Search results for "Mace"
showing 10 items of 4713 documents
PARTICELLE MICROMETRICHE, LORO METODO DI PREPARAZIONE E LORO USI
2019
La presente invenzione si riferisce a particelle micrometriche comprendenti il decanoato di cetile, al loro metodo di preparazione e a loro usi. In particolare, le particelle dell’invenzione sono utili per favorire l’assorbimento transpiteliale di principi attivi scarsamente solubili e/o permeabili.
Hyaluronic acid based microparticles for applications in regenerative medicine
2018
Assessment of the Inter-Batch Variability of Microstructure Parameters in Topical Semisolids and Impact on the Demonstration of Equivalence
2019
Demonstration of similar microstructure is essential for demonstrating the equivalence of generic topical products since the microstructure of semisolids may affect the drug release. The objective of this study was to compare the microstructure-defining physical parameters of different batches of a reference ointment containing calcipotriol and betamethasone (Daivobet 50 µ
Molecular Modelling Studies on Molecular Pathways Related to Tumorigenesis in the Discovery of New Lead Compounds.
2012
Aktīvo farmaceitisko vielu ķīmiskās struktūras ietekme uz gatavo zāļu formu mikrobioloģiskās tīrības analītiskās metodes izvēli.
2022
Farmaceitiskā mikrobioloģija ir viena no bioloģijas specifiskām nozarēm, kas galvenokārt atbild par gatavo produktu mikrobioloģisko tīrumu. Produkcijas piesārņojums var negatīvi ietekmēt pacienta veselību, līdz ar to ir nepieciešami sterilitātes testi. Šīm nolūkam tiek izveidota monitoringa programma, kas iekļauj sevī telpu un aprīkojumu mazgāšanu, personāla uzraudzību, ūdens un izejvielu mikrobioloģiskās kvalitātes uzraudzību. Darbā tika pētītas vairākas neantibiotisku līdzekļu grupas tādas kā nesteroīdie pretiekaisuma līdzekļi un anestētiķi, bet īpaša uzmanība tika pievērsta produktiem, kuri iedarbojas uz cilvēka centrālo nervu sistēmu. Vispirms tika izvirzītas optimālas metodes aerobo ba…
Reuse of Food Waste: The Chemical Composition and Health Properties of Pomelo (Citrus maxima) Cultivar Essential Oils
2022
The aim of the present study is to investigate the chemical profile, antioxidant activity, carbohydrate-hydrolysing enzyme inhibition, and hypolipidemic effect of essential oils (EOs) extracted from Sicilian Citrus maxima (pomelo) flavedo. Using gas-chromatography-mass spectrometry analysis (GC-MS) we analysed the Eos of five cultivars of C. maxima, namely, ‘Chadock’, ‘Maxima’, ‘Pyriformis’, ‘Terracciani’, and ‘Todarii’, and their blends. The antioxidant activity was performed by using a multi-target approach using 2,2′-Azino-Bis-3-Ethylbenzothiazoline-6-Sulfonic acid (ABTS), 2,2-Diphenyl-1-picrylhydrazyl (DPPH), ferric reduc…
Estudio y evaluación de la estabilidad del alcohol etílico en muestras de sangre almacenadas en condiciones de temperatura de congelación
2015
La determinación del alcohol etílico es una de las analíticas más solicitadas en la toxicología forense y su implicación médico legal es de gran importancia. El alcohol etílico es una sustancia volátil y su estabilidad está influenciada por una serie de factores y/o variables, como son condiciones preanalíticas no adecuadas, difusión y redistribución postmortem y generación o pérdidas de alcohol etílico. En base a estos hechos, se ha planteado la presente Tesis ya que las condiciones de almacenamiento de las muestras de sangre constituyen un factor importante en la estabilidad del alcohol etílico y, por consiguiente, puede influir a la hora de informar un resultado fiable y válido cuando se…
<p>Effects of losartan and atorvastatin on the development of early posttraumatic joint stiffness in a rat model</p>
2019
Background After a trauma, exuberant tissue healing with fibrosis of the joint capsule can lead to posttraumatic joint stiffness (PTJS). Losartan and atorvastatin have both shown their antifibrotic effects in different organ systems. Objective The purpose of this study was the evaluation of the influence of losartan and atorvastatin on the early development of joint contracture. In addition to joint angles, the change in myofibroblast numbers and the distribution of bone sialoprotein (BSP) were assessed. Study design and methods In this randomized and blinded experimental study with 24 rats, losartan and atorvastatin were compared to a placebo. After an initial joint injury, rat knees were …
Adsorption of methotrexate and calcium leucovorin onto cholestyramine in vitro.
2003
Abstract Methotrexate (MTX), an antimetabolite of folic acid, is a drug widely used in the treatment of different types of cancer. When high doses are administered, it is necessary to interrupt its action by administering calcium leucovorin (CaL). The main pathway of MTX and CaL elimination in humans occurs through the kidney, but about 10% is excreted in the faeces via the bile. Drugs, foods and sorbents in intestinal lumen modify MTX and CaL reabsorption. Individual and simultaneous studies on the adsorption of MTX and CaL from aqueous phosphate buffer by cholestyramine were carried out in order to calculate the adsorption process of MTX and CaL to cholestyramine, and to characterize the …
"Accès au médicament et commerce international"
2006
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