Search results for "Mach"

showing 10 items of 3360 documents

OPETH: Open Source Solution for Real-Time Peri-Event Time Histogram Based on Open Ephys

2019

Single cell electrophysiology remains one of the most widely used approaches of systems neuroscience. Decisions made by the experimenter during electrophysiology recording largely determine recording quality, duration of the project and value of the collected data. Therefore, online feedback aiding these decisions can lower monetary and time investment, and substantially speed up projects as well as allow novel studies otherwise not possible due to prohibitively low throughput. Real-time feedback is especially important in studies that involve optogenetic cell type identification by enabling a systematic search for neurons of interest. However, such tools are scarce and limited to costly co…

Cell typeSpeedupComputer scienceBiomedical EngineeringNeuroscience (miscellaneous)peri-event time histogramOptogeneticsMachine learningcomputer.software_genreopen ephys050105 experimental psychologyNeuron typeslcsh:RC321-571Photostimulation03 medical and health sciencesSoftware0302 clinical medicineopen sourceHistogramMethods0501 psychology and cognitive sciencesoptogeneticslcsh:Neurosciences. Biological psychiatry. Neuropsychiatrycomputer.programming_language030304 developmental biologySystems neuroscience0303 health sciencesbusiness.industrybehavior05 social sciencesPattern recognitionPython (programming language)NeurophysiologyelectrophysiologyComputer Science ApplicationsElectrophysiologyOpen sourceCell electrophysiologyArtificial intelligencebusinesscomputer030217 neurology & neurosurgeryNeuroscienceFrontiers in Neuroinformatics
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Immediate and long-term microshear bond strength of resin-based cements to core build-up materials

2021

Background To evaluate the microshear bond strength (μ-SBS) between resin-based cements and core build-up materials after water storage. Material and methods Cylinders (1x1 mm) of conventional dual-cure resin cement (RelyX ARC, 3M ESPE), universal dual-cure resin cement (RelyX Ultimate, 3M ESPE) or self-adhesive resin cement (RelyX U200, 3M ESPE) were adhered to disks (6x2 mm) made with commercial core build-up materials (Bis-Core, Bisco or LuxaCore Z, DMG) or conventional nanocomposite resin (Filtek Z350 XT, 3M ESPE). The specimens (n=10) were submitted to μ-SBS test using a universal testing machine and fracture pattern analysis at 48 hours or after 9 months of water storage. The data wer…

CementChange over timeUniversal testing machineNanocompositeMaterials scienceBond strengthResearchComposite numberCore (manufacturing)Operative Dentistry and EndodonticsAdhesiveComposite materialGeneral DentistryUNESCO:CIENCIAS MÉDICASJournal of Clinical and Experimental Dentistry
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Bond strength according to the moment of fiber post cutting fixed with self-adhesive cement to the root dentin

2021

Background The fiber posts require a cut in the coronal portion to adjust it to the available clinical space. The cutting of posts cemented may generate tension via bur vibrations of drill on the bonding interface, with the possibility of decreasing the bond strength. Thus, this study aimed to evaluate if the moment of cutting the fiber posts has an effect on its bond strength when fixed with self-adhesive resin cement. Material and methods Thirty-six bovine teeth were randomly divided into three groups after endodontic treatment and post space preparation (n = 12): IAC- the fiber posts were cutting immediately after cementation; ACR - the fiber posts were cutting after coronal reconstructi…

CementUniversal testing machineMaterials scienceDrillBond strengthTension (physics)Root canalResearch0206 medical engineering030206 dentistry02 engineering and technologyCementation (geology)020601 biomedical engineeringOperative Dentistry and Endodontics03 medical and health sciences0302 clinical medicinemedicine.anatomical_structuremedicineFiberComposite materialGeneral DentistryUNESCO:CIENCIAS MÉDICASJournal of Clinical and Experimental Dentistry
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Endotoxin inhibition of distension-stimulated gastric acid secretion in rat: mediation by NO in the central nervous system

