Search results for "MR"
showing 10 items of 3001 documents
Donellanic acids A–C: new cyclopropanic oleanane derivatives from Donella ubanguiensis (Sapotaceae)
2012
Abstract Three new cyclopropanic oleanane triterpenoids and ten known compounds were obtained from Donella ubanguiensis using chromatographic methods. The structures were established on the basis of mass spectrometric and NMR data and by comparison with values reported in the literature. The structures of the new compounds were confirmed by X-ray crystallography. A part of the isolated compounds was evaluated for cytotoxic and antimicrobial activities.
The C-12 and C-20 configurations of some neo-clerodane diterpenoids isolated from Teucrium species
1986
Abstract A convenient and conclusive method for determining the C-12 stereochemistry of neo-clerodan-20,12-olide derivatives, even when only one epimer is available, is by 1H NMR NOE measurements. The C-12 configuration of 26 neo-clerodane diterpenoids isolated from Teucrium species has been re-examined by using this type of experiment. The results indicated that all the previous assignments were correct, except for teupyreinin, where the previously assigned C-12(S) configuration must be amended to C-12(R). This was confirmed by chemical transformations and additional 1H and 13C NMR studies. Furthermore, the NOE experiments allowed the assignment of a C-20(S) configuration for teuflavin, th…
Bis-urea macrocycles with a deep cavity.
2015
Two configurational isomers of bis-urea macrocycles have been synthesized, and their neutral molecule recognition was studied by X-ray crystallography and (1)H NMR experiments. Cooperative action between the deep cavity and the urea groups and the influence of dipole alignments on molecular recognition are discussed.
Ympäristöestrogeeniseoksen yhteisvaikutus 20dpfZF-seeprakalan vitellogeniinigeenin ilmentymiseen
2011
Ihmisten toimesta ympäristöön joutuvien vierasaineiden vaikutukset hormonitoimintaan ovat viime vuosina herättäneet paljon keskustelua. Yksi alan tutkituimmista aihealueista on estrogeenin kaltaisesti vaikuttavien aineiden eli ympäristöestrogeenien aiheuttamat lisääntymis- ja kehityshäiriöt. Estrogeenisiä vaikutuksia voidaan tutkia monella tapaa, alkaen solutason vasteista populaatiokehitykseen. Yksi paljon käytetty molekyylimarkkeri on kalojen vitellogeniinitason mittaus. Vaikka normaalioloissa vain naaraat tuottavat vitellogeniiniä, estrogeenialtistuksen vaikutuksesta myös koiraat ja nuoret yksilöt voivat sitä tuottaa. Tässä opinnäytetyössä tutkittiin kolmen ympäristöestrogeenin, bisfenol…
Medication-Related Osteonecrosis of Jaws (MRONJ) Prevention and Diagnosis: Italian Consensus Update 2020
2020
The Medication-Related Osteonecrosis of Jaws (MRONJ) diagnosis process and its prevention play a role of great and rising importance, not only on the Quality of Life (QoL) of patients, but also on the decision-making process by the majority of dentists and oral surgeons involved in MRONJ prevention (primary and secondary). The present paper reports the update of the conclusions from the Consensus Conference—held at the Symposium of the Italian Society of Oral Pathology and Medicine (SIPMO) (20 October 2018, Ancona, Italy)—after the newest recommendations (2020) on MRONJ were published by two scientific societies (Italian Societies of Maxillofacial Surgery and Oral Pathology and Medicine, SI…
Saistība starp briofītu funkcionālajām grupām, substrātu īpašībām un mežau augu sabiedrībām Moricsalas dabas rezervātā
2013
Anotācija Darba mērķis ir noskaidrot substrāta parametru ietekmi uz briofītu sugu bagātību, sugu sastopamību un sugu sadalījumu pa funkcionālajām grupām (dzīves formu un dzīves stratēģiju) dažādās meža augu sabiedrībās, kā arī izpētīt sūnu sugu sastāva mainību Moricsalā pēdējo 100 gadu laikā. Par pētāmo teritoriju izvēlēts Moricsalas dabas rezervātā, kas ir senākā aizsargājamā dabas teritorija Latvijā un ilgstoši neskartās dabas dēļ īpaši piemērota sūnu ekoloģijas izpētei. Pašlaik bagātīgu sūnu sugu sastopamību uz pētītajiem substrātiem nodrošina koku sugas ar atšķirīgu mizas reakciju, dažāda garuma un apkārtmēra kritalas, heterogēns koku sugu sastāvs. Pēdējo 100 gadu laikā Moricsalas meža …
Automatic multi-seed detection for MR breast image segmentation
2017
In this paper an automatic multi-seed detection method for magnetic resonance (MR) breast image segmentation is presented. The proposed method consists of three steps: (1) pre-processing step to locate three regions of interest (axillary and sternal regions); (2) processing step to detect maximum concavity points for each region of interest; (3) breast image segmentation step. Traditional manual segmentation methods require radiological expertise and they usually are very tiring and time-consuming. The approach is fast because the multi-seed detection is based on geometric properties of the ROI. When the maximum concavity points of the breast regions have been detected, region growing and m…
Tear <sup>1</sup>H Nuclear Magnetic Resonance-Based Metabolomics Application to the Molecular Diagnosis of Aqueous Tear Deficiency and Me…
2020
<b><i>Purpose:</i></b> Meibomian gland dysfunction (MGD) is a major cause of signs and symptoms related to dry eyes (DE) and eyelid inflammation. We investigated the composition of human tears by metabolomic approaches in patients with aqueous tear deficiency and MGD. <b><i>Methods:</i></b> Participants in this prospective, case-control pilot study were split into patients with aqueous tear deficiency and MGD (DE-MGD [<i>n</i> = 15]) and healthy controls (CG; <i>n</i> = 20). Personal interviews, ocular surface disease index (OSDI), and ophthalmic examinations were performed. Reflex tears collected by capillarity were pr…
High performance of intravoxel incoherent motion diffusion MRI in detecting viral hepatitis-b induced liver fibrosis.
2019
Background: Recently a small cohort study demonstrated that intravoxel incoherent motion (IVIM) diffusion MRI can detect early stage liver fibrosis. Using modified IVIM data acquisition parameters, the current study aims to confirm this finding. Methods: Twenty-six healthy volunteers, three patients of chronic viral hepatitis-b but without fibrosis and one mild liver steatosis subject, and 12 viral hepatitis-b patients with fibrosis (stage 1–2=7, stage 3–4=5) were included in this study. With a 1.5-T MR scanner and respiration-gating, IVIM diffusion imaging was acquired using a single-shot echo-planar sequence with a b -value series of 2, 0, 1, 15, 20, 30, 45, 50, 60, 80, 100, 200, 300, 600…
The Role of Chronic Physical Activity in Alleviating the Detrimental Relationship of Childhood Obesity on Brain and Cognition
2021
Shu-Shih Hsieh was supported by the Postdoctoral Research Abroad Program from the Ministry of Science and Technology in Taiwan (reference number: 109-2917-I-564-034). Francisco B. Ortega's research activity was supported by funds from Spanish Ministry of Economy and Competitiveness (Reference number: DEP2016-79512-R and DEP2017-91544-EXP) and the Andalusian Operational Programme supported with European Regional Development Funds (ERDF in English, FEDER in Spanish, project ref: B-CTS-355-UGR18).