Search results for "Malalties"
showing 10 items of 396 documents
ALLOPURINOL BLOCKS AORTIC ANEURYSM IN A MOUSE MODEL OF MARFAN SYNDROME VIA REDUCING AORTIC OXIDATIVE STRESS
2022
ABSTRACTBackgroundIncreasing evidence indicates that redox stress participates in MFS aortopathy, though its mechanistic contribution is little known. We reported elevated reactive oxygen species (ROS) formation and NADPH oxidase NOX4 upregulation in MFS patients and mouse aortae. Here we address the contribution of xanthine oxidoreductase (XOR), which catabolizes purines into uric acid and ROS in MFS aortopathy.Methods and ResultsIn aortic samples from MFS patients, XOR protein expression, revealed by immunohistochemistry, increased in both the tunicae intima and media of the dilated zone. In MFS mice (Fbn1C1041G/+), aortic XOR mRNA transcripts and enzymatic activity of the oxidase form (X…
Fibroma osificante maxilar: presentación de un caso y revisión de la literatura
2004
Existe un conjunto de procesos que han sido denominados genéricamente lesiones fibroóseas benignas, entre las que se encuentran la displasia fibrosa, la osteomielitis esclerosante y el fibroma osificante o cementificante. Todos estos procesos tienen un estroma fibroblástico vascular y producen una matriz calcificada que comprende desde el hueso hasta el cemento. El fibroma osificante se caracteriza por presentar un crecimiento y una tumefacción deformante de evolución lenta que generalmente aparece en la mandíbula y puede producir desplazamiento dentario precoz. Desde el punto de vista radiológico aparece generalmente como un área radiotransparente unilocular bien definida y demarcada o com…
Juicio que sobre la methodo controvertida de curar los morbos con el uso del agua y limitacion en los purgantes formaba ... Manuel Gutierrez de los R…
1736
Al lector, prologo que hace Don Juan Vazquez de Cortes ... à cuya diligencia sale à luz esta obra Sign.: [calderó]-5[calderó]4, 6[calderó]1, A-U4, X1 Port. orlada
Inhibición de la proproteína convertasa subtilisina/kexina tipo 9 (PCSK9) en el tratamiento de la hipercolesterolemia.
2016
Se diapome de un nuevo grupo de fármacoshipocolesterolemiantes potentes y bien tolerados, para completar las opciones terapéuticas en sujetos de alto o muy alto riesgo cardiovascular, especialmente con hipercolesterolemia genética, que con el tratamiento habitual, estatinas y asociaciones con ezetimiba o resinas, no consigan llegar a los objetivos propuestos o en aquellos con intolerancia a estatinas y necesidad de disminuir los concentraciones de cLDL por su alto riesgo cardiovascular
Documento de consenso de la Sociedad Española de Arteriosclerosis sobre las indicaciones de los inhibidores de la PCSK9 [Consensus document of the Sp…
2016
La SEA ha consensuado unas indicaciones médicas para el uso de los inhibidores de la PCSK9 (tabla 1), atendiendo a la relación coste/beneficio, y teniendo en cuenta que aún no se dispone de datos sobre la protección de episodios cardiovasculares.
Non-valvular Atrial Fibrillation in CKD: Role of Vitamin K Antagonists and Direct Oral Anticoagulants. A Narrative Review
2021
Atrial fibrillation (AF) is the most common arrhythmia in chronic kidney disease (CKD), with a close bidirectional relationship between the two entities. The presence of CKD in AF increases the risk of thromboembolic events, mortality and bleeding. Vitamin K antagonists (VKA) have been the mainstay of treatment for the prevention of thromboembolic events in AF until recently, with confirmed benefits in AF patients with stage 3 CKD. However, the risk-benefit profile of VKA in patients with AF and stages 4–5 CKD is controversial due to the lack of evidence from randomized controlled trials. Treatment with VKA in CKD patients has been associated with conditions such as poorer anticoagulation q…
Urinary Tartaric Acid, a Biomarker of Wine Intake, Correlates with Lower Total and LDL Cholesterol.
2021
Postmenopausal women are at higher risk of developing cardiovascular diseases due to changes in lipid profile and body fat, among others. The aim of this study was to evaluate the association of urinary tartaric acid, a biomarker of wine consumption, with anthropometric (weight, waist circumference, body mass index (BMI), and waist-to-height ratio), blood pressure, and biochemical variables (blood glucose and lipid profile) that may be affected during the menopausal transition. This sub-study of the PREDIMED (Prevención con Dieta Mediterránea) trial included a sample of 230 women aged 60–80 years with high cardiovascular risk at baseline. Urine samples were diluted and filtered, and tartari…
A systematic review of the effectiveness of dry needling in subacromial syndrome
2022
Our aim was to evaluate the effectiveness of dry needling (DN) combined with conventional physiotherapy in the recovery of patients with subacromial syndrome (SAS). A search was made of the main open access health science databases. The publication date was not limited for systematic reviews but was for randomized clinical trials (RCTs), which were limited to the last five years (from 2016) in English or in Spanish. Ninety-four studies were selected. In order to assess the quality of the studies, the JADAD scale or Oxford quality scoring system was used. A total of 402 patients were analyzed in all the studies in which the application of conventional physiotherapy was compared to the DN, ei…
Suplementos probióticos en enfermedades del entorno gastrointestinal por alteración de la microbiota tras la antibioterapia
2022
Introducción: La microbiota puede verse alterada debido al uso de antibióticos para el tratamiento de enfermedades del entorno gastrointestinal. La suplementación con probióticos podría emplearse terapéuticamente para regular o evitar esta disbiosis. Objetivo: Analizar la información relevante sobre el uso de probióticos como coadyuvante en el tratamiento con antibióticos en enfermedades del entorno gastrointestinal que pueden alterar su microbiota. Métodos: Revisión bibliográfica en bases de datos científicas de artículos relacionados con el tema y publicados entre enero de 2010 a junio de 2020. Se encontraron 132 artículos, 43 se incluyeron tras cumplir los criterios de selección, relevan…
Persistent SARS-CoV-2 infection with repeated clinical recurrence in a patient with common variable immunodeficiency
2021
This work was co-financed by the European Union through the Operational Programme of the European Regional Development Fund of Valencia Region (Spain) 2014–2020.