Search results for "ML"

Tool support for MOLA

2006

AbstractThe paper describes the MOLA Tool, which supports the model transformation language MOLA. MOLA Tool consists of two parts: MOLA definition environment and MOLA execution environment. MOLA definition environment is based on the GMF (Generic Modeling Framework) and contains graphical editors for metamodels and MOLA diagrams, as well as the MOLA compiler. The main component of MOLA execution environment is a MOLA virtual machine, which performs model transformations, using an SQL database as a repository. The execution environment may be used as a plug-in for Eclipse based modeling tools (e.g., IBM Rational RSA). The current status of the tool is truly academic.

POMDP failu konvertācija un apstrāde

2017

Bakalaura darba nosaukums ir “POMDP failu konvertācija un apstrāde”. Darbā tiek aprakstīti MDP un POMDP modeļi, POMDPx un POMDP failu formāti un šo failu formātu savstarpējai konvertācija, izmantojot programmēšanas valodu C++.

Using a Multi-Locus Microsatellite Typing method improved phylogenetic distribution of Candida albicans isolates but failed to demonstrate associatio…

2012

EA MERS CT3 Enjeu 3; International audience; The dimorphic yeast Candida albicans is a component of the normal microflora at the mucosal surfaces of healthy individuals. It possesses an array of phenotypic properties considered as virulence traits that contribute to pathogenicity of the yeast in immuno-compromised patients. We addressed the question of the pathogenicity of lineages of C. albicans with regard to their genotype in three series of C. albicans isolates (a series of commensal isolates collected in healthy individuals, a group of bloodstream isolates and a group of non-bloodstream clinical isolates) using a Multi-Locus Microsatellite Typing (MLMT) approach based on the analysis o…

MODELADO DE UNA PLATAFORMA DE E-MANTENIMIENTO, CMMS Y CBM

2014

The information and communications technologies (ICT) are increasingly used in society and business. ICT have become a key element for business development and the improvement of activities in all departments. Analogously, the rise of Computerized Maintenance Management Systems (CMMS), Condition Based Maintenance (CBM), and the use of remote devices and functions such as e-maintenance, have opened great possibilities for maintenance optimization. Those techniques have resulted in the emergence of technological challenges such as interoperability between different systems in order to exchange and coordinate information. In this context, the application of business process modelling is a cruc…

Symplekin, a polyadenylation factor, prevents MOZ and MLL activity on HOXA9 in hematopoietic cells

2013

International audience; MOZ and MLL encoding a histone acetyltransferase and a histone methyltransferase, respectively, are targets for recurrent chromosomal translocations found in acute myeloblastic or lymphoblastic leukemia. We have previously shown that MOZ and MLL cooperate to activate HOXA9 gene expression in hematopoietic stem/progenitors cells. To dissect the mechanism of action of this complex, we decided to identify new proteins interacting with MOZ. We found that the scaffold protein Symplekin that supports the assembly of polyadenylation machinery was identified by mass spectrometry. Symplekin interacts and co-localizes with both MOZ and MLL in immature hematopoietic cells. Its …

Region of interest detection using MLP

2014

A novel technique to detect regions of interest in a time series as deviation from the characteristic behavior is proposed. The deterministic form of a signal is obtained using a reliably trained MLP neural network with detailed complexity management and cross-validation based generalization assurance. The proposed technique is demonstrated with simulated and real data. peerReviewed

Extracellular Vesicles From Liver Progenitor Cells Downregulates Fibroblast Metabolic Activity and Increase the Expression of Immune-Response Related…

2021

Extracellular vesicles (EVs) mediate cell-to-cell crosstalk whose content can induce changes in acceptor cells and their microenvironment. MLP29 cells are mouse liver progenitor cells that release EVs loaded with signaling cues that could affect cell fate. In the current work, we incubated 3T3-L1 mouse fibroblasts with MLP29-derived EVs, and then analyzed changes by proteomics and transcriptomics. Results showed a general downregulation of protein and transcript expression related to proliferative and metabolic routes dependent on TGF-beta. We also observed an increase in the ERBB2 interacting protein (ERBIN) and Cxcl2, together with an induction of ribosome biogenesis and interferon-relate…

Analisi di delezioni esoniche del gene PAH in pazienti affetti da iperfenilalaninemia

2009

MONOCYTES MACROPHAGES EXPRESSION OF Ml OR M2 PHENOTYPES IN LATENT TUBERCULOSIS, ACTIVE DISEASES AND UNINFECTED MIGRANTS AND SICILIAN PATIENTS

2016

The high grade ofphenotype plasticity of monocytes macrophages, is resumed in two different cell subsets named M1 or M2. Several studies of microbial infections in vitro and in vivo, showed that, during the early stage of infection, macrophages are polarized toward Ml phenotype that should be protective against pathogen, while during the chronic phase of infection/disease macrophages polarize toward M2 phenotype to avoid damages from a prolonged Ml type activation.Obiettivo: In order to investigate if Mycobacterium tuberculosis infection can drive circulating monocytes toward the expression of Ml or M2 phenotypes, we have analyzed by flow cytometry monocytes obtained from patients with acti…

Power-aware design of MCML logarithmic adders

2010

This paper describes the low-power design of a MOS current-mode logarithmic adder. The adder utilizes the Brent-Kung tree structure. The design strategy adopted is very simple and effective. Moreover, it can be utilized also for other types of logarithmic adders. To validate it, several adders were designed in a TSMC CMOS 130nm technology. Results of simulations indicate that the proposed methodology offers a good starting point before fine-tuning the design by SPICE simulations. Finally, the tradeoff that can be realized between performance and power consumption is discussed.