Search results for "MODERATE"
showing 10 items of 207 documents
Preliminary assessment of an integrated SMOS and MODIS application for global agricultural drought monitoring
2020
An application of the Soil Moisture Agricultural Drought Index (SMADI) for global agricultural drought monitoring is presented. The index integrates surface soil moisture from the Soil Moisture and Ocean Salinity (SMOS) mission with the Moderate Resolution Imaging Spectroradiometer (MODIS) land surface temperature (LST) and Normalized Difference Vegetation Index (NDVI) and allows for global drought monitoring at medium spatial scales (0.05°). Biweekly maps of SMADI were obtained from year 2010 to 2015 over all agricultural areas on Earth. The SMADI time-series were compared with state-of-the-art drought indices over the Iberian Peninsula. Results show a good agreement between SMADI and the …
Modeling Fire Danger in Galicia and Asturias (Spain) from MODIS images
2014
Forest fires are one of the most dangerous natural hazards, especially when they are recurrent. In areas such as Galicia (Spain), forest fires are frequent and devastating. The development of fire risk models becomes a very important prevention task for these regions. Vegetation and moisture indices can be used to monitor vegetation status; however, the different indices may perform differently depending on the vegetation species. Eight different spectral indices were selected to determine the most appropriate index in Galicia. This study was extended to the adjacent region of Asturias. Six years of MODIS (Moderate Resolution Imaging Spectroradiometer) images, together with ground fire data…
A Facile Synthesis of Deaza-Analogues of the Bisindole Marine Alkaloid Topsentin
2013
A series of substituted ethyl 1-[(tert-butoxycarbonyl)amino]-2-methyl-5- (1-methyl-1H-indol-3-yl)-4-[(1-methyl-1H-indol-3-yl)carbonyl]-1H-pyrrole-3-carboxylates were prepared in excellent yields (82-98%) by one-pot reactions between β-dicarbonyl compounds 12a-e and 1,2-diaza-1,3-diene (DD) 13. Derivatives 10a,c-e, deazaanalogues of the bis-indole alkaloid topsentin, screened by the National Cancer Institute (Bethesda, MD, USA) in the in vitro one dose primary anticancer assay against a panel of about 60 human tumor cell lines, showed no significant activity, with the exception of compound 9e, which showed moderate activity against the HOP-92 cell line of the non small cell lung cancer sub-p…
MODIS-Based Monthly LST Products over Amazonia under Different Cloud Mask Schemes
2016
One of the major problems in the monitoring of tropical rainforests using satellite imagery is their persistent cloud coverage. The use of daily observations derived from high temporal resolution sensors, such as Moderate Resolution Imaging Spectroradiometer (MODIS), could potentially help to mitigate this issue, increasing the number of clear-sky observations. However, the cloud contamination effect should be removed from these results in order to provide a reliable description of these forests. In this study the available MODIS Land Surface Temperature (LST) products have been reprocessed over the Amazon Basin (10 N–20 S, 80 W–45 W) by introducing different cloud masking schemes. The mont…
High efficacy and safety of triple therapy in HCV genotype 1 and moderate fibrosis: a multicenter study of clinical practice in Spain.
2015
Background and rational. Telaprevir-based therapy (TBT) has been extensively evaluated in clinical trials. So we designed a study to compare the efficacy and safety of TBT between patients with moderate fibrosis and those suffering from advanced fibrosis in clinical practice. A multicenter observational and ambispective study was conducted. It included 582 patients with chronic hepatitis C genotype 1, 214 with fibrosis F2, and 368 with F3/F4 (F3: 148; F4: 220). Results. The mean patient age was 55 years, 67% male. Type of prior response was 22% naive, 57% relapsers, and 21% partial/null responders, 69% had high viral load (> 800,000 IU/mL). HCV genotypes were 1a (19%), 1b (69%), and 1 (12%)…
Sesquiterpenoids from the Endophytic Fungus Rhinocladiella similis
2019
Ten new sesquiterpenoid derivatives, rhinomilisins A-J (1-10), along with six known analogues (11-16), were isolated from the mangrove-derived endophytic fungus Rhinocladiella similis. The structures of the new compounds were elucidated by their NMR and MS data, while the absolute configuration of 3 and 6 was determined by X-ray crystallographic analysis and Mosher's method, respectively. All isolated compounds (1-16) were evaluated for their cytotoxicity against the mouse lymphoma cell line L5178Y, and compounds 1, 7, and 15 showed moderate activity with IC50 values of 5.0, 8.7, and 24.4 μM, respectively.
Influencia de los distintos tipos y parámetros del ejercicio físico sobre la calidad seminal: una revisión sistemática de la literatura
2019
Es de sobra conocida la importancia positiva de la actividad fisica correctamente prescrita en terminos de intensidad y volumen sobre diferentes alteraciones metabolicas, osteomusculares, cognitivas, etc. La infertilidad es una patologia cuya epidemiologia esta al alza por los cambios en los habitos de nuestra vida cotidiana, como la dieta inadecuada o la radiacion de las nuevas generaciones de aparatos electricos. No existen demasiadas evidencias divulgativas sobre sus causas y efectos, asi como tampoco del papel del ejercicio en la reversion de sus sintomas. Con la finalidad de obtener y sintetizar la informacion mas relevante sobre la influencia de los diferentes tipos y parametros del e…
Incomplete Gestation has an Impact on Cognitive Abilities in Autism Spectrum Disorder
2019
Extreme prematurity is known as a risk factor for autism spectrum disorder (ASD). However, the association between prematurity and ASD, for children born moderately and late preterm (MLPT) and those born early term (ET), is less established. This retrospective study aimed to characterize the phenotypic characteristics (i.e. behavioral profile and cognitive abilities) of 254 children with ASD, between 3 and 15 years of age, born MLPT (19 children), ET (60 children) and full term (175 children). MLPT and ET births do not modify ASD symptomatology, but modify cognitive development. The results highlight that incomplete gestation, i.e., MLPT or ET, has a negative impact on both verbal and nonve…
Changes in hearing in 80-year-old people: a 10-year follow-up study
2004
The aims of this prospective 10-year longitudinal population study were to report changes in hearing in people aged 80 years at baseline, and to assess such changes by comparing results from both cross-sectional and longitudinal analyses. The study population comprised all residents of the city of Jyväskylä born in 1910 (n = 291). The subjects' hearing was tested on three occasions at 5-year intervals with the use of pure-tone audiometry, speech audiometry, and self-report on hearing difficulties. The results showed a significant deterioration in hearing sensitivity in both the longitudinal and cross-sectional assessments over the 10-year follow-up. However, the change in self-assessed hear…
Intergenerational transmission of the positive effects of physical exercise on brain and cognition
2019
Physical exercise has positive effects on cognition, but very little is known about the inheritance of these effects to sedentary offspring and the mechanisms involved. Here, we use a patrilineal design in mice to test the transmission of effects from the same father (before or after training) and from different fathers to compare sedentary- and runner-father progenies. Behavioral, stereological, and whole-genome sequence analyses reveal that paternal cognition improvement is inherited by the offspring, along with increased adult neurogenesis, greater mitochondrial citrate synthase activity, and modulation of the adult hippocampal gene expression profile. These results demonstrate the inher…