Search results for "MORTALITY"

showing 10 items of 1406 documents

Non-Invasive Assessment of Liver Injury in Non-Alcoholic Fatty Liver Disease: A Review of Literature.

2016

NAFLD (Non-Alcoholic Fatty Liver Disease) is an increasingly significant public health issue, regarded as the most relevant liver disease of the twenty-first century. Approximately 20%-30% of NAFLD subjects develop a NASH (Non-Alcoholic Steato-Hepatitis), a condition which can potentially evolve to liver cirrhosis and hepatocellular carcinoma. For these reasons a proper evaluation of liver damage is a key point for diagnosis and prognosis and liver biopsy still remains the "gold standard" procedure both for discrimination between steatosis and steatohepatitis and assessment of the degree of liver fibrosis. Nonetheless, given it is an invasive, painful and costly procedure, a great research …

medicine.medical_specialtyCirrhosisFibrosiBiopsyClinical Decision-MakingApoptosis030204 cardiovascular system & hematologyBiochemistryGastroenterologyMultimodal Imaging03 medical and health sciencesLiver disease0302 clinical medicineNon-alcoholic Fatty Liver DiseaseInternal medicineMedicineAnimalsHumansMortalityMolecular BiologyLiver injurymedicine.diagnostic_testAnimalbusiness.industryFatty liverApoptosiBiomarkerGeneral Medicinemedicine.diseasePrognosisFibrosisdigestive system diseasesAlgorithmLiverLiver biopsyHepatocellular carcinomaMolecular Medicine030211 gastroenterology & hepatologySteatosisSteatohepatitisMorbiditybusinessAlgorithmsBiomarkersHumanCurrent molecular medicine
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Liver transplantation as a primary indication for intrahepatic cholangiocarcinoma: a single-center experience.

2008

Abstract Background Intrahepatic cholangiocarcinoma (ICC) is not a widely accepted indication for orthotopic liver transplantation (OLT). The present study describes our institutional experience with patients who underwent transplantation for ICC as well as those with ICC who underwent transplantation with the incorrect diagnosis of hepatocellular carcinoma (HCC). Patients and Methods Data corresponding to ICC patients were reviewed for the purposes of this study. Patients with hilar cholangiocarcinoma and incidentally found ICC after OLT for benign diseases were excluded from further consideration. Results Among the 10 patients, 6 underwent transplantation before 1996 and 4 after 2001. Tho…

medicine.medical_specialtyCirrhosisTime Factorsmedicine.medical_treatmentMedizinLiver transplantationMilan criteriaGastroenterologyPrimary sclerosing cholangitisCholangiocarcinomaInternal medicinemedicineHepatectomyHumansHospital MortalitySurvivorsSurvival rateIntrahepatic CholangiocarcinomaRetrospective StudiesTransplantationbusiness.industrymedicine.diseaseSurgeryLiver TransplantationTransplantationSurvival Ratesurgical procedures operativeBile Ducts IntrahepaticBile Duct NeoplasmsSurgeryHepatectomybusinessFollow-Up StudiesTransplantation proceedings
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Outcomes of hospitalized patients with COVID-19 according to level of frailty

2021

Background The complications from coronavirus disease 2019 (COVID-19) have been the subject of study in diverse scientific reports. However, many aspects that influence the prognosis of the disease are still unknown, such as frailty, which inherently reduces resistance to disease and makes people more vulnerable. This study aimed to explore the complications of COVID-19 in patients admitted to a third-level hospital and to evaluate the relationship between these complications and frailty. Methods An observational, descriptive, prospective study was performed in 2020. A sample of 254 patients from a database of 3,112 patients admitted to a high-level hospital in Madrid, Spain was analyzed. …

medicine.medical_specialtyComplicationsCoronavirus disease 2019 (COVID-19)lcsh:MedicineDiseaseGeneral Biochemistry Genetics and Molecular Biologylaw.invention03 medical and health sciences0302 clinical medicinelawStatistical significanceInternal MedicinemedicineCoronavirus infection030212 general & internal medicineMortalityProspective cohort studyAgedFrailtybusiness.industrySARS-CoV-2General NeuroscienceMortality ratelcsh:RCOVID-19General MedicinePrognosisIntensive care unitGeriatricsEmergency medicineDeliriumObservational studyPublic Healthmedicine.symptomGeneral Agricultural and Biological Sciencesbusiness030217 neurology & neurosurgery
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Current state of dynamic surgery. A literature review.