1995

1. The involvement of nitric oxide in the acute inhibitory effects of low doses of endotoxin, following intracerebroventricular (i.c.v.) or intravenous (i.v.) administration, on gastric acid secretion stimulated by distension or i.v. infusion of pentagastrin has been investigated in the continuously perfused stomach of the anaesthetized rat. 2. The i.c.v. administration of E. coli endotoxin (800 ng kg-1) abolished the acid secretory response induced by gastric distension (20 cm water intragastric pressure) within 30 min of administration. 3. By contrast, submaximal rates of acid secretion induced by i.v. infusion of pentagastrin (8 micrograms kg-1 h-1) were not inhibited by i.c.v. administr…

Central Nervous SystemMalemedicine.medical_specialtyArginineBiologyDistensionArginineNitric OxideNitric oxideGastric Acidchemistry.chemical_compoundInternal medicinemedicineAnimalsSecretionRats WistarPharmacologyStomachGastric distensionRatsEndotoxinsPentagastrinNG-Nitroarginine Methyl Estermedicine.anatomical_structureEndocrinologychemistryGastric acidFemalemedicine.symptomResearch Articlemedicine.drugBritish Journal of Pharmacology
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Nitrergic modulation of gastrointestinal function during early endotoxemia.

2006

After bacterial infection, the host reacts by signalling to the central nervous system where a cascade of physiologic, neuroendocrine and behavioural processes is orchestrated, collectively termed the acute phase response. Endotoxemia following Gram-negative bacterial infection induces a wide array of effects, including fever, loss of appetite and changes in gastrointestinal function that attempt to eliminate the challenge and restore homeostasis. Systemic administration of low doses of endotoxin (5-40 microg/kg) to rats is associated with changes in gastrointestinal motor function, inhibition of gastric acid secretion and increase in the gastric mucosal resistance to damage. These changes …

Central Nervous Systemmedicine.medical_specialtyCentral nervous systemMyenteric PlexusNitric OxideNitric oxideGastric Acidchemistry.chemical_compoundInternal medicineNitrergic NeuronsDrug DiscoverymedicineAnimalsHumansPharmacologyGastrointestinal tractbiologyStomachVagus NerveEndotoxemiaRatsNitric oxide synthaseGastrointestinal Tractmedicine.anatomical_structureEndocrinologychemistryGastric MucosaRegional Blood Flowbiology.proteinGastric acidNitric Oxide SynthaseGastrointestinal functionGastrointestinal MotilityHomeostasisCurrent pharmaceutical design
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Trophic ecology of the swimming crab Polybius henslowii Leach, 1820 in Galician and Cantabrian Seas: Influences of natural variability and the Presti…

2008

9 pages, 9 figures, 2 tables.-- Printed version published Nov 15, 2008.

Centro Oceanográfico de SantanderStomach contentAquatic ScienceOceanographyPredationPrestigeMedio MarinoTrophic levelgeographygeography.geographical_feature_categoryUpwellingbiologyContinental shelfEcologyGeologyPelagic zoneBiomarkerbiology.organism_classificationGaliciaPortunid crabOceanographyProductivity (ecology)SpainBenthic zoneNAOUpwellingGlyceraBiomarkers
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Bond strength evaluation of the veneering-core ceramics bonds.

2009

The purpose of this study was to determine whether the bond of veneering porcelain to a ceramic core in bilayered ceramics was similar to that of the metal ceramic control of well known behaviour. Six groups of nine specimens each were fabricated, whose dimensions were 15 mm long and 8 mm in diameter at the core, and 2 mm long and 8 mm in diameter for the veneer. The groups were GR. 1 (control group): CrNi alloy/d.SIGN (Ivoclar), GR. 2: IPS e.maxPress/IPS e.maxCeram (Ivoclar), GR. 3: IPS e.maxZirCad/ IPS e.maxZirPress (Ivoclar), GR. 4: IPS e.maxZirCad/IPS e.maxCeram (Ivoclar), GR. 5: Lava Frame (3M ESPE)/ Lava Ceram (3M ESPE) and GR. 6: Lava Frame (3M ESPE)/IPS e.maxCeram (Ivoclar). A shear…

CeramicsMaterials scienceShear strength testmedicine.medical_treatmentMateriales dentalesOdontologíaCIENCIA DE LOS MATERIALES E INGENIERIA METALURGICAmedicineCeramicComposite materialGeneral DentistryBond strengthUniversal testing machineBond strengthDental Bonding:CIENCIAS MÉDICAS [UNESCO]CeramicCore (optical fiber)Dental VeneersOtorhinolaryngologyvisual_artUNESCO::CIENCIAS MÉDICASShear testvisual_art.visual_art_mediumZirconiaSurgeryVeneerAdhesiveDirect shear testMedicina oral, patologia oral y cirugia bucal
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Effects of femtosecond laser and other surface treatments on the bond strength of metallic and ceramic orthodontic brackets to zirconia.

