Search results for "Maintena"

An effective approach for the maintenance scheduling in large systems with required reliability level: A case study

2015

This paper deals with the problem of the maintenance scheduling in a multi-component system for which a required reliability level has to be warranted until the next planned stop for maintenance. Particularly, the tackled problem concerns both the determination of the elements set on which to perform preventive maintenance and the optimal number of maintenance crews in order to warranty the required reliability level at the minimum maintenance cost. The problem is formulated as a mathematical programming model that becomes very hard to solve for large practical systems. For such reason, a new effective approach based on a constrained genetic algorithm is herein proposed and tested with refe…

Evaluation of maintenance service procurement contracts

2009

Trabajo y TIC en los mayores de 45 años. Un análisis de la introducción al ciberespacio desde la esfera laboral

2018

The inequality in access to cyberspace due to age at the beginning of the twenty-first century was followed by an economic crisis that intensified many socio-labor dynamics. Through a contextualization with INE data and a qualitative sample, the following work tries to capture the attitudes about ICT related to their previous labor trajectories on those over 45 years of age; and, on the other hand, its introduction to cyberspace from work as a conditioner in the perception of crisis, the maintenance of employment or their way out to retirement.

Data Compensation with Gaussian Processes Regression: Application in Smart Building's Sensor Network

2022

Data play an essential role in the optimal control of smart buildings’ operation, especially in building energy-management for the target of nearly zero buildings. The building monitoring system is in charge of collecting and managing building data. However, device imperfections and failures of the monitoring system are likely to produce low-quality data, such as data loss and inconsistent data, which then seriously affect the control quality of the buildings. This paper proposes a new approach based on Gaussian process regression for data-quality monitoring and sensor network data compensation in smart buildings. The proposed method is proven to effectively detect and compensate for low-qu…

Dialektalny wariant niemczyzny w Gościęcinie na Górnym Śląsku

2015

Die deutsche Sprache in Oberschlesien am Beispiel des Sprachinseldeutschen von Kostenthal/Gościęcin

2017

As one of the most widely spoken languages in the world, German is not any way a uniform from of communication. The present contribution will deal with German in Silesia particularly the German spoken in the Upper Silesian language island (Sprachinsel) of Kostenthal (Gościęcin). Following an introduction to the historical development of this language island. I will present several particularities of this German variety. The idiosyncrasies of the base dialect of Kostenthal that are reflected in the predominant German Umgangssprache spoken locally today will then be shown.

Hallinnan näkökulmia huumeriippuvuuden hoitoon Suomessa vuosina 1965-2005

2011

A randomized controlled trial of high-dose maintenance interferon therapy in chronic hepatitis C

1997

In chronic hepatitis C virus (HCV) infection, the rate of sustained response to interferon is low. We evaluated, in patients responding to a 26-week course of interferon, the effect of high-dose maintenance therapy in preventing relapse. Three hundred and ten patients with chronic HCV infection (38.3% with cirrhosis, 80.6% with HCV type 1) received interferon alfa-2b for 26 weeks (10 MU tiw for 8 weeks, then 5 MU tiw for 18 weeks). One hundred and twenty-four subjects (40%) normalized aminotransferases, and were allocated randomly either to continue on 5 MU tiw for a further 26 weeks (prolonged therapy group: 60 patients) or to stop interferon (brief therapy group: 64 patients). Fifty-two w…

O26 Population pharmacokinetic meta-analysis of individual data to design the first randomized efficacy trial of vancomycin in neonates and young Inf…

2019

BackgroundIn the absence of consensus, the present meta-analysis was performed to determine an optimal dosing regimen of vancomycin for neonates.MethodsA ‘meta-model’ using NONMEM with 4894 concentrations from 1631 neonates was built and Monte Carlo simulations were performed to design an optimal intermittent infusion, aiming at reaching a target AUC0-24 of 400 mg*h/L at steady state in at least 80% of neonates.ResultsA two-compartment model best fitted the data. Current weight, post-menstrual age (PMA) and serum creatinine were the significant covariates for clearance (CL). After model validation, simulations showed that a loading dose (25 mg/kg) and a maintenance dose (15 mg/kg twice dail…

Behavioral and psychological flexibility in eating regulation among overweight adults

2016

Weight-loss programs are often based on self-control techniques and they commonly fail in long-term weight management. Identifying psychological processes that explain eating behaviors can help to develop more effective interventions for long-term weight management. This research examined how behavioral and psychological flexibility are related to eating regulation and weight management in overweight adults. The first goal was to study the effects of flexible vs. rigid restraint of eating on weight-loss maintenance and well-being. The second goal was to examine whether psychological flexibility and mindfulness, independently and together, explain intuitive eating regulation. The third goal …