää, mitä mieltä ruotsin opiskelijat ovat kieliharjoittelusta, joka on pakollinen osa ruotsin aineopintoja. Tutkimuksessa tarkasteltiin, mitkä seikat vaikuttavat kieliharjoittelutavan valintaan, millaista hyötyä opiskelijat kokevat saaneensa kieliharjoittelusta ja kuinka positiiviseksi opiskelijat arvioivat harjoittelun kokemuksena. Lisäksi tutkittiin opiskelijoiden kielitaidon kehitystä itsearviointien avulla sekä opiskelijoiden mielipiteitä harjoittelun tavoitteiden toteutumisesta. Tutkimukseen osallistui 19 henkilöä. Aluksi kaikki vastasivat sähköiseen kyselylomakkeeseen ja myöhemmin kuusi henkilöä valittiin vielä tarkempaan suulliseen haastattelu…
Genetic profile and immunohistochemical study of clear cell renal carcinoma: Pathological-anatomical correlation and prognosis.
2021
Abstract Introduction Renal cell carcinoma (RCC) accounts for 2–3% of all tumors being the most frequent solid lesion in the kidney. Objective To determine what genetic alterations and immunohistochemical (IHC) of clear cell renal carcinoma (ccRCC) are associated with prognosis and tumor aggressiveness. Patients and Methods Experimental analytical study with 57 patients who underwent radical and partial nephrectomy between 2005 and 2011, all with diagnosis of ccRCC and minimum post-operative follow-up of 36 months. The pathological study included IHC determination of biomarkers associated (CAIX, CAM 5.2, CD10, c-erbB-2, EGFR, HIF-1a, Ki67, MDM2, PAX-2 y 8, p53, survivin and VEGFR 1 and 2). …
Intron variants of the p53 gene are associated with increased risk for ovarian cancer but not in carriers of BRCA1 or BRCA2 germline mutations
1999
Two biallelic polymorphisms in introns 3 and 6 of the p53 gene were analysed for a possible risk-modifying effect for ovarian cancer. Germline DNA was genotyped from 310 German Caucasian ovarian cancer patients and 364 healthy controls. We also typed 124 affected and 276 unaffected female carriers with known deleterious BRCA1 or BRCA2 germline mutation from high-risk breast-ovarian cancer families. Genotyping was based on PCR and high-resolution gel electrophoresis. German ovarian cancer patients who carried the rare allele of the MspI restriction fragment length polymorphism (RELP) in intron 6 were found to have an overall 1.93-fold increased risk (95% confidence internal (CI) 1.27–2.91) w…
Maskulinitāte mūsdienu Latvijas vīriešu autoru dzejā
2019
Maģistra darbā tiek pētīta pēdējo desmit gadu (2008–2018) publicētā vīriešu autoru dzeja, ko sarakstījuši autori vecumā no 30–40 gadiem (1979.–1988. gada paaudze), ar nolūku izpētīt to, kādos veidos tiek atainota maskulinitāte šajā mākslas formā, kā šie atainojumi atšķiras gan viena autora daiļrades ietvaros, gan arī starp dažādu autoru darbiem un kā maskulinitātes atveide ir attīstījusies šajā laika ietvarā. Maģistra darbs ir iecerēts kā teorētisks un praktisks ievads maskulinitātes pētīšanai dzejā, kas līdz šim ir tikusi atstāta novārtā, salīdzinot ar femīno aspektu pētīšanu. Pētījumā tiek secināts, ka attiecīgi konkrēta hegemonija un dzimumlomas var visizteiktāk parādīties attiecībā uz s…
Image classification based on 2D feature motifs
2013
The classification of raw data often involves the problem of selecting the appropriate set of features to represent the input data. In general, various features can be extracted from the input dataset, but only some of them are actually relevant for the classification process. Since relevant features are often unknown in real-world problems, many candidate features are usually introduced. This degrades both the speed and the predictive accuracy of the classifier due to the presence of redundancy in the candidate feature set. In this paper, we study the capability of a special class of motifs previously introduced in the literature, i.e. 2D irredundant motifs, when they are exploited as feat…
Tout savoir sur le treat and extend : organisation et optimisation. Les Cahiers d'Ophtalmologie
2019
La dégénérescence maculaire liée à l’âge (DMLA) est actuellement la première cause de handicap visuel dans les pays développés chez les plus de 50 ans. Elle touche en effet environ 8% de la population française et plus de 25% des plus de 75 ans. La constatation d’une insuffisance de traitement lors d’un régime « réactif » a poussé les cliniciens à proposer d’autres types de régimes. Le « Treat and Extend » (T&E) est né de la volonté d’adapter les intervalles de retraitement des patients pour une prise en charge plus personnalisée.
Testing for Lynch Syndrome in Endometrial Carcinoma: From Universal to Age-Selective MLH1 Methylation Analysis
2022
Simple Summary International guidelines recommend universal screening of endometrial carcinoma patients for Lynch syndrome, a hereditary cancer predisposition syndrome. Screening is based on mismatch repair protein immunohistochemistry and reflex MLH1 methylation analysis to exclude the likely sporadic cases of MMR deficiency. As sporadic MLH1 protein loss is common in endometrial carcinoma, the ability to target methylation testing would save efforts and costs. We discovered that limiting methylation testing to patients under 65 years would have significantly reduced the testing effort while maintaining a low false negative rate for MLH1-LS detection (0% and 3% in our clinic and registry-b…
Mądrościowe odczytanie przykazania: "Nie mów fałszywego świadectwa przeciw bliźniemu swemu" (WJ 20,16; PWT 5,20) w Księdze Przysłów
2015
Przykazania w biblijnym Izraelu stanowiły trwały fundament relacji z Bogiem i z drugim człowiekiem, będąc tym samym podstawowym elementem formowania się społeczności ludzkiej. W tym względzie przykazanie „Nie mów fałszywego świadectwa przeciw bliźniemu swemu”, nabierało szczególnej wartości. Wielość i różnorodność sytuacji skłaniała do prawnych uściśleń, czego potwierdzeniem jest kodeks praw w Księdze Wyjścia i w Księdze Powtórzonego Prawa. Równie ważny był jednak w ludzie wybranym proces kształcenia i formowania poprzez przyswajane mądrościowe sentencje i przysłowia, które przyczyniały się do ukształtowania właściwych postaw. Częste w Księdze Przysłów nawiązywanie do potrzeby składania pra…