2017

Femtosecond laser has been proposed as a method for conditioning zirconia surfaces to boost bond strength. However, metallic or ceramic bracket bonding to femtosecond lasertreated zirconia surfaces has not been tested. This study compared the effects of four conditioning techniques, including femtosecond laser irradiation, on shear bond strength (SBS) of metallic and ceramic brackets to zirconia.Three hundred zirconia plates were divided into five groups: 1) control (C); 2) sandblasting (APA); 3) silica coating and silane (SC); 4) femtosecond laser (FS); 5) sandblasting followed by femtosecond laser (APA+SC). A thermal imaging camera measured temperature changes in the zirconia during irrad…

CeramicsScanning electron microscopeOrthodontic Bracketslcsh:MedicineTissue AdhesionsCoating Materials030207 dermatology & venereal diseases0302 clinical medicineMedicine and Health SciencesSilaneElectron MicroscopyCubic zirconiaCeramicZirconium oxideComposite materiallcsh:ScienceMicroscopyMultidisciplinaryBond strengthBracketTemperatureOptical EquipmentMetalsvisual_artPhysical SciencesFemtosecondvisual_art.visual_art_mediumEngineering and TechnologyScanning Electron MicroscopyShear StrengthResearch ArticleMaterials scienceMaterials by StructureMaterials ScienceOral MedicineEquipmentOrthodonticsResearch and Analysis MethodsENPEP gene03 medical and health sciencesCoatingsAdhesivesShear strengthMaterials by AttributeUniversal testing machineSurface TreatmentsLaserslcsh:R030206 dentistryManufacturing ProcessesMicroscopy Electron Scanninglcsh:QZirconiumPLoS ONE
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System-theoretical analysis of the Clare Bishop Area in the cat

1980

The Clare Bishop Area (CBA) is a retinotopically organized cortical area in the cat brain connected to a great variety of visual areas in a very complex wax (Fig. 1). Experimental analysis is difficult because of the following aspects: 1. As the distance from the retina increases, the signal combinations necessary to analyse the system become more and more specific. 2. Feedback loops cannot be opened, so an unequivocal identification of CBA cell properties is impossible. 3. The nonlinear character seems to have a great influence on signal processing. To circumvent these problems, specific signal combinations leading to a separation of input subsystems have been developed (Hoffmann and v. Se…

Cerebral CortexPolynomialSequenceSignal processingTime FactorsGeneral Computer ScienceComputer scienceEstimation theorySystems TheoryCell CommunicationFunction (mathematics)Models BiologicalSignalNonlinear systemCatsVisual PerceptionFeature (machine learning)AnimalsAlgorithmMathematicsBiotechnologyBiological Cybernetics
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Computational identification of chemical compounds with potential anti-Chagas activity using a classification tree

2021

Chagas disease is endemic to 21 Latin American countries and is a great public health problem in that region. Current chemotherapy remains unsatisfactory; consequently the need to search for new drugs persists. Here we present a new approach to identify novel compounds with potential anti-chagasic action. A large dataset of 584 compounds, obtained from the Drugs for Neglected Diseases initiative, was selected to develop the computational model. Dragon software was used to calculate the molecular descriptors and WEKA software to obtain the classification tree. The best model shows accuracy greater than 93.4% for the training set; the tree was also validated using a 10-fold cross-validation p…

Chagas diseaseComputer scienceTrypanosoma cruziAntiprotozoal AgentsQuantitative Structure-Activity RelationshipBioengineeringLigandsMachine learningcomputer.software_genre01 natural sciencesConstant false alarm rateSoftwareMolecular descriptorDrug DiscoveryChagas Diseaseclassification treeVirtual screeningMolecular Structure010405 organic chemistrybusiness.industryDecision tree learningGeneral Medicinevirtual screening0104 chemical sciences010404 medicinal & biomolecular chemistryIdentification (information)Tree (data structure)Anti-chagasic actionTest setMolecular MedicineArtificial intelligencebusinesscomputerSoftware
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