Search results for "Madi"
showing 10 items of 69 documents
Male mating success during parturial intermoults in the terrestrial isopod Armadillidium vulgare revealed by the use of a microsatellite locus
2007
3 pages; International audience; We investigated the value of microsatellite DNA markers to improve our knowledge of mating strategy with inference to sperm competition in particular, in the woodlouse Armadillidium vulgare. In terrestrial isopods, mature females develop a brood pouch or marsupium before egg laying, the pouch being formed by overlapping oöstegites during a special moult called parturial moult. Under laboratory conditions, we show that Armadillidium vulgare females are able to mate during parturial intermoults, even in the presence of a physical barrier such as that represented by the ventral marsupial plates. Our results reveal that the contribution of a second male mating w…
Modulation of the TGF-β1-induced epithelial to mesenchymal transition (EMT) mediated by P1 and P2 purine receptors in MDCK cells
2017
Epithelial to mesenchymal transition (EMT) occurs during embryogenesis or under pathological conditions such as hypoxia, injury, chronic inflammation, or tissue fibrosis. In renal tubular epithelial cells (MDCK), TGF-β1 induces EMT by reducing or increasing epithelial or mesenchymal marker expression, respectively. In this study, we confirmed that the cAMP analogues, 8-CPT-cAMP or N6-Ph-cAMP, inhibited the TGF-β1-driven overexpression of the mesenchymal markers ZEB-1, Slug, Fibronectin, and α-SMA. Furthermore, we showed that A1, A2A, P2Y1, P2Y11, and P2X7 purine receptor agonists modulated the TGF-β1-induced EMT through the involvement of PKA and/or MAPK/ERK signaling. The stimulation o…
Tetraspanin CD63 controls basolateral sorting of organic cation transporter 2 in renal proximal tubules.
2016
CD63 is a ubiquitously expressed member of the tetraspanin superfamily. Using a mating-based split-ubiquitin-yeast 2-hybrid system, pull-down experiments, total internal reflection fluorescence microscopy, Forster resonance energy transfer, and biotinylation assays, we found that CD63 interacts with human organic cation transporter 2 (hOCT2), which transports endogenous and exogenous substrates, such as neurotransmitters and drugs in several epithelial cells. CD63 overexpression affects cellular localization of hOCT2 expressed in human embryonic kidney (HEK)293 cells. Studies with CD63-knockout mice indicate that in renal proximal tubules, CD63 determines the insertion of the mouse ortholog…
Identification of the Tetraspanin CD9 as an Interaction Partner of Organic Cation Transporters 1 and 2
2019
Organic cation transporters (OCTs) are membrane proteins with relevant physiological (because they accept neurotransmitters as substrate) and pharmacological (because of their interaction with drugs) roles. The human OCTs hOCT1 (SLC22A1/hOCT1) and hOCT2 (SLC22A2/hOCT2) are highly expressed in hepatic (hOCT1) and in renal and neuronal tissue (hOCT2), suggesting a possible role in modulating neurotransmitter activity in the liver, kidney, and brain, and their clearance from the blood. Even though there are several data demonstrating that OCTs are regulated under various patho-physiological conditions, it remains largely unknown which proteins directly interact with OCTs and thereby influence …
Vitamin K antagonists' use and fracture risk: results from a systematic review and meta‐analysis
2015
Background: Although vitamin K antagonists (VKAs) lower serum values of bone deposition markers, the link with osteoporosis and fractures remains controversial. Objectives: To assess whether the use of VKAs is associated with an increased prevalence and/or incidence of osteoporosis, fractures, or lower bone mineral density (BMD) values. Methods: We conducted a systematic PubMed and EMBASE literature search until August 31, 2014, and a meta-analysis of cross-sectional and longitudinal studies investigating fractures and BMD, comparing patients treated with VKAs and healthy controls (HCs) or with patients with medical illness (medical controls, MCs). Standardized mean differences ± 95% and co…
The Added-Value of Remotely-Sensed Soil Moisture Data for Agricultural Drought Detection in Argentina
2021
In countries where the economy relies mostly on agricultural-livestock activities, such as Argentina, droughts cause significant economic losses. Currently, the most-used drought indices by the Argentinian National Meteorological and Hydrological Services are based on field precipitation data, such as the standardized precipitation index (SPI) and the standardized precipitation evapotranspiration index (SPEI). In this article, we explored the performance of the satellite-based soil moisture agricultural drought index (SMADI) for agricultural drought detection in Argentina during 2010-2015, and compared it with the one from the standardized soil moisture anomalies (SSMA), SPI and SPEI (at on…
Ecotourism in Bolivia : an ethnographical study of ecotourism impacts in Madidi National Park
2016
Master thesis development management - University of Agder 2016 The concepts of ecotourism are widely defined but it is often used as a marketing instrument in order to promote tourism businesses related to nature. Ecotourism experience a fast growth in world tourism industry and many developing countries are trying to use ecotourism as a tool to achieve sustainable development. Ecotourism provides many beneficiaries to local environments, economies and socio-cultural lives. However, ecotourism may as well have harmful effects on those involved. Still, ecotourism conserves and protects local areas and its people. Madidi National Park in Bolivia has been estimated to be one of the world’s mo…
Conversion as Negotiation. Converts as Actors of Civil Society
2020
This article focuses on the religious movement of the Ahmadiyya and its civil society organization, Humanity First, in West-Africa and in Europe. Particular attention is paid to the place of converts within these two institutions. Conversions to an Islamic minority and the actions of this minority are studied through the prism of social commitment. I examine the intersections between religious values, the ideas of solidarity in the societies under scrutiny and, the kaleidoscopic range of Muslim charities. The paper investigates conversion as negotiation in regard to gender, social mobility, and power. Conversion is approached here as a matter of social relations and not personal belief. I a…
La calidad periodística mediante el análisis del discurso de los profesionales de la información
2015
La investigación indaga las opiniones de los periodistas sobre la influencia de los cambios en el campo periodístico en las últimas décadas, es decir, qué opinan los periodistas sobre lo que permanece, lo que ha desaparecido y aquello que es nuevo. La base teórica se fundamenta en la teoría del campo y del habitus de Pierre Bourdieu y en el análisis de la estructura comunicativa desde las perspectivas económica, sociológica, históricopolítica y tecnológica. Se han aplicado una serie de métodos complementarios: análisis cualitativo de entrevistas en profundidad y análisis pragmadialéctico de los argumentos de los periodistas entorno al concepto de calidad periodística The research investigat…
Géographie érotique et nomadisme libidinal
2015
International audience