Search results for "MULTIPLE"

Sense of Coherence and Health-Related Quality of Life in Patients with Multiple Sclerosis: The Role of Physical and Neurological Disability

2022

Multiple sclerosis is a progressive demyelinating disease of the central nervous system that can lead to permanent disability and significantly impact the quality of life. The present study explores the relationship between neurological disability and disease symptoms, quality of life, and the level of sense of coherence, which is an important resource for coping with the disease. EDSS, GNDS, SOC-29, and MSIS-29 were used in the presented study. The study group consisted of 137 people diagnosed with multiple sclerosis. The study showed the correlation between most of the analyzed variables. Mood disability and fatigue were significant predictors of the sense of coherence and explained 34% o…

(p,2)-equations resonant at any variational eigenvalue

2018

We consider nonlinear elliptic Dirichlet problems driven by the sum of a p-Laplacian and a Laplacian (a (p,2) -equation). The reaction term at ±∞ is resonant with respect to any variational eigenvalue of the p-Laplacian. We prove two multiplicity theorems for such equations.

Conceptualizing ecosystem tipping points within a physiological framework

2017

Connecting the nonlinear and often counterintuitive physiological effects of multiple environmental drivers to the emergent impacts on ecosystems is a fundamental challenge. Unfortunately, the disconnect between the way “stressors” (e.g., warming) is considered in organismal (physiological) and ecological (community) contexts continues to hamper progress. Environmental drivers typically elicit biphasic physiological responses, where performance declines at levels above and below some optimum. It is also well understood that species exhibit highly variable response surfaces to these changes so that the optimum level of any environmental driver can vary among interacting species. Thus, specie…

Characters with multiple usages- phenotypic variability analysis at Echinacea purpurea (L.) Moench species

2010

Merging aesthetics with utility, some medicinal plants can benefit both of a high production and decoration potential. This calls for diversification of improvement directions of the species. Through this article we suggest one of these species, Echinacea purpurea (L.) Moench. This is considered to be important at this time, acquisition of new biological forms - varieties in this species, which show multiple attributes utility based on key biological characteristics, agronomic, physiological, biochemical and agrochemical (medicinal, decorative, culinary etc.). To achieve this goal, studies were undertaken, given in this article, which is the starting point for selecting characters represent…

Synthesis and application of orthogonal signal bases possessing enhanced timefrequency localization for mobile wireless networks

2012

Quaternary Reversible Circuit Optimization for Scalable Multiplexer and Demultiplexer

2023

Information loss is generally related to power consumption. Therefore, reducing information loss is an interesting challenge in designing digital systems. Quaternary reversible circuits have received significant attention due to their low-power design applications and attractive advantages over binary reversible logic. Multiplexer and demultiplexer circuits are crucial parts of computing circuits in ALU, and their efficient design can significantly affect the processors’ performance. A new scalable realization of quaternary reversible 4×1 multiplexer and 1×4 demultiplexer, based on quaternary 1-qudit Shift, 2-qudit Controlled Feynman, and 2-qudit Muthukrishnan-Stroud gates, is presented in …

"Verkoston pauloissa" : MS-potilaiden kokemuksia tukiverkoston kohtaamisesta kuntoutusprosessin aikana

1998

Phenotypic spectrum and genomics of undiagnosed arthrogryposis multiplex congenital

2022

BackgroundArthrogryposis multiplex congenita (AMC) is characterised by congenital joint contractures in two or more body areas. AMC exhibits wide phenotypic and genetic heterogeneity. Our goals were to improve the genetic diagnosis rates of AMC, to evaluate the added value of whole exome sequencing (WES) compared with targeted exome sequencing (TES) and to identify new genes in 315 unrelated undiagnosed AMC families.MethodsSeveral genomic approaches were used including genetic mapping of disease loci in multiplex or consanguineous families, TES then WES. Sanger sequencing was performed to identify or validate variants.ResultsWe achieved disease gene identification in 52.7% of AMC index pati…

The campomelic syndrome: review, report of 17 cases, and follow-up on the currently 17-year-old boy first reported by Maroteaux et al in 1971.

1983

We report 17 cases of the campomelic syndrome (CS) and a follow-up of one of the original patients of Maroteaux et al who is now 17 years old. Our review is based on 97 patients, including our own. An infant with the CS presents at birth with spectacularly short and bowed femora and tibiae. The initial chest radiograph confirms the diagnosis by demonstrating extremely small bladeless scapulae and hypoplastic pedicles of many thoracic vertebrae. Ossification of the sternal segments, pubis, talus, and knee epiphyses is also retarded. Usually the hips are dislocated and talipes equinovarus deformities are present. There is a small chondrocranium and a disproportionately large neurocranium. The…

Chondrodysplasia punctata, tibia-metacarpal (MT) type.

1990

We describe 7 patients with a new form of chondrodysplasia punctata. Its principal clinical manifestations are flat midface and nose, short limbs, and otherwise normal development. Consistent radiologic manifestations in the newborn infant are discrete calcific stippling, coronal clefts of vertebral bodies, short tibiae, and shortness of the 2nd and 3rd metacarpal bones. Radiologic findings in the older child include shortness of tibiae and the 3rd and 4th metacarpals.