2021

Background Recently, dental implant technology has been widely used for oral reconstruction. Dental implants are the treatment of choice for those patients with dental absences. An optimal implant placement is based on the prosthetic driven concept in order to achieve an aesthetic and functional restoration with a long-term prognosis. There are two types of guided implant surgery that are described in the literature: Static Guided Surgery (SGS) and Dynamic Guided Surgery (DGS). The aim of this study is to be aware of the current state of dynamic surgery and compare in the literature the discrepancies between planning and placement of dental implants. Material and Methods The study consists …

medicine.medical_specialtyComputer sciencemedicine.medical_treatmentMEDLINEContext (language use)frailtyReviewEsthetics DentalImplant surgerylaw.inventionhead and neck neoplasmsRandomized controlled triallawpostoperative complicationsmedicineHumansDental implantGeneral DentistryUNESCO:CIENCIAS MÉDICASDental ImplantsDental Implantation EndosseousmortalityOral reconstructionSurgeryImplant placementOtorhinolaryngologySurgeryImplantologyMedicina oral, patologia oral y cirugia bucal
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COVID-19 and obesity: links and risks

2020

Applicable to the fields of endocrinology, as well as for specialists in cardiovascular disease (CVD), obesity has numerous cardiometabolic unfavorable consequences. Obesity is by far the leading c...

medicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Endocrinology Diabetes and MetabolismPneumonia ViralMEDLINEseverityDiseasePeptidyl-Dipeptidase ACOVID-19; Obesity; mortality; prognosis; severityCOVID-19BetacoronavirusMetabolic DiseasesRisk FactorsPandemicHumansMedicineObesityIntensive care medicinePandemicsbiologySARS-CoV-2business.industryViral EpidemiologyCOVID-19biology.organism_classificationmedicine.diseaseObesitymortalityPneumoniaAngiotensin-Converting Enzyme 2prognosisCoronavirus InfectionsbusinessBetacoronavirus
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Impact of COVID-19 pandemic on acute heart failure admissions and mortality: a multicentre study (COV-HF-SIRIO 6 study)

2022

Abstract Aims The coronavirus disease‐2019 (COVID‐19) pandemic has changed the landscape of medical care delivery worldwide. We aimed to assess the influence of COVID‐19 pandemic on hospital admissions and in‐hospital mortality rate in patients with acute heart failure (AHF) in a retrospective, multicentre study. Methods and results From 1 January 2019 to 31 December 2020, a total of 101 433 patients were hospitalized in 24 Cardiology Departments in Poland. The number of patients admitted due to AHF decreased by 23.4% from 9853 in 2019 to 7546 in 2020 (P < 0.001). We noted a significant reduction of self‐referrals in the times of COVID‐19 pandemic accounting 27.8% (P < 0.001), with increase…

medicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Heart failureMedical careLevodopaCOVID‐19Internal medicinePandemicmedicineHumansDiseases of the circulatory (Cardiovascular) systemIn patientPandemicsRetrospective StudiesSARS-CoV-2business.industryMortality rateCarbidopaCOVID-19Original Articlesmedicine.diseaseIn‐hospital mortalityHospitalizationDrug CombinationsIn-hospital mortalityRC666-701Heart failureConcomitantAcute DiseaseOriginal ArticleCardiology and Cardiovascular MedicinebusinessHospital stayESC heart failure
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Why Does COVID-19 Case Fatality Rate Vary Among Countries?

2020

SummaryBackgroundWhile the epidemic of SARS-CoV-2 is spreading worldwide, there is much concern over the mortality rate that the infection induces. Available data suggest that COVID-19 case fatality rate varies temporally (as the epidemic progresses) and spatially (among countries). Here, we attempted to identify key factors possibly explaining the variability in case fatality rate across countries.MethodsWe used data on the temporal trajectory of case fatality rate provided by the European Center for Disease Prevention and Control, and country-specific data on different metrics describing the incidence of known comorbidity factors associated with an increased risk of COVID-19 mortality at …

medicine.medical_specialtyCoronavirus disease 2019 (COVID-19)[SDV]Life Sciences [q-bio]Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Public healthIncidence (epidemiology)Mortality rate010102 general mathematics030204 cardiovascular system & hematologymedicine.disease01 natural sciencesComorbidity3. Good health03 medical and health sciencesCountry level0302 clinical medicineGeographyIncreased riskCase fatality ratemedicineDisease prevention030212 general & internal medicine0101 mathematicsDemographySSRN Electronic Journal
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Mortality associated with cardiovascular disease in patients with COVID-19

2020

Introducción y objetivos: Las enfermedades cardiovasculares (ECV) se han identificado como un factor de riesgo de mal pronóstico en pacientes con infección por COVID-19. Métodos: Se realizó un metanálisis de estudios actualmente disponibles con la prevalencia de ECV en supervivientes frente a no supervivientes en pacientes con infección por COVID-19 hasta el 16 de julio de 2020. Los análisis se realizaron mediante un modelo de efectos aleatorios y sensibilidad. Se realizaron análisis para identificar posibles fuentes de heterogeneidad o evaluar los efectos de los estudios pequeños. Resultados: Se incluyó a 307.596 pacientes de 16 estudios, de los que 46.321 (15,1%) tenían ECV. La tasa de mo…

medicine.medical_specialtyCoronavirus disease 2019 (COVID-19)business.industryMortality rateEnfermedad cardiovascularCOVID-19DiseaseCardiovascular diseasemedicine.diseaseRandom effects modelArticleCoronavirusCVD cardiovascular deseaseInternal medicineDiabetes mellitusMortalidadmedicineRisk of mortalityIn patientMortalityRisk factorCardiology and Cardiovascular MedicinebusinessREC: CardioClinics
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Mortality after in-hospital cardiac arrest in patients with COVID-19: A systematic review and meta-analysis.

2021

Abstract Aim To estimate the mortality rate, the rate of return of spontaneous circulation (ROSC) and survival with favorable neurological outcome in patients with COVID-19 after in-hospital cardiac arrest (IHCA) and attempted cardiopulmonary resuscitation (CPR). Methods PubMed, EMBASE, Web of Science, bioRxiv and medRxiv were surveyed up to 8th February 2021 for studies reporting data on mortality of patients with COVID-19 after IHCA. The primary outcome sought was mortality (in-hospital or at 30 days) after IHCA with attempted CPR. Additional outcomes were the overall rate of IHCA, the rate of non-shockable presenting rhythms, the rate of ROSC and the rate of survival with favorable neuro…

medicine.medical_specialtyCoronavirus disease 2019 (COVID-19)medicine.medical_treatment030204 cardiovascular system & hematologyEmergency Nursing03 medical and health sciences0302 clinical medicinePrimary outcomeInternal medicineHospital dischargeMedicineHumansIn patientcprCardiopulmonary resuscitationMortalitybusiness.industrySARS-CoV-2Neurological statusMortality rateCOVID-19030208 emergency & critical care medicineCardiac arrestCardiopulmonary ResuscitationHospitalsHeart ArrestEditorialMeta-analysisEmergency MedicineCardiology and Cardiovascular MedicinebusinessResuscitation
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High flow nasal therapy in immunocompromised patients with acute respiratory failure: A systematic review and meta-analysis.

2019

Abstract Purpose The role of high-flow nasal therapy (HFNT) as compared to conventional oxygen therapy (COT) in immunocompromised patients admitted to intensive care unit (ICU) with acute respiratory failure (ARF) remains unclear. We conducted a systematic review and meta-analysis in order to address this issue. Methods We searched PubMed, Medline and Embase until November 7th, 2018. Randomized controlled trials (RCTs), non-randomized prospective and retrospective evidence were selected. Observational studies were considered for sensitivity analysis. Primary outcome was mortality rate; intubation rate was a secondary outcome. Results We included four studies in the primary analysis: one RCT…

medicine.medical_specialtyCritical CareAcute respiratory failure High flow nasal cannula High flow nasal therapy Immunocompromised patients Mechanical ventilation Noninvasive ventilation Oxygen therapy Cannula Humans Immunocompromised Host Intubation Intratracheal Noninvasive Ventilation Oxygen Inhalation Therapy Randomized Controlled Trials as Topic Respiratory Distress Syndrome Adult Critical Caremedicine.medical_treatmentAcute respiratory failureCritical Care and Intensive Care Medicinelaw.inventionImmunocompromised Host03 medical and health sciencesMechanical ventilation0302 clinical medicineRandomized controlled triallawInternal medicineOxygen therapyIntubation IntratrachealImmunocompromised patientmedicineCannulaHumansIntubationHigh flow nasal therapyRandomized Controlled Trials as TopicRespiratory Distress Syndromebusiness.industryMortality rateOxygen Inhalation Therapy030208 emergency & critical care medicineRetrospective cohort studyOdds ratioOxygen therapyIntensive care unitHigh flow nasal cannula030228 respiratory systemMeta-analysisbusinessNoninvasive ventilation